Hemayet H Ullah

US Patent:

20040187176, Sep 23, 2004

Filed:

Jun 24, 2003

Appl. No.:

10/602898

Inventors:

Douglas Boyes - Chapel Hill NC, US
Keith Davis - Durham NC, US
Alan Jones - Chapel Hill NC, US
Hemayet Ullah - Chapel Hill NC, US
Rao Mulpuri - Apex NC, US
Ani Chatterjee - San Francisco CA, US
Mary Ward - Gaithersburg MD, US

International Classification:

A01H001/00
C12N015/82

US Classification:

800/287000

Abstract:

The invention provides methods for improving plant agronomic traits by altering the expression or activity of plant G-protein alpha and beta subunits that are GPA1 or AGB1 orthologs. The invention also provides such transgenic plants with improved agronomic traits. One embodiment of the invention includes methods for modulating the expression or activity of a plant G-protein beta subunit that is an AGB1 ortholog to alter one or more of the following: the time to reach and duration of flowering, fruit yield, root biomass, seed size, seed shape, plant size, and the number of stem branches. The present invention also encompasses methods for modulating the expression or activity of a plant G-protein alpha subunit that is a GPA1 ortholog to alter one or more of the following: the duration of flowering, fruit and seed yield, plant size, seed size, and seed shape. The compositions of the invention include transgenic plants, and seed thereof, particularly transgenic plants that are dicots, members of the genus Brassica, trees, or gymnosperms.

US Patent:

20200297699, Sep 24, 2020

Filed:

Mar 27, 2017

Appl. No.:

16/088392

Inventors:

Hemayet ULLAH - North Potomac MD, US
Sivanesan DAKSHANAMURTHY - Herndon VA, US

International Classification:

A61K 31/4196

Abstract:

A method effective in treating a viral infection involves administering a therapeutically effective amount of at least one compound capable of inhibiting expression of at least a portion of a virus genome containing an internal ribosomal entry site, or a pharmaceutically acceptable salt thereof. The compound has an azole moiety comprising a five member heterocyclic ring containing at least one nitrogen atom, a hydrophobic moiety bonded to the heterocyclic ring of the azole, and a donor/acceptor moiety bonded to the heterocyclic ring having at least one of hydrogen bond donor and a hydrogen bond acceptor.