Hossain H Saneii

US Patent:

6358479, Mar 19, 2002

Filed:

May 30, 2000

Appl. No.:

09/580614

Inventors:

Dominic Frisina - Louisville KY
Michael R. Ferriell - Louisville KY
Hossain Saneii - Louisville KY

Assignee:

Advanced ChemTech, Inc. - Louisville KY

International Classification:

B01J 1900

US Classification:

422131, 422103, 422104, 422101, 422130

Abstract:

The reaction block assembly of the invention comprises a reaction block in which are disposed a plurality of reaction wells. Influent and effluent ducts open at the upper face of the reaction block adjacent each of the reaction wells. These ducts provide communication between each reaction well and a source of reagents and gases and with waste removal means for removal of effluent from the reaction wells. A membrane sheet overlies the upper face of the reaction block to define a pneumatic valve to open and close the duct openings each of the reaction wells to control the input of reagents and gases and effluent flow from the reaction wells. The reaction block assembly preferably includes a temperature control block that underlies the reaction block for control of the temperature in the reaction wells. A waste block underlies the reaction block or, if used, the temperature control block. The effluent ducts from the reaction wells communicate with the waste block for removal of reaction well effluent from the reaction block assembly.

US Patent:

7048892, May 23, 2006

Filed:

Jul 24, 2002

Appl. No.:

10/202453

Inventors:

James Shannon - Louisville KY, US
Michael Ferriell - Louisville KY, US
Hossain Saneii - Louisville KY, US

International Classification:

B01L 3/02

US Classification:

422100, 422102, 422104

Abstract:

A system for automated high-pressure synthesis and more particularly a high-pressure reactor assembly comprises a reaction block and a pressure manifold for the introduction of pressure to the reaction wells of a reaction block. The reactor includes one or more pressure resistant reaction wells or vessels disposed in the reaction block.

US Patent:

57469822, May 5, 1998

Filed:

Feb 29, 1996

Appl. No.:

8/609968

Inventors:

Hossain Saneii - Louisville KY
Mohammad R. Boroomand - Louisville KY
Michael R. Ferriell - Louisville KY

Assignee:

Advanced ChemTech, Inc. - Louisville KY

International Classification:

C08F 202
B01J 1400

US Classification:

422134

Abstract:

Apparatus for the synthesis of chemical compounds consists of a housing having a top, front, side and rear walls surrounding and enclosing a reaction table. A track on the rear wall of the housing carries a pair of extending arms on each of which is movably mounted a vertically extendible probe for positioning at various locations over the reaction table. At least on control syringe communicates between the probe and containers for system fluids. A programmable controller is provided for control of the syringe and probes. A reaction block on the reaction table consists of a body having an upper portion and a lower portion and an upper and lower surface and a multiplicity of reaction wells for carrying out the synthesis. Each reaction well is closed at its lower end and open to the upper surface. A flushing conduit is located adjacent each of the well and is in fluid communication with the closed lower end of the reaction well.

US Patent:

48807818, Nov 14, 1989

Filed:

Jan 20, 1988

Appl. No.:

7/147073

Inventors:

Jackson B. Hester - Galesburg MI
Suvit Thaisrivongs - Portage MI
Tomi K. Sawyer - Kalamazoo MI
Ruth E. TenBrink - Kalamazoo MI
Hossain H. Saneii - Louisville KY
Heinrich J. Schostarez - Portage MI
Donald T. Pals - Portage MI

Assignee:

The Upjohn Company - Kalamazoo MI

International Classification:

A61K 3743
C07K 706
C07K 508
C07K 510
C07K 506

US Classification:

514 18

Abstract:

The present invention provides novel renin-inhibiting peptides and novel processes and intermediates for the preparation of both novel and known renin-inhibiting peptide analogs. Such inhibitors are useful for the diagnosis and control of renin-dependent hypertension.