Guiren Wang

US Patent:

7428848, Sep 30, 2008

Filed:

Aug 9, 2005

Appl. No.:

11/199754

Inventors:

Kapil Pant - Huntsville AL, US
Guiren Wang - Huntsville AL, US
Jianjun Feng - Huntsville AL, US
Shankar Sundaram - Madison AL, US

Assignee:

CFD Research Corporation - Huntsville AL

International Classification:

G01N 1/24

US Classification:

7386321, 73 2802, 73 2804, 7386433, 7386434, 250288, 435 30, 4353091

Abstract:

The present invention is an electrostatic collector for low cost, high throughput, high efficiency sampling and concentration of bioaerosols. The device is small enough to be portable and can be contained within or placed on the wall of a typical office or hospital building. The collector comprises one or more collector modules, each having an ionizing electrode, a conical outer electrode, a wet collection electrode, and a liquid collection system. Airflow through a collector module may be partially blocked to enhance the collection of smaller particles and the collection electrode may comprise multiple, programmable electrodes to focus particle deposition onto a smaller area. Particles are collected into a small volume of liquid to facilitate subsequent analysis by an attached analyzer or at a remote site.

US Patent:

7842006, Nov 30, 2010

Filed:

Nov 17, 2006

Appl. No.:

11/561303

Inventors:

Guiren Wang - Huntsville AL, US
Shivshankar Sundaram - Madison AL, US
Kapil Pant - Huntsville AL, US
Jianjun Feng - Cincinnati OH, US
Peter Storm - Madison AL, US

Assignee:

CFD Research Corporation - Huntsville AL

International Classification:

A61B 17/22

US Classification:

604 22

Abstract:

The present invention is an ultrasonic thrombectomy catheter that produces physical forces (shear rates) strong enough to emulsify obstructions such as thrombi and emboli without causing damage to arterial walls. This is accomplished by properly arranging piezoelectric transducers within a catheter and a tubular catheter head separated by a gap to generate acoustic streaming that simultaneously emulsifies the obstruction and sweeps resulting debris into a catheter lumen for removal. The open gap may be formed by supporting struts that connect the catheter to the catheter head. The design of the catheter tip allows the fabrication of catheters capable of removing partial or complete blockages from arteries and other vessels having diameters as small as 2 mm.

US Patent:

7998328, Aug 16, 2011

Filed:

Jun 27, 2005

Appl. No.:

11/167428

Inventors:

Jianjun Feng - Huntsville AL, US
Guiren Wang - Huntsville AL, US
Sivaramakrishnan Krishnamoorthy - Madison AL, US
Kapil Pant - Huntsville AL, US
Shivshankar Sundaram - Madison AL, US

Assignee:

CFD Research Corporation - Huntsville AL

International Classification:

B03C 5/02

US Classification:

204643, 204450, 204600, 204547

Abstract:

Methods and apparatus for the micro-scale, dielectrophoretic separation of particles are provided. Fluid suspensions of particles are sorted and separated by dielectrophoretic separation chambers that have at least two consecutive, electrically coupled planar electrodes separated by a gap in a fluid flow channel. The gap distance as well as applied potential can be used to control the dielectrophoretic forces generated. Using consecutive, electrically coupled electrodes rather than electrically coupled opposing electrodes facilitates higher flow volumes and rates. The methods and apparatus can be used, for example, to sort living, damaged, diseased, and/or dead cells and functionalized or ligand-bound polymer beads for subsequent identification and/or analysis.

US Patent:

20070110625, May 17, 2007

Filed:

Sep 6, 2006

Appl. No.:

11/516269

Inventors:

Sivaramakrishnan Krishnamoorthy - Madison AL, US
Guiren Wang - Huntsville AL, US
Jianjun Feng - Cincinnati OH, US
Yi Wang - Madison AL, US

International Classification:

B01L 3/00

US Classification:

422099000

Abstract:

A micropump that pumps liquid using electrothermally-induced flow is described, along with a corresponding self-regulating pump and infusion pump. The micropump has applications in microfluidic systems such as biochips. The self-regulating infusion pump is useful for the administration of large and small volumes of liquids such as drugs to patients and can be designed for a wide range of flow rates by combining multiple micropumps in one infusion pump system.

US Patent:

20070206179, Sep 6, 2007

Filed:

Mar 3, 2006

Appl. No.:

11/368063

Inventors:

Guiren Wang - Huntsville AL, US
Hong Jiang - Huntsville AL, US

International Classification:

G01P 3/36
G01F 25/00

US Classification:

356028000, 073001240

Abstract:

Methods and apparatus for fluid flow velocity and flow rate measurement are provided. Fluid velocity is measured in optical method based on fluorescence photobleaching of a fluorescent dye. The invented method and apparatus requires a calibration relation between flow velocity and fluorescence signal and is easy to use. The invented method and apparatus can measure bulk flow velocity and flow rate inline, two and three components of flow velocity vector. It can also measure flow velocity in near wall region using evanescent wave. Since the invented method and apparatus uses molecular dye and calibration relation between flow velocity and fluorescence signal, it has ultra high spatial and temporal resolution. The invented method can be used not only to apparatuses and devices in conventional size, but also to that in MEMS and NEMS.

US Patent:

20160235912, Aug 18, 2016

Filed:

Dec 16, 2015

Appl. No.:

14/971715

Inventors:

- Huntsville AL, US
Guiren Wang - Huntsville AL, US
Jianjun Feng - Cincinnati OH, US
Yi Wang - Madison AL, US

International Classification:

A61M 5/142
A61M 5/168

Abstract:

A micropump that pumps liquid using electrothermally-induced flow is described, along with a corresponding self-regulating pump and infusion pump. The micropump has applications in microfluidic systems, such as biochips. The self-regulating infusion pump is useful for administration of large and small volumes of liquids such as drugs to patients and can be designed for a wide range of flow rates by combining multiple micropumps in one infusion pump system. The micropump uses electrode sequences on opposing surfaces of a flow chamber that are staggered with respect to each other. The opposing surfaces include staggered electrodes that have the same phase and same electrode sequence. As such electrodes with the same phase are staggered and not eclipsed.