Heather G Stenmark

US Patent:

7115596, Oct 3, 2006

Filed:

Dec 19, 2003

Appl. No.:

10/741056

Inventors:

John A. Wendt - South Lyon MI, US
Heather Stenmark - Chicago IL, US
Hongwei Wu - Buffalo Grove IL, US
Yaping Wang - Acton MA, US
Barbara B. Chen - Northbrook IL, US
Thomas D. Penning - Elmhurst IL, US
Victoria L. Downs - Pinckney MI, US
Mark L. Boys - Brighton MI, US
Mark Russell - Gurnee IL, US
Dale P. Spangler - San Diego CA, US

Assignee:

Pharmacia Corporation - St. Louis MO

International Classification:

A61K 31/55
A61K 31/5025
A61K 31/44
A61K 31/425
A61K 31/36
C07D 401/00
C07D 417/00
C07D 413/00
C07D 471/02
C07D 207/00
C07D 317/46

US Classification:

51421704, 514249, 514303, 514365, 514465, 540597, 544 60, 544124, 544350, 546118, 546122, 5462697, 546290, 548181, 548400, 549435

Abstract:

The present invention relates to a class of compounds represented by the Formula I.

US Patent:

20050043344, Feb 24, 2005

Filed:

Dec 22, 2003

Appl. No.:

10/743354

Inventors:

Mark Boys - Brighton MI, US
Lori Schretzman - East Hanover NJ, US
Michael Tollefson - Dardenne Prairie MO, US
Nizal Chandrakumar - Grafton MA, US
Ish Khanna - Libertyville IL, US
Maria Nguyen - Ann Arbor MI, US
Victoria Downs - Pinckney MI, US
Scott Mohler - Chicago IL, US
Glen Gesicki - Chicago IL, US
Thomas Penning - Elmhurst IL, US
Barbara Chen - Glenview IL, US
Yaping Wang - Acton MA, US
Albert Khilevich - Buffalo Grove IL, US
Bipinchandra Desai - Vernon Hills IL, US
Yi Yu - Glenview IL, US
John Wendt - South Lyon MI, US
Heather Stenmark - Chicago IL, US
Hongwei Wu - Buffalo Grove IL, US
Renee Huff - Park Ridge IL, US
Srinivasan Nagarajan - Chesterfield MO, US
Balekudru Devadas - Chesterfield MO, US
Mark Russell - Gurnee IL, US
Dale Spangler - San Diego CA, US
Mihir Parikh - Chesterfield MO, US

International Classification:

A61K031/4745

US Classification:

514300000

Abstract:

The present invention relates to pharmaceutical compositions comprising compounds of the Formula I, or a pharmaceutically acceptable salt thereof, and methods of selectively inhibiting or antagonizing the αβand/or the αβintegrin without significantly inhibiting the αβintegrin.

US Patent:

6720315, Apr 13, 2004

Filed:

Jun 15, 2001

Appl. No.:

09/882137

Inventors:

Thomas Rogers - Ballwin MO
Michael Clare - Skokie IL
Mark Russell - Grunee IL
James W. Malecha - Libertyville IL
Ish Kumar Khanna - Libertyville IL
Thomas Penning - Elmhurst IL
Srinivasan Raj Nagarajan - Chesterfield MO
Heather Stenmark - Chicago IL

Assignee:

Pharmacia Corporation - Peapack NJ

International Classification:

A61K 3133

US Classification:

514183, 514253, 514277, 514336, 514349, 514351, 514357, 546 1, 546304, 546339, 546329

Abstract:

The present invention relates to a class of compounds represented by the Formula 1. or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of the Formula 1, and methods of selectively inhibiting or antagonizing the and/or the integrin.