Heather Douza Cox

US Patent:

20170321289, Nov 9, 2017

Filed:

Jul 13, 2017

Appl. No.:

15/649181

Inventors:

- Los Gatos CA, US
Nikol de Forest - Scotts Valley CA, US
Heather Cox - Los Gatos CA, US
Soni Shukla - Santa Clara CA, US

International Classification:

C12Q 1/68
C12N 15/70
C12N 1/20
C12Q 1/18
C12Q 1/66
C12Q 1/14
C12N 7/00
C12N 15/74

Abstract:

Methods and systems are provided for packaging reporter nucleic acid molecules into non-replicative transduction particles for use as reporter molecules. The non-replicative transduction particles can be constructed from viruses and use viral transduction and replication systems. The reporter nucleic acid molecules include a reporter gene, such as a reporter molecule or selectable marker, for detecting target genes or cells. Methods and systems are provided for detection of cells and target nucleic acid molecules using the non-replicative transduction particles as reporter molecules.

US Patent:

20160281179, Sep 29, 2016

Filed:

Jun 13, 2016

Appl. No.:

15/180790

Inventors:

- Los Gatos CA, US
Nikol de Forest - Scotts Valley CA, US
Heather Cox - Los Gatos CA, US
Soni Shukla - Santa Clara CA, US

International Classification:

C12Q 1/68
C12Q 1/14
C12Q 1/18
C12N 7/00

Abstract:

Methods and systems are provided for packaging reporter nucleic acid molecules into non-replicative transduction particles for use as reporter molecules. The non-replicative transduction particles can be constructed from viruses and use viral transduction and replication systems. The reporter nucleic acid molecules include a reporter gene, such as a reporter molecule or selectable marker, for detecting target genes or cells. Methods and systems are provided for detection of cells and target nucleic acid molecules using the non-replicative transduction particles as reporter molecules.

US Patent:

20160281180, Sep 29, 2016

Filed:

Jun 15, 2016

Appl. No.:

15/183303

Inventors:

- Los Gatos CA, US
Nikol de Forest - Scotts Valley CA, US
Heather Cox - Los Gatos CA, US
Soni Shukla - Santa Clara CA, US

International Classification:

C12Q 1/68
C12Q 1/18
C12Q 1/14
C12N 7/00
C12N 15/70

Abstract:

Methods and systems are provided for packaging reporter nucleic acid molecules into non-replicative transduction particles for use as reporter molecules. The non-replicative transduction particles can be constructed from viruses and use viral transduction and replication systems. The reporter nucleic acid molecules include a reporter gene, such as a reporter molecule or selectable marker, for detecting target genes or cells. Methods and systems are provided for detection of cells and target nucleic acid molecules using the non-replicative transduction particles as reporter molecules.

US Patent:

20150104787, Apr 16, 2015

Filed:

Nov 21, 2014

Appl. No.:

14/550335

Inventors:

- Los Gatos CA, US
Nikol DeForest - Scotts Valley CA, US
Heather Cox - Los Gatos CA, US
Soni Shukla - Santa Clara CA, US

International Classification:

C12Q 1/66
C12N 15/74
C12N 7/00
C12N 1/20

US Classification:

435 61, 4353201, 4352521, 435 36, 435 8, 435 71

Abstract:

Methods and systems are provided for packaging reporter nucleic acid molecules into non-replicative transduction particles for use as reporter molecules. The non-replicative transduction particles can be constructed from viruses and use viral transduction and replication systems. The reporter nucleic acid molecules include a reporter gene, such as a reporter molecule or selectable marker, for detecting target genes or cells. Methods and systems are provided for detection of cells and target nucleic acid molecules using the non-replicative transduction particles as reporter molecules.