Howard M Murad

US Patent:

6358539, Mar 19, 2002

Filed:

Aug 18, 2000

Appl. No.:

09/641376

Inventors:

Howard Murad - Marina del Rey CA 90292

International Classification:

A61K 3578

US Classification:

424725, 424728, 424752, 514860

Abstract:

Compositions and methods for reducing or eliminating the appearance of cellulite. The method involves administering to a patient in need of treatment therapeutically effective amounts of a sugar compound that is converted to a glycosaminoglycan in the patient in an amount sufficient to thicken the skin, a primary antioxidant component in an amount sufficient to substantially inhibit the formation of collagenase and elastase, at least one amino acid component in an amount sufficient to assist in the thickening of the skin, and at least one transition metal component in an amount effective to bind collagen and elastic fibers and thicken skin so as to reduce or eliminate the appearance of cellulite. A preferred method of treatment further includes administering the components above in conjunction with a vascular dilator to improve blood supply to the skin and/or a fat burner to reduce absorption or digestion of fat in the digestive tract or to prevent the production of fat. The compositions and methods may optionally include chromium picolinate to facilitate entry of sugar into cells to improve fat metabolism.

US Patent:

6515007, Feb 4, 2003

Filed:

Aug 3, 2001

Appl. No.:

09/920729

Inventors:

Howard Murad - Marina del Rey CA 90292

International Classification:

A61K 31415

US Classification:

514396, 514460, 514557, 514721, 514725, 514880, 514881

Abstract:

This application relates to a pharmaceutical composition for the prevention, treatment, and management of scalp conditions, such as dandruff, seborrheic dermatitis, psoriasis, folliculitis, and hair thinning including a therapeutically effective amount of an acidic component of a hydroxyacid or tannic acid, or a pharmaceutically acceptable salt thereof. A preferred anti-dandruff composition and method of managing dandruff includes a therapeutically effective amount of the acid component, a vitamin A component, and an anti-growth agent. A preferred anti-hair thinning composition and method of managing thinning hair includes a therapeutically effective amount of the acidic component, a niacin component present in an amount sufficient to locally increase blood circulation, and a 5- reductase inhibitor. The invention also relates to a method of treating chemically processed hair by administering to a patient an amount of an acidic component of a hydroxy acid or tannic acid, or a pharmaceutically acceptable salt thereof, in an amount sufficient to essentially close the cuticle and inhibit modification of the chemically processed hair.

US Patent:

6630163, Oct 7, 2003

Filed:

Feb 10, 2000

Appl. No.:

09/501218

Inventors:

Howard Murad - Marina del Rey CA 90292

International Classification:

A61K 920

US Classification:

424464, 424401, 424725, 424735, 424736, 424744, 424765, 424768, 424 59

Abstract:

This application relates to methods for treating dermatological disorders. The methods include administering a therapeutically effective amount of at least one fruit extract in an amount sufficient to neutralize free radicals; and a pharmaceutically acceptable carrier. Preferred fruit extracts include extracts from apricots, apples, peaches, pears, pineapples, papayas, pomegranates, cherries, kiwis, tangerines and oranges. The most preferred extract is extract from pomegranate.

US Patent:

6673374, Jan 6, 2004

Filed:

Sep 17, 2001

Appl. No.:

09/953431

Inventors:

Howard Murad - Marina del Rey CA 90292

International Classification:

A61K 3340

US Classification:

424616, 514248, 514616, 514714, 514739

Abstract:

This application relates to a pharmaceutical composition and methods for treating inflammatory skin conditions. The compositions include hydrogen peroxide, one or more moisturizing agents, and an anti-inflammatory agent. The pharmaceutical compositions may optionally include one or more exfoliants. The compositions can be used to treat inflammatory skin conditions such as dermatitis, including, but not limited to seborrheic dermatitis, nummular dermatitis, contact dermatitis, atopic dermatitis, exfoliative dermatitis, perioral dermatitis, and stasis dermatitis; psoriasis; folliculitis; rosacea; acne; impetigo; erysipelas; paronychia, erythrasma; and eczema.

US Patent:

6676977, Jan 13, 2004

Filed:

Jan 22, 2002

Appl. No.:

10/051189

Inventors:

Howard Murad - Marina del Rey CA 90292

International Classification:

A01N 6500

US Classification:

424728, 424736, 424752, 424765, 424766, 424777, 424725, 514860

Abstract:

Compositions and methods for reducing or eliminating the appearance of cellulite. The method involves administering to a patient in need of treatment therapeutically effective amounts of a sugar compound that is converted to a glycosaminoglycan in the patient in an amount sufficient to thicken the skin, a primary antioxidant component in an amount sufficient to substantially inhibit the formation of collagenase and elastase, at least one amino acid component in an amount sufficient to assist in the thickening of the skin, and at least one transition metal component in an amount effective to bind collagen and elastic fibers and thicken skin so as to reduce or eliminate the appearance of cellulite. A preferred method of treatment further includes administering the components above in conjunction with a vascular dilator to improve blood supply to the skin and/or a fat burner to reduce absorption or digestion of fat in the digestive tract or to prevent the production of fat. The compositions and methods may optionally include chromium picolinate to facilitate entry of sugar into cells to improve fat metabolism.

US Patent:

6800292, Oct 5, 2004

Filed:

Feb 10, 2000

Appl. No.:

09/501217

Inventors:

Howard Murad - Marina del Rey CA 90292

International Classification:

A61K 700

US Classification:

424401, 424725, 424726, 424731, 424728, 424729, 424732, 424735, 424764, 424771

Abstract:

This application relates to dermatological agents for treating dermatological disorders. The dermatological agents include a therapeutically effective amount of at least one fruit extract in an amount sufficient to neutralize free radicals, a moisturizing agent in an amount sufficient to facilitate hydration of the skin, and a pharmaceutically acceptable carrier. Preferred fruit extracts include extracts from apricots, apples, peaches, pears, pineapples, papayas, pomegranates, cherries, kiwis, tangerines, grapes, and oranges. The most preferred extract is extract from pomegranate.

US Patent:

20020127256, Sep 12, 2002

Filed:

Feb 25, 2002

Appl. No.:

10/080717

Inventors:

Howard Murad - Marina del Rey CA, US

International Classification:

A61K035/78
A61K031/7024
A61K031/192
A61K031/198
A61K007/00

US Classification:

424/401000, 424/768000, 424/776000, 514/023000, 514/054000, 514/557000, 514/570000, 514/561000, 514/021000

Abstract:

The invention relates to dermatological agents and methods for treating dermatological disorders. The dermatological agents include a therapeutically effective amount of at least one acid selected from ellagic acid, ferrulic acid, caffeic acid, or tannic acid in an amount sufficient to strengthen cell membranes in the skin. The at least one acid is preferably combined with at least one of a moisturizing agent, an anti-inflammatory component, an immunity boosting component or an additional anti-oxidant, and a pharmaceutically acceptable carrier.

US Patent:

20030007939, Jan 9, 2003

Filed:

Feb 20, 2002

Appl. No.:

10/077928

Inventors:

Howard Murad - Marina del Rey CA, US

International Classification:

A61K033/40
A61K007/04
A61K007/06

US Classification:

424/061000, 424/070100, 424/616000

Abstract:

Pharmaceutical composition including hydrogen peroxide and at least one other dermatological agent. The pharmaceutical compositions cleanse the dermatological surfaces and facilitate penetration of the at least one other dermatological for the treatment of a dermatological condition. The pharmaceutical compositions are useful in methods of treating, preventing, and managing skin conditions, scalp conditions, hair conditions, and nail conditions.