Henry L Stone

US Patent:

7279163, Oct 9, 2007

Filed:

Mar 21, 2002

Appl. No.:

10/101943

Inventors:

Petter S. Holt - Colbert GA, US
Cam R. Greene - Jefferson GA, US
Henry D. Stone - Colbert GA, US

Assignee:

The United States of America, as represented by the Secretary of Agriculture - Washington DC

International Classification:

A61K 8/00
A61K 39/00
A01N 65/00

US Classification:

4241841, 424 701, 424 7019, 514 74

Abstract:

Oil-in-Water emulsion vaccines induce higher biliary IgA responses which decrease mucosal/internal organ invasion and fecal shedding, increase specific activity of serum IgG subpopulations, and increase the relative avidity index of serum IgG subpopulations, resulting in increased protection from disease in animals.

US Patent:

7914801, Mar 29, 2011

Filed:

Jul 8, 2004

Appl. No.:

10/887277

Inventors:

Peter S. Holt - Colbert GA, US
Cam R. Greene - Jefferson GA, US
Henry D. Stone - Colbert GA, US

Assignee:

The United States of America as represented by the Secretary of Agriculture - Washington DC

International Classification:

A61K 45/00
A61K 8/00
A61K 8/30
A61K 9/00
A61K 9/50

US Classification:

4242781, 424 7019, 424 7031, 424400, 424502

Abstract:

Water-in-oil priming emulsion vaccines increase the titers and/or avidity indexes of antibodies following a second dose of a commercial or experimental vaccine resulting in increased protection for disease in animal.

US Patent:

8440447, May 14, 2013

Filed:

May 31, 2006

Appl. No.:

11/445091

Inventors:

Henry Stone - Colbert GA, US
Cam Greene - Jefferson GA, US
Peter Holt - Colbert GA, US
Richard Gast - Watkinsville GA, US
Kunho Seo - Gaithersburg MD, US

Assignee:

The United States of America, as represented by the Secretary of Agriculture - Washington DC

International Classification:

C12N 7/02
C12Q 1/70

US Classification:

435239, 435 5

Abstract:

A method for extraction and concentration of antibodies, antigens, bacteria and virus from biological samples. The method also provides a preparation that is suitable for use as a vaccine. The method includes the addition of liquid carboxylic acids and a centrifugation step.

US Patent:

20040038197, Feb 26, 2004

Filed:

Aug 22, 2002

Appl. No.:

10/225419

Inventors:

Henry Stone - Colbert GA, US
Cam Greene - Jefferson GA, US
Peter Holt - Colbert GA, US
Richard Gast - Watkinsville GA, US
Kunho Seo - Gaithersburg MD, US

International Classification:

C12Q001/70
G01N033/554
G01N033/569

US Classification:

435/005000, 435/007320

Abstract:

A method for extraction and concentration of antibodies, antigens, bacteria and virus from biological samples. The method also provides a preparation that is suitable for use as a vaccine. The method includes the addition of liquid carboxylic acids and a centrifugation step.

US Patent:

57501017, May 12, 1998

Filed:

Sep 15, 1995

Appl. No.:

8/530698

Inventors:

Henry D. Stone - Winterville GA

Assignee:

The United States of America, as represented by the Secretary of
Agriculture - Washington DC

International Classification:

C12N 500
C12N 1500
A61K 4800

US Classification:

424 852

Abstract:

Avian diseases, particularly those which threaten birds early in life, are controlled by embryonal vaccination using oil emulsion vaccines. The site of inoculation is the albumin end of the egg via entry through the air cell end of the egg.

US Patent:

57441375, Apr 28, 1998

Filed:

Feb 6, 1995

Appl. No.:

8/384184

Inventors:

Henry D. Stone - Winterville GA

Assignee:

The United States of America as represented by the Secretary of the
Agriculture - Washington DC

International Classification:

A61K 3900
A61K 966
A61K 700
A01N 6500

US Classification:

4241841

Abstract:

A composition of a mixture of nonionic surfactants in water-in-oil emulsion vaccines allows the use of animal, vegetable, and synthetic oils as well as mineral oil and pristane. These non-mineral oil vaccines are as efficacious as mineral oil-containing vaccines without the problems associated with the use of mineral oil.

US Patent:

61267228, Oct 3, 2000

Filed:

Jul 28, 1998

Appl. No.:

9/122850

Inventors:

Bailey W. Mitchell - Watkinsville GA
Henry D. Stone - Winterville GA

Assignee:

The United States of America as represented by the Secretary of
Agriculture - Washington DC

International Classification:

B03C 3019

US Classification:

95 57

Abstract:

A dust reduction system for reducing airborne contaminants such as, for example, dust, smoke, microorganisms, etc. , includes at least one ion generator made up of at least one ionizer bar and a ground plane which is parallel and proximate to at least one bar. The system can also include a dust collection device such as a tray containing an aqueous composition optionally containing a degreaser, and/or a metal sheet with a water rinse system, and/or the surfaces of a room-sized enclosed space. The system can be applied to any enclosed space where it is desired to obtain high efficiency reduction of airborne dust and microorganisms. The system is especially useful in poultry production and processing areas such as hatching cabinets, throwing rooms, and controlled environment poultry rearing rooms.

US Patent:

58173200, Oct 6, 1998

Filed:

Sep 27, 1996

Appl. No.:

8/722959

Inventors:

Henry D. Stone - Winterville GA

Assignee:

The United States of America as represented by the Secretary of the
Agriculture - Washington DC

International Classification:

A01N 3718

US Classification:

4242781

Abstract:

Avian diseases, particularly those which threaten birds early in life, are controlled by embryonal vaccination using water-in-oil-in-water emulsion vaccines. The site of inoculation is the albumin end of the egg via entry through the air cell end of the egg.