Gregory Alan Watson

US Patent:

6582387, Jun 24, 2003

Filed:

Mar 20, 2001

Appl. No.:

09/813068

Inventors:

Daw J. Derek - Costa Mesa CA
William R. Patterson - Irvine CA
Stephen E. Myrick - Tustin CA
Jeffrey L. Creech - Marina Del Rey CA
Vincent Divino, Jr. - Mission Viejo CA
Gregory P. Watson - Laguna Niguel CA
Paul J. Zalesky - Huntington Beach CA

Assignee:

TherOx, Inc. - Irvine CA

International Classification:

A61M 3700

US Classification:

604 614, 604 616, 604 401, 12820014, 422 45

Abstract:

A system utilizes an oxygenation device to generate a gas-enriched physiologic fluid and to combine it with a bodily fluid to create a gas-enriched bodily fluid. The oxygenation device may take the form of a disposable cartridge, which is placed within an enclosure. An electronic controller manages various aspects of the system, such as the production of gas-enriched fluids, flow rates, bubble detection, and automatic operation and shut down.

US Patent:

6613280, Sep 2, 2003

Filed:

Mar 20, 2001

Appl. No.:

09/813062

Inventors:

Stephen E. Myrick - Tustin CA
Gregory P. Watson - Laguna Niguel CA
William R. Patterson - Irvine CA
Paul J. Zalesky - Huntington Beach CA

Assignee:

Therox, Inc. - Irvine CA

International Classification:

A61M 114

US Classification:

422 45, 422 44, 12820014, 604 401, 604 614

Abstract:

A device generates a gas-enriched physiologic fluid and combines it with a bodily fluid to create a gas-enriched bodily fluid. The device may take the form of a disposable cartridge. The cartridge may include a fluid supply chamber for delivering physiologic fluid under pressure to an atomizer. The atomizer delivers fluid droplets into a gas-pressurized atomization chamber to enrich the physiologic fluid with the gas. The gas-enriched physiologic fluid is delivered to a mixing chamber in the cartridge where the gas-enriched physiologic fluid is mixed with a bodily fluid, such as blood, to create a gas-enriched bodily fluid.

US Patent:

D497989, Nov 2, 2004

Filed:

Mar 1, 2002

Appl. No.:

29/156499

Inventors:

Stephen E. Myrick - Tustin CA
Mark S. Buhr - Huntington Beach CA
William R. Patterson - Irvine CA
Gregory P. Watson - Laguna Niguel CA

Assignee:

TherOx, Inc. - Irvine CA

International Classification:

2902

US Classification:

D241106, D24164

US Patent:

6974435, Dec 13, 2005

Filed:

Oct 24, 2002

Appl. No.:

10/279507

Inventors:

Derek J. Daw - Costa Mesa CA, US
William R. Patterson - Irvine CA, US
Stephen E. Myrick - Tustin CA, US
Jeffrey L. Creech - Marina Del Rey CA, US
Vincent Divino, Jr. - Mission Viejo CA, US
Gregory P. Watson - Laguna Niguel CA, US
Paul J. Zalesky - Huntington Beach CA, US

Assignee:

TherOx, Inc - Irvine CA

International Classification:

A61M037/00

US Classification:

604 614

Abstract:

A system utilizes an oxygenation device to generate a gas-enriched physiologic fluid and to combine it with a bodily fluid to create a gas-enriched bodily fluid. The oxygenation device may take the form of a disposable cartridge, which is placed within an enclosure. An electronic controller manages various aspects of the system, such as the production of gas-enriched fluids, flow rates, bubble detection, and automatic operation and shut down.

US Patent:

7198179, Apr 3, 2007

Filed:

Feb 25, 2003

Appl. No.:

10/374220

Inventors:

John S. Gilkerson - Cypress CA, US
Jeffrey L. Creech - Marina Del Rey CA, US
Li-Chien Hsu - Mission Viejo CA, US
Gregory P. Watson - Laguna Niguel CA, US

Assignee:

TherOx, Inc. - Irvine CA

International Classification:

B65D 83/00

US Classification:

2224021, 222105

Abstract:

A packaged gas-solubilized product is described. The gas-solubilized product contains a first gas with a first pressure. The product is placed into a flexible inner container made of a gas-impermeable material. The inner container is hermetically disposed inside an outer container. A space formed between the inner and the outer containers is charged with a second gas with an initial charging pressure. The initial charging pressure is higher than the pressure of the first gas contained in the product. Additionally, a product dispenser in a fluid connection with the product contained in the internal container is included. The present invention also provides a method of packaging a gas-solubilized product to prevent a change in the concentration of the gas dissolved in the product during its storage and dispensing.

US Patent:

7820102, Oct 26, 2010

Filed:

Mar 28, 2003

Appl. No.:

10/402463

Inventors:

Stephen E. Myrick - Tustin CA, US
Gregory P. Watson - Laguna Niguel CA, US
William R. Patterson - Irvine CA, US
Paul J. Zalesky - Huntington Beach CA, US

Assignee:

TherOx, Inc. - Irvine CA

International Classification:

A61M 1/00
A61M 37/00

US Classification:

422 44, 422 45, 604 401, 604 614, 604 615

Abstract:

A device generates a gas-enriched physiologic fluid and combines it with a bodily fluid to create a gas-enriched bodily fluid. The device may take the form of a disposable cartridge. The cartridge may include a fluid supply chamber for delivering physiologic fluid under pressure to an atomizer. The atomizer delivers fluid droplets into a gas-pressurized atomization chamber to enrich the physiologic fluid with the gas. The gas-enriched physiologic fluid is delivered to a mixing chamber in the cartridge where the gas-enriched physiologic fluid is mixed with a bodily fluid, such as blood, to create a gas-enriched bodily fluid.

US Patent:

8192384, Jun 5, 2012

Filed:

Dec 4, 2008

Appl. No.:

12/328664

Inventors:

Stephen E. Myrick - Tustin CA, US
Gregory P. Watson - Laguna Niguel CA, US
Achilles V. Young - Aliso Viejo CA, US

Assignee:

TherOx, Inc. - Irvine CA

International Classification:

A61M 37/00

US Classification:

604 401, 422 45

Abstract:

This invention discloses a modular system having a base module, a mid-section control module, and a display module for preparing and administering a gas-enriched bodily fluid. An apparatus adapted for connecting with a gas tank is included in the system for gas tank hook-up. Gas-enrichment is achieved by a gas-enriching device which can be in the form of a disposable cartridge. During operation, the gas-enrichment device is placed in an enclosure within the control module. An electronic controller manages the various aspects of the system such as the production of gas-enriched fluid, flow rates, bubble detection, and automatic operation and shut down. The system has a power supply for providing electrical power to the system, and a switching mechanism coupled to the power supply and gas tank for synchronized switching of the power supply and the gas tank between an ON state and an OFF state.

US Patent:

8246564, Aug 21, 2012

Filed:

Dec 4, 2008

Appl. No.:

12/328635

Inventors:

Stephen E. Myrick - Tustin CA, US
Gregory P. Watson - Laguna Niguel CA, US
John S. Gilkerson - Cypress CA, US
John M. Aoki - Cerritos CA, US

Assignee:

TherOx, Inc. - Irvine CA

International Classification:

A61M 37/00
A61M 1/00

US Classification:

604 401, 604 614, 422 44

Abstract:

This invention discloses a modular system having a base module, a mid-section control module, and a display module for preparing and administering a gas-enriched bodily fluid. Gas-enrichment is achieved by a gas-enriching device which can be in the form of a disposable cartridge. During operation, the gas-enrichment device is placed in an enclosure within the control module to form a fluid pathway for extracorporeal circulation of the bodily fluid. An electronic controller manages the various aspects of the system and executes an automated method for priming the extracorporeal circuit.