Helen L Moore

US Patent:

20020028915, Mar 7, 2002

Filed:

Dec 27, 2000

Appl. No.:

09/748107

Inventors:

Ming-Hui Wei - Germantown MD, US
Jane Ye - Boyds MD, US
Helen Moore - Rockville MD, US
Gennady Merkulov - Baltimore MD, US
Valentina Di Francesco - Rockville MD, US
Ellen Beasley - Darnestown MD, US

International Classification:

C07H021/02
C07H021/04
C07K001/00
C07K014/00
C07K017/00

US Classification:

530/350000, 536/023100

Abstract:

The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the transporter peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the transporter peptides, and methods of identifying modulators of the transporter peptides.

US Patent:

20030143683, Jul 31, 2003

Filed:

Oct 28, 2002

Appl. No.:

10/281346

Inventors:

Ming-Hui Wei - Germantown MD, US
Jane Ye - Boyds MD, US
Helen Moore - Rockville MD, US
Gennady Merkulov - Baltimore MD, US
Valentina Di Francesco - Rockville MD, US
Ellen Beasley - Darnestown MD, US

Assignee:

APPLERA CORPORATION - Norwalk CT

International Classification:

C07K014/47
C12P021/02
C12N005/06
C07H021/04

US Classification:

435/069100, 435/320100, 435/325000, 530/350000, 536/023500

Abstract:

The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the transporter peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the transporter peptides, and methods of identifying modulators of the transporter peptides.

US Patent:

20050066276, Mar 24, 2005

Filed:

Dec 12, 2003

Appl. No.:

10/735606

Inventors:

Helen Moore - Rockville MD, US
Vivien Bonazzi - North Potomac MD, US
Leslie Foster - Germantown MD, US
Mark Gorokhov - Germantown MD, US
Olivier Jojic - Annandale VA, US
Fu Lu - Gaithersburg MD, US
Douglas Mason - Germantown MD, US
Zhen Wang - Vienna VA, US
Richard Wise - Germantown MD, US
Xiangqun Zheng - N. Potomac MD, US
Fei Zhong - Rockville MD, US

International Classification:

G06F003/00
G06F009/00
G06F017/00

US Classification:

715700000

Abstract:

A method and interactive screen system for identifying orthologous genomic regions between two or more species can be provided. The method can involve performing a BLAST search using each of the two or more species against each of the other of the two or more species and identifying the best ortholog matches. The interactive screen system can display one or more of (a) a map viewer which can show genomic sequence information of the two or more species with markers therein, (b) a TA viewer which can show at least one contig and fragments which generated the contig, (c) an evidence viewer which can anotate transcribed regions of the genomic data, (d) a synteny viewer which can show syntenic relationships between the genomic sequence data, (e) a multiple sequence alignment viewer which can show multiple sequence alignments of genomic sequences, and (f) a trace viewer which can show single nucleotides in genomic sequences.