Heather M Jones

US Patent:

20200069197, Mar 5, 2020

Filed:

Feb 27, 2018

Appl. No.:

16/489334

Inventors:

- Melbourne, Victoria, AU
- Los Angeles CA, US
Heather JONES - Malibu CA, US
Victor TAPSON - Studio City CA, US

International Classification:

A61B 5/02
A61B 5/0205
A61B 5/107
A61B 5/00
G16H 30/40
G16H 50/20
G16H 20/10

Abstract:

The invention relates to a method of scanning for vascular ill health using a data set from an in vivo scan, the method including the steps of: (1) extracting blood vessel location data and blood vessel size data from the scan data set; (2) selecting a region in the extracted vessel location data; and (3) comparing the size data in the selected region to size data in a corresponding region of a normative data set to determine vascular health.

US Patent:

20200002727, Jan 2, 2020

Filed:

Feb 17, 2018

Appl. No.:

16/486363

Inventors:

- Visp, CH
- New York NY, US
Mark MOFFAT - New York NY, US
Gerald Fries CASPERSON - New York NY, US
Heather Laurence JONES - New York NY, US
Lin ZHANG - New York NY, US

International Classification:

C12N 15/90
C12N 9/12
C12N 15/86
C07K 16/28
C07K 16/30
C07K 14/55
C07K 16/24

Abstract:

The present disclosure relates to a site-specific integration (SSI) mammalian cell that comprises at least two distinct recombination target sites (RTS) wherein two RTS are chromosomally-integrated within the NL1 locus or the NL2 locus. The disclosure also relates to a SSI mammalian cell comprising at least four distinct RTS wherein two RTS are chromosomally-integrated within the NL1 or the NL2 locus and two RTS are chromosomally-integrated within a separate locus. The disclosure also relates to methods for using the SSI mammalian cell to produce recombinant protein expression cell lines that can express difficult to express proteins.