Hongfeng Andy Chen from 539 Penn Manor Dr, Newark, DE 19711, age 59

Resumes

Senior Vice President And General Manager For Manufacturing

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Location:

Wilmington, DE

Industry:

Pharmaceuticals

Work:

Wilmington PharmaTech Company since Oct 2009
Vice President of Process Chemistry
Wilmington PharmaTech Apr 2008 - Sep 2009
Director of Process Development
Johnson & Johnson PRD 2004 - 2008
scientist
University of Pittsburgh 2001 - 2004
Postdoctoral Research Associate
Institute of Photographic and Photochemistry 1989 - 1996
research assistant

Education:

University of Arizona 1998 - 2002
Doctor of Philosophy (PhD), Organic Chemistry The University of Connecticut 1996 - 1998
PhD student, Organic Chemistry Peking University 1985 - 1989
BS, Chemistry

Skills:

Chemistry
Organic Chemistry
Drug Development
Hplc
Pharmaceutical Industry
Analytical Chemistry
Technology Transfer
Chromatography
Organic Synthesis
Gmp
Lc Ms
Nmr
R&D
Glp
Lifesciences
Purification
Mass Spectrometry

Us Patents

Process For The Preparation Of Substituted Pyrimidine Derivatives
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US Patent:

8309720, Nov 13, 2012
Filed:

Jun 29, 2009
Appl. No.:

12/459229
Inventors:

Sergio Cesco-Cancian - Bethlehem PA, US
Hongfeng Chen - Wilmington DE, US
Jeffrey S. Grimm - Somerville NJ, US
Neelakandha S. Mani - San Diego CA, US
Christopher M. Mapes - La Mesa CA, US
David C. Palmer - Doylestown PA, US
Daniel J. Pippel - Del Mar CA, US
Kirk L. Sorgi - Doylestown PA, US
Tong Xiao - Edison NJ, US
Assignee:

Janssen Pharmaceutica NV - Beerse
International Classification:

C07D 211/06
C07D 211/30
US Classification:

544330, 546246, 546248
Abstract:

The present invention is directed to processes for the preparation of substituted pyrimidine derivatives, useful as intermediates in the synthesis of histamine Hreceptor modulators, and to intermediates in H4 modulator synthesis.

Process For Preparing Substituted Diaminopyrimidine Oximes
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US Patent:

8278446, Oct 2, 2012
Filed:

Jun 21, 2007
Appl. No.:

11/766257
Inventors:

Hongfeng Chen - Somerville NJ, US
Peter J. Connolly - New Providence NJ, US
Kirk L. Sorgi - Doylestown PA, US
Anusuya Choudhury - Churchville PA, US
Christopher N. Nilsen - Branchburg NJ, US
Assignee:

Janssen Pharmaceutica N.V. - Beerse
International Classification:

C07D 239/48
C07D 239/50
C07D 401/12
C07D 401/14
C07D 403/12
C07D 403/14
US Classification:

544326, 544328
Abstract:

The present invention is directed to a process for chemoselective substitution on a halopyrimidine carboxaldehyde having multiple reactive sites and subsequent stereoselective oxime formation.

Process For The Preparation Of Substituted Pyrimidine Derivatives
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US Patent:

20130053561, Feb 28, 2013
Filed:

Oct 29, 2012
Appl. No.:

13/663233
Inventors:

Janssen Pharmaceutica NV - New Brunswick NJ, US
Hongfeng CHEN - Somerville NJ, US
Jeffrey S. GRIMM - Somerville NJ, US
Neelakandha S. MANI - San Diego CA, US
Christopher M. MAPES - La Jolla CA, US
David C. PALMER - Doylestown PA, US
Daniel J. PIPPEL - Del Mar CA, US
Kirk L. SORGI - Doylestown PA, US
Tong XIAO - Edison NJ, US
Assignee:

Janssen Pharmaceutica NV - New Brunswick NJ
International Classification:

C07D 401/12
US Classification:

544330
Abstract:

The present invention is directed to processes for the preparation of substituted pyrimidine derivatives, useful as intermediates in the synthesis of histamine Hreceptor modulators, and to intermediates in Hmodulator synthesis.

Process For The Preparation Of Substituted Pyrimidine Derivatives
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US Patent:

20130225816, Aug 29, 2013
Filed:

Mar 15, 2013
Appl. No.:

13/844227
Inventors:

Janssen Pharmaceutica NV - , US
Hongfeng Chen - Somerville NJ, US
Jeffrey S. Grimm - Somerville NJ, US
Neelakandha S. Mani - San Diego CA, US
Christopher M. Mapes - La Jolla CA, US
David C. Palmer - Doylestown PA, US
Daniel J. Pippel - Del Mar CA, US
Kirk L. Sorgi - Doylestown PA, US
Tong Xiao - Edison NJ, US
Assignee:

Janssen Pharmaceutica NV - New Brunswick NJ
International Classification:

C07D 401/12
US Classification:

544330
Abstract:

The present invention is directed to processes for the preparation of substituted pyrimidine derivatives, useful as intermediates in the synthesis of histamine Hreceptor modulators, and to intermediates in Hmodulator synthesis.

Process For The Preparation Of Substituted Pyrimidine Derivatives
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US Patent:

20140066624, Mar 6, 2014
Filed:

Nov 11, 2013
Appl. No.:

14/076955
Inventors:

Hongfeng Chen - Somerville NJ, US
Jeffrey S. Grimm - Somerville NJ, US
Neelakandha S. Mani - San Diego CA, US
Christopher M. Mapes - La Jolla CA, US
David C. Palmer - Doylestown PA, US
Daniel J. Pippel - Del Mar CA, US
Kirk L. Sorgi - Doylestown PA, US
Tong Xiao - Edison NJ, US
Assignee:

Janssen Pharmaceutica NV - New Brunswick NJ
International Classification:

C07D 401/12
US Classification:

544330
Abstract:

The present invention is directed to processes for the preparation of substituted pyrimidine derivatives, useful as intermediates in the synthesis of histamine Hreceptor modulators, and to intermediates in H4 modulator synthesis.

Process For The Preparation Of Substituted Pyrimidine Derivatives
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US Patent:

20140073795, Mar 13, 2014
Filed:

Nov 13, 2013
Appl. No.:

14/079358
Inventors:

Hongfeng Chen - Somerville NJ, US
Jeffrey S. Grimm - Somerville NJ, US
Neelakandha S. Mani - San Diego CA, US
Christopher M. Mapes - La Jolla CA, US
David C. Palmer - Doylestown PA, US
Daniel J. Pippel - Del Mar CA, US
Kirk L. Sorgi - Doylestown PA, US
Tong Xiao - Edison NJ, US
Assignee:

Janssen Pharmaceutica NV - New Brunswick NJ
International Classification:

C07D 211/26
US Classification:

546231
Abstract:

The present invention is directed to processes for the preparation of substituted pyrimidine derivatives, useful as intermediates in the synthesis of histamine Hreceptor modulators, and to intermediates in H4 modulator synthesis.

Process For The Preparation Of Substituted Pyrimidine Derivatives
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US Patent:

20140121374, May 1, 2014
Filed:

Nov 12, 2013
Appl. No.:

14/078153
Inventors:

- New Brunswick NJ, US
Hongfeng Chen - Somerville NJ, US
Jeffrey S. Grimm - Somerville NJ, US
Neelakandha S. Mani - San Diego CA, US
Daniel J. Pippel - Del Mar CA, US
Assignee:

Janssen Pharmaceutica NV - New Brunswick NJ
International Classification:

C07D 401/12
US Classification:

544330
Abstract:

The present invention is directed to processes for the preparation of substituted pyrimidine derivatives, useful as intermediates in the synthesis of histamine Hreceptor modulators, and to intermediates in H4 modulator synthesis.