Gregory D. Davis - Mountain View CA Helmut Wurst - Cupertino CA
Assignee:
Clontech Laboratories, Inc. - Palo Alto CA
International Classification:
C12Q 168
US Classification:
435 6, 435 911, 435 912, 536 231, 536 2433
Abstract:
Methods are provided for evaluating the fidelity of a given set of polymerase chain reaction conditions. In the subject methods, a template polydeoxyribonucleotide is amplified under the to be evaluated polymerase chain reaction conditions, where the template polydeoxyribonucleotide includes a pseudo restriction endonuclease restriction site. The resultant amplified product population is then contacted with the corresponding restriction endonuclease and resultant cleavage products, if any, are detected. The fidelity of the polymerase chain reaction conditions is then derived from the detected cleavage products (or absence thereof). Also provided are kits for use in practicing the subject methods. The subject methods are suited for determining the fidelity of a given polymerase under PCR conditions, and are particularly suited for determining the fidelity of a thermostable polymerase under PCR conditions.
Systems, Methods, And Devices For Vertically Integrated Instrumentation And Trace Reconstruction
- Santa Barbara CA, US Steven H. Ginzburg - Mountain View CA, US Nikola Valerjev - Goleta CA, US Gregory Davis - Santa Barbara CA, US Greg Eddington - Santa Barbara CA, US Nathan Field - Santa Barbara CA, US Mallory M. Green - Goleta CA, US Phillip Kelly - Goleta CA, US Michael B. Wolf - Blue Hill ME, US Tom Zavisca - Santa Barbara CA, US
International Classification:
G06F 11/36
Abstract:
In an embodiment, a system is configured to replay and/or reconstruct execution events and system states in real time or substantially in real time starting from the point when execution of a target program has stopped to the point when the user desires to step through the target program's execution in order to debug the software. In an embodiment, a system is configured to efficiently collect trace data that is sufficient to reconstruct the state of a computer system at any point of time from the start of execution to the time execution was stopped. Efficient and effective debugging of the software can be performed using embodiments of the disclosed methods, systems, and devices.
The present invention provides RNA-guided endonucleases, which are engineered for expression in eukaryotic cells or embryos, and methods of using the RNA-guided endonuclease for targeted genome modification in in eukaryotic cells or embryos. Also provided are fusion proteins, wherein each fusion protein comprises a CRISPR/Cas-like protein or fragment thereof and an effector domain. The effector domain can be a cleavage domain, an epigenetic modification domain, a transcriptional activation domain, or a transcriptional repressor domain. Also provided are methods for using the fusion proteins to modify a chromosomal sequence or regulate expression of a chromosomal sequence.
- St. Louis MO, US Gregory Davis - Berkeley CA, US
International Classification:
C12N 15/85 C12N 9/22 C12N 15/90
Abstract:
The present invention provides methods for modifying chromosomal sequences. In particular, methods are provided for using RNA-guided endonucleases or modified RNA-guided endonucleases to modify targeted chromosomal sequences.
The present invention provides RNA-guided endonucleases, which are engineered for expression in eukaryotic cells or embryos, and methods of using the RNA-guided endonuclease for targeted genome modification in in eukaryotic cells or embryos. Also provided are fusion proteins, wherein each fusion protein comprises a CRISPR/Cas-like protein or fragment thereof and an effector domain. The effector domain can be a cleavage domain, an epigenetic modification domain, a transcriptional activation domain, or a transcriptional repressor domain. Also provided are methods for using the fusion proteins to modify a chromosomal sequence or regulate expression of a chromosomal sequence.
Systems, Methods, And Devices For Vertically Integrated Instrumentation And Trace Reconstruction
- Santa Barbara CA, US Steven H. Ginzburg - Mountain View CA, US Nikola Valerjev - Goleta CA, US Gregory Davis - Santa Barbara CA, US Greg Eddington - Santa Barbara CA, US Nathan Field - Santa Barbara CA, US Mallory M. Green - Goleta CA, US Phillip Kelly - Goleta CA, US Michael B. Wolf - Blue Hill ME, US Tom Zavisca - Santa Barbara CA, US
International Classification:
G06F 11/36
Abstract:
In an embodiment, a system is configured to replay and/or reconstruct execution events and system states in real time or substantially in real time starting from the point when execution of a target program has stopped to the point when the user desires to step through the target program's execution in order to debug the software. In an embodiment, a system is configured to efficiently collect trace data that is sufficient to reconstruct the state of a computer system at any point of time from the start of execution to the time execution was stopped. Efficient and effective debugging of the software can be performed using embodiments of the disclosed methods, systems, and devices.
The present invention provides RNA-guided endonucleases, which are engineered for expression in eukaryotic cells or embryos, and methods of using the RNA-guided endonuclease for targeted genome modification in in eukaryotic cells or embryos. Also provided are fusion proteins, wherein each fusion protein comprises a CRISPR/Cas-like protein or fragment thereof and an effector domain. The effector domain can be a cleavage domain, an epigenetic modification domain, a transcriptional activation domain, or a transcriptional repressor domain. Also provided are methods for using the fusion proteins to modify a chromosomal sequence or regulate expression of a chromosomal sequence.
Engineered Cas9 Systems For Eukaryotic Genome Modification
Engineered Cas9 systems that utilize alternate protospacer adjacent motifs for target DNA binding, nucleic acids encoding the engineered Cas9 systems, and methods of using the engineered Cas9 systems for modifying target chromosomal sequences in eukaryotic cells.
Gregory L Davis MD 1560 Humboldt Rd STE 3, Chico, CA 95928 5303329703 (phone), 5308948505 (fax)
Education:
Medical School Loma Linda University School of Medicine Graduated: 1982
Procedures:
Colposcopy Cystoscopy D & C Dilation and Curettage Hysterectomy Myomectomy Skin Tags Removal Tubal Surgery Urinary Flow Tests Vaccine Administration
Conditions:
Abnormal Vaginal Bleeding Breast Disorders Candidiasis of Vulva and Vagina Cervical Cancer Complicating Pregnancy or Childbirth
Languages:
English
Description:
Dr. Davis graduated from the Loma Linda University School of Medicine in 1982. He works in Chico, CA and specializes in Gynecology. Dr. Davis is affiliated with Enloe Medical Center and Feather River Hospital.
Dr. Davis graduated from the Ohio University College of Osteopathic Medicine in 1998. He works in Cleveland, OH and 1 other location and specializes in Internal Medicine. Dr. Davis is affiliated with Euclid Hospital, Hillcrest Hospital, St Vincent Charity Medical Center, University Hospitals Parma Medical Center and University Hospitals Richmond Medical Center.
University Of Kentucky Healthcare Pathology 800 Rose St, Lexington, KY 40536 8593235000 (phone), 8593232094 (fax)
Education:
Medical School University of Tennessee College of Medicine at Memphis Graduated: 1985
Languages:
English
Description:
Dr. Davis graduated from the University of Tennessee College of Medicine at Memphis in 1985. He works in Lexington, KY and specializes in Anatomic Pathology & Clinical Pathology. Dr. Davis is affiliated with UK Health Care Good Samaritan Hospital and University Of Kentucky Albert B Chandler Medical Center.
Western Arkansas Anesth AssocWestern Arkansas Anesthesiology 7301 Rogers Ave, Fort Smith, AR 72903 4794521581 (phone)
Education:
Medical School University of California, San Diego School of Medicine Graduated: 1986
Languages:
English Spanish
Description:
Dr. Davis graduated from the University of California, San Diego School of Medicine in 1986. He works in Fort Smith, AR and specializes in Anesthesiology. Dr. Davis is affiliated with Mercy Hospital Fort Smith.
Medical School Emory University School of Medicine Graduated: 1998
Languages:
English Spanish
Description:
Dr. Davis graduated from the Emory University School of Medicine in 1998. He works in Greenville, NC and specializes in Anesthesiology. Dr. Davis is affiliated with Vidant Beaufort Hospital and Vidant Medical Center.
2007 to 2000 Senior Desktop Support EngineerProactive Business Solutions Oakland, CA 2006 to 2007 Project Installation TechnicianQwest Communications Arlington, VA 1998 to 2006 Site ManagerCompucom McLean, VA 1996 to 1998 Escalation Engineer
2012 to 2000 Chemical Biological Radiological Nuclear SpecialistEnvision: National Youth Leadership Forum San Francisco, CA Jun 2013 to Aug 2013 Forum LeaderWest TN Gospel Power Jackson, TN 2009 to 2010 Executive Sales AssistantLane College
2008 to 2010 Dean/Radio PersonalityUpward Bound
2006 to 2009 Evening Program DirectorWalgreen's Jackson, TN 2006 to 2007 Store Cashier/Photo Specialist
Education:
Lane College 2009 Bachelor of Science in Sociology
May 2011 to Present Americas Field Marketing ManagerSilver Creek Valley San Jose, CA 2008 to 2010 Golf Services Manager/PGA ApprenticeRocklin Today Rocklin, CA 2003 to 2006 Owner/Director of MarketingCollaborative Media Inc San Francisco, CA 2000 to 2003 General ManagerIcon Medialab Inc. AB Stockholm 1998 to 2000 Vice President, Global Business DevelopmentCompaq Computer Corp Houston, TX 1997 to 1998 National Reseller ManagerSilicon Graphics Inc Mountain View, CA 1995 to 1997 Manager Indirect ChannelsStereoGraphics Corp Sausalito, CA 1992 to 1995 Product Marketing ManagerAutodesk Inc San Rafael, CA 1989 to 1992 Dealer Sales
Education:
Harvard 1995 to 1996 Certificate in Business ReviewDale Carnegie 1990 to 1992 Sales CourseBluffton College 1987 to 1988 Business Finance
Means Without End: A Critical Survey of the Ideological Genealogy of the Culture of Technology Without Limits, from Apollonian Techne to Postmadern Technoculture
Three Embarcadero Center, San Francisco, CA 94111 4153156327 (Office), 4153156315 (Fax) Ropes & Gray LLP One Embarcadero Center Suite 2200, San Francisco, CA 94111 4153156327 (Office), 4153154802 (Fax)
Licenses:
California - Active 2003 Massachusetts - Active 1996
Education:
Harvard University Law School Degree - JD - Juris Doctor - Law Graduated - 1996 University of California - Davis Degree - BA - Bachelor of Arts Graduated - 1993
The private autopsy was conducted by the chief forensic pathologist for the Washington D.C. area Dr. Roger Mitchell, Crump said. Mitchell met with Chief Medical Examiner of Jefferson County Dr. Gregory Davis and reviewed all death investigation photographs, along with examining the body.
Date: Dec 03, 2018
Category: Headlines
Source: Google
Fats Domino's hits, killer piano fuel New Orleans Jazz Fest tribute show
Deacon John Moore kicked off the dance party, organized by Gregory Davis, co-founder of the Dirty Dozen Brass Band, at the Acura Stage just before 2 p.m., with "Going to the River," a remarkably exuberant take on the song about heartbreak and suicide. Impeccably dressed in a linen jacket with dark b
Date: Apr 28, 2018
Category: Entertainment
Source: Google
Tribeca Film Festival Announces Full Slate, Nearly Half Directed by Women
Jonathan, directed by Bill Oliver, written by Peter Nickowitz, Bill Oliver, Gregory Davis. Produced by Randy Manis, Ricky Tollman. (USA) World Premiere. Jonathan is a young man with a strange condition that only his brother understands. But when he begins to yearn for a different life, their uni
Date: Mar 07, 2018
Category: Entertainment
Source: Google
2 men plead guilty in 2011 racial beatings in Mississippi
shot ball bearings from a slingshot and tried to run someone down. Blalack said that at least one of the trips was in Brandon, and that while most of the intended victims were black, at least one was white. U.S. Attorney Gregory Davis said authorities have never found anyone else who was victimized.
A federal magistrate in Jackson denied bond Thursday to 54-year-old Jesse Mae Pollard, of Northport, Ala., near Tuscaloosa, U.S. Attorney Gregory Davis said in a news release. She has been charged with kidnapping and is to be held until a federal grand jury hears her case, he said in the statement.
Date: May 02, 2013
Category: U.S.
Source: Google
Vanguard Finally Says It Will Launch International-Bond Funds
Human ElementsThe funds will have accomplished index-trackers at their helms. The head of Vanguard's bond index group, Gregory Davis, will run the two funds with Yan Pu. Davis has worked in the family's fixed-income indexing group for more than a decade and is a listed manager on nearly 20 funds, i
Date: Nov 01, 2011
Category: Business
Source: Google
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Gregory Davis
Work:
Comcast - Sr. Engineer The Gov - Computer Engineer (2003-2011)
Education:
University of Maryland Baltimore County - Computer Engineering, Stevens Institute of Technology - Computer Engineering
About:
I'm Greg. If you know where Tastee's or Magic Rice or Bootleggers or Sweet Jenny's are, you probably know me.
Gregory Davis
Education:
Hudson High School
Gregory Davis
Lived:
Crocket california San francisco ca
Gregory Davis
Work:
Nothing
Gregory Davis
Work:
MediaMath, Inc. - Sr. Systems Architect (2010)
Gregory Davis
Education:
University of Maryland University College - Psychology