- Irving TX, US Tassilo Hornung - Phoenix AZ, US Heather O'Neill - Mesa AZ, US Mark Miglarese - Phoenix AZ, US David Spetzler - Paradise Valley AZ, US
International Classification:
C12N 15/115 C12N 15/10 C12Q 1/6883 C12Q 1/6886
Abstract:
Methods and compositions are provided to identify oligonucleotides that bind targets of interest. The targets include tissues, cells, circulating biomarkers such as microvesicles, including those derived from various diseases. The oligonucleotides can be used in diagnostic and therapeutic applications.
- Irving TX, US Heather O'Neill - Mesa AZ, US Mark Miglarese - Phoenix AZ, US David Spetzler - Paradise Valley AZ, US
International Classification:
C12N 15/115 C12Q 1/70 A61K 31/7088
Abstract:
Methods and compositions are provided for oligonucleotides and libraries of oligonucleotides that bind targets of interest. The targets include cellular biomarkers of viral infection. The viral infection may be that of human immunodeficiency virus-1.
- Irving TX, US Tassilo HORNUNG - Phoenix AZ, US Heather O'NEILL - Mesa AZ, US Mark MIGLARESE - Phoenix AZ, US David SPETZLER - Paradise Valley AZ, US
International Classification:
C12N 15/115 C12N 15/10 C12Q 1/6883
Abstract:
Methods and compositions are provided to identify oligonucleotides that bind targets of interest. The targets include tissues, cells, circulating biomarkers such as microvesicles, including those derived from various diseases. The oligonucleotides can be used in diagnostic and therapeutic applications.
Methods and compositions are provided to identify oligonucleotide probes that can detect various targets of interest. The targets include microvesicles, microvesicle antigens, and nucleic acids. The target detection may be used to provide a diagnosis, prognosis or theranosis of a medical condition, a disease or a disorder.
Caris Life Sciences
Director, Research and Development
Caris Life Sciences
Senior Research Scientist I
Caris Life Sciences
Research Scientist Ii
Caris Life Sciences Aug 1, 2012 - Nov 2014
Research Scientist I
University of Massachusetts Jan 2010 - Aug 2012
Senior Research Fellow
Education:
Mayo Clinic School of Health Sciences 1999 - 2005
Doctorates, Doctor of Philosophy, Molecular Biology
University of Arizona 1992 - 1995
Bachelors, Bachelor of Science, Biochemistry
Skills:
Protein Chemistry Molecular Biology Biochemistry Mass Spectrometry Assay Development Protein Protein Interactions Hplc Immunoprecipitation Affinity Chromatography Molecular Genetics Protein Expression and Purification Basic and Applied Research Peer Reviewed Publications Invited Speaker at National and International Scientific Conferences Problem Solver Critical Thinker Team Leadership Protein Functional Assays Cross Linking/Nlc Ms/Ms Sec Page Limited Proteolysis Cd Positional Cloning and Mutational Analysis Protein Structure and Function Functional Characterization of Protein Complexes Grantsmanship