- Waltham MA, US Gregory P. Chang - Medford MA, US Ann F. Cheung - Lincoln MA, US Asya Grinberg - Lexington MA, US William Haney - Wayland MA, US Nicolai Wagtmann - Concord MA, US Bradley M. Lunde - Lebanon NH, US Bianka Prinz - Lebanon NH, US
International Classification:
C07K 16/28 A61P 35/00
Abstract:
Multi-specific binding proteins that bind to and kill human cancer cells are described, as well as pharmaceutical compositions and therapeutic methods useful for the treatment of cancer. The cancer can be B-cell maturation antigen (BCMA)-expressing cancer. The multi-specific binding proteins provided herein exhibit high potency and maximum lysis of target cells compared to anti-BCMA monoclonal antibodies.
Proteins Binding Nkg2D, Cd16 And An Antigen Associated With Tumors, Mdscs And/Or Tams
- Waltham MA, US Gregory P. Chang - Medford MA, US Ann F. Cheung - Lincoln MA, US Jean-Marie Cuillerot - Somerville MA, US Jinyan Du - Waltham MA, US Asya Grinberg - Lexington MA, US William Haney - Wayland MA, US Steven O'Neil - Wayland MA, US Nicolai Wagtmann - Concord MA, US Bradley M. Lunde - Lebanon NH, US Bianka Prinz - Lebanon NH, US
International Classification:
C07K 16/28 A61P 35/00
Abstract:
Multi-specific binding proteins that bind the NKG2D receptor, CD 16, and a tumor-associated antigen on tumor cells, or an antigen on myeloid-derived suppressor cells or tumor-associated macrophages are described, as well as pharmaceutical compositions and therapeutic methods useful for the treatment of cancer.
- Waltham MA, US Gregory P. Chang - Medford MA, US William Haney - Wayland MA, US Bianka Prinz - Lebanon NH, US Bradley M. Lunde - Lebanon NH, US
International Classification:
C07K 16/30 C07K 16/28 A61P 35/00
Abstract:
Multi-specific binding proteins that bind GD2, the NKG2D receptor, and CD 16 are described, as well as pharmaceutical compositions and therapeutic methods useful for the treatment of cancer.
Compositions And Methods For Growth Factor Modulation
- Cambridge MA, US Gregory P. Chang - Reading MA, US Nagesh K. Mahanthappa - Cambridge MA, US
International Classification:
C07K 16/22 A61K 38/18
Abstract:
Provided herein are proteins, antibodies, assays and methods useful for modulating growth factor levels and/or activities. In some embodiments, such growth factors are members of the TGF-β superfamily of proteins.
Video Destination
Video
Variance Films Oct 2011 - Sep 2013
Film Distribution
Columbia University Medical Center Oct 2011 - Sep 2013
New Media Coordinator
Film Movement Oct 2008 - Feb 2009
Intern
New York Asian Film Festival 2009 - 2009
Print Traffic
Education:
Haverford College 1999 - 2003
Bachelors, Bachelor of Arts, History
Skills:
Video Production Editing Digital Media Social Media Film Management Television Entertainment Nonprofits Final Cut Pro Ableton Live Adobe Premiere Pro
Phi/Cdc Global Health Fellowship Program
Global Health Surveillance Fellow
Icap at Columbia University Apr 2017 - Aug 2018
Population-Based Hiv Impact Assessment Monitoring and Evaluation Intern
Case Western Reserve University Feb 2015 - May 2016
Center For Global Health and Disease Research Assistant
Cleveland Clinic May 2013 - Aug 2014
Student Researcher
Education:
Columbia University Mailman School of Public Health 2016 - 2018
Master of Public Health, Masters, Epidemiology, Global Health
Case Western Reserve University 2013 - 2016
Bachelors, Bachelor of Arts, Bachelor of Science, Anthropology, Biology
Skills:
Research Data Analysis Matlab Powerpoint Microsoft Word
Wilmot Sanz Inc
Principal
Perkins+Will Jan 2013 - Jun 2013
Principal
Aecom Jan 1998 - Jan 2013
Principal, Managing Director, Global Healthcare
Ellerbe Becket 1998 - 2010
Principal, National Director of Healthcare
Kmd Architects Jan 1994 - Jan 1998
Associate, Medical Planner
Education:
The Johns Hopkins University
The Catholic University of America
Bachelor of Architecture, Bachelors, Bachelor of Science
Skills:
Comprehensive Planning Leed Ap Sustainable Design Healthcare Submittals Design Research Architectural Design Leed Revit Bim Architecture Project Management Construction Drawings Feasibility Studies Project Planning Space Planning Green Building Strategic Planning Contract Negotiation Architectures Contract Management Program Management Value Engineering Sketchup Leed Accredited
Nyc Department of Education
Social Studies Teacher
Prepnow Tutoring Jul 1, 2013 - Aug 2014
Tutor
Success Academy Charter Schools Oct 1, 2012 - Jun 1, 2013
Humanities Associate Teacher
Maya Angelou Academy at Is 59 Oct 1, 2011 - Feb 1, 2012
Student Teacher
Craig Johnson For State Senate Sep 1, 2010 - Nov 1, 2010
Field Manager
Education:
University of Southern California 2011 - 2012
Masters, Master of Arts, Teaching, Education, Social Studies
The Johns Hopkins University 2006 - 2010
Bachelors, Bachelor of Arts, Political Science
Skills:
Writing Civic Education Social Media Public Speaking Social Studies Teaching Current Affairs Grand Strategy Government Grip American History World History Microsoft Office Nonprofits Administration Tutoring Critical Thinking Collaboration Has Errors Great Language Arts Politics Research Classroom Political Campaigns Film Production
Interests:
公民権社会貢献 科学技術 環境自然 経済支援 文化芸術 人権保護
Languages:
English Korean Spanish
Certifications:
License 802067131 New York State Education Department, License 802067131 Social Studies 7-12
Emergency Medical Associates (EMA) since Jan 2011
Physician Assistant, Regional Manager
Emergency Medical Associates (EMA) since Aug 1995
Physician Assistant
Education:
Rutgers University/University of Medicine and Dentistry of NJ 1992 - 1995
Rutgers, The State University of New Jersey-New Brunswick 1988 - 1992