Heather Joy Powell

US Patent:

20130266943, Oct 10, 2013

Filed:

Mar 15, 2013

Appl. No.:

13/836137

Inventors:

Heather Powell - Mason OH, US
John Lannutti - Grove City OH, US
Britani Blackstone - Hilliard OH, US

International Classification:

G01N 1/34

US Classification:

435 611, 435 29, 435 612, 435 71, 530356, 528271, 428401, 4284782, 428435, 4284111, 428426

Abstract:

In an aspect, provided is an apparatus for sorting cells. The device may include polymer nanofibers treated with gaseous plasma. The nanofibers may comprise at least one of polycaprolactone and collagen. The gaseous plasma may comprise at least one of CF, oxygen, argon, nitrogen, and air. In a further aspect, provided are methods of sorting cells in a composition. The method may include providing a substrate comprising polymer nanofibers that have been pretreated with a gaseous plasma, contacting the polymer nanofibers with a composition comprising a plurality of cells, and applying a force to the polymer nanofibers. In another aspect, provided are methods of making a device for sorting cells. The method may include applying a composition comprising at least one polymer onto a surface by electrospinning to form polymer nanofibers, and exposing the polymer nanofibers to a gaseous plasma to produce treated polymer nanofibers.