Hiram Ralph Snodgrass

US Patent:

55852696, Dec 17, 1996

Filed:

Jun 2, 1994

Appl. No.:

8/252626

Inventors:

H. Shelton Earp - Chapel Hill NC
Doug Graham - Chapel Hill NC
Thomas L. Dawson - Chapel Hill NC
David L. Mullaney - Middletown CT
Hiram R. Snodgrass - Powell OH

Assignee:

The University of North Carolina at Chapel Hill - Chapel Hill NC

International Classification:

C07K 14705
C07K 1900
C12N 1512
C12N 1562

US Classification:

4352523

Abstract:

Isolated DNAs encoding a mammalian c-mer receptor which exhibits c-mer protooncogene activity and tyrosine kinase activity are disclosed. Also disclosed are vectors containing such DNAs, host cells containing such DNAs, c-mer receptor proteins, and soluble axl receptors, chimeric proteins including the extracellular domain of the c-mer receptor and DNAs encoding such chimeric proteins, and antibodies which specifically bind the c-mer receptor.