Boston Chinatown Neighborhood Center
Preschool Teacher
Education:
Cambridge College
Skills:
Curriculum Development Program Development Early Childhood Education Child Development Childcare Nonprofits Curriculum Design Volunteer Management Tutoring
Harriet L. Robinson - Southboro MA, US Ellen F. Fynan - Sterling MA, US Robert G. Webster - Memphis TN, US Shan Lu - Northboro MA, US
Assignee:
University of Massachusetts Medical Center - Worcester MA St. Jude Children's Research Hospital - Memphis TN
International Classification:
C12N 1563 C12N 1500
US Classification:
4353201, 435 691, 435325, 435455
Abstract:
This invention relates to a method of immunizing a vertebrate, comprising introducing into the vertebrate a DNA transcription unit which comprises DNA encoding a desired antigen or antigens. The uptake of the DNA transcription unit by a host vertebrate results in the expression of the desired antigen or antigens, thereby eliciting humoral or cell-mediated immune responses or both humoral and cell-mediated responses. The elicited humoral and cell-mediated immune response can provide protection against infection by pathogenic agents, provide an anti-tumor response, or provide contraception. The host can be any vertebrate, avian or mammal, including humans.
Genetic Induction Of Anti-Viral Immune Response And Genetic Vaccine For Viruses
Harriet Robinson - Southborough MA, US Joel Haynes - Middleton WI, US
International Classification:
A61K 48/00 A61K 39/145
US Classification:
514044000, 424209100
Abstract:
An approach to genetic vaccine methodology is described. A genetic construction encoding antigenic determinants of a virus is transfected into cells of the vaccinated individuals using a particle acceleration protocol so as to express the viral antigens in healthy cells to produce an immune response to those antigens.
Immunization By Inoculation Of Dna Transcription Unit
Harriet L. Robinson - Southboro MA Ellen F. Fynan - Sterling MA Robert G. Webster - Memphis TN
Assignee:
University of Massachusetts Medical Center - Worcester MA St. Jude Children's Research Hospital - Memphis TN
International Classification:
A61K 39145 A61K 3900 C07H 2104 C12N 1511
US Classification:
4242101
Abstract:
This invention relates to a method of immunizing a vertebrate, comprising introducing into the vertebrate a DNA transcription unit which comprises DNA encoding a desired antigen or antigens. The uptake of the DNA transcription unit by a host vertebrate results in the expression of the desired antigen or antigens, thereby eliciting humoral or cell-mediated immune responses or both humoral and cell-mediated responses. The elicited humoral and cell-mediated immune responses can provide protection against infection by pathogenic agents, provide an anti-tumor responses, or provide contraception. The host can be any vertebrate, avian or mammal, including humans.
Researcher Dr. Harriet Robinson says the technology works by using only a tiny, harmless section of an Ebola virus cell to produce particles that trigger an immune response. "What you do is just use the parts of the virus that you need to produce virus-like particles and those are particularly good