Hui Qi Huang

US Patent:

7109354, Sep 19, 2006

Filed:

May 28, 2003

Appl. No.:

10/445817

Inventors:

Nalin Subasinghe - West Chester PA, US
Ehab Khalil - West Chester PA, US
Kristi Leonard - West Chester PA, US
Farah Ali - Exton PA, US
Heather Rae Hufnagel - Glenmoore PA, US
Jeremy M. Travins - Newtown Square PA, US
Shelley K. Ballentine - Lansdale PA, US
Kenneth T. Wilson - West Grove PA, US
Maxwell D. Cummings - Wayne PA, US
Wenxi Pan - Glenmoore PA, US
Joan Gushue - Collegeville PA, US
Sanath Meegalla - Boothwyn PA, US
Mark Wall - Harleysville PA, US
Jinsheng Chen - Exton PA, US
M. Jonathan Rudolph - Exton PA, US
Hui Huang - Belle Mead NJ, US

Assignee:

3-Dimensional Pharmaceuticals, Inc. - Yardley PA

International Classification:

C07D 333/02
C07D 333/32

US Classification:

549 29, 549 64, 549 70, 549 83

Abstract:

Disclosed is a method for treating the symptoms of an acute or chronic disorder mediated by the classical pathway of the complement cascade, comprising administering to a mammal in need of such treatment a therapeutically effective amount of a compound of Formula I.

US Patent:

7335153, Feb 26, 2008

Filed:

Jul 9, 2002

Appl. No.:

10/192352

Inventors:

Michael Seul - Fanwood NJ, US
Chiu Wo Chau - Edison NJ, US
Hui Huang - Piscataway NJ, US
Sukanta Banerjee - North Brunswick NJ, US
Jiacheng Yang - Hillsboro NJ, US
Ye Hong - Piscataway NJ, US

Assignee:

Bio Array Solutions Ltd. - Warren NJ

International Classification:

C40B 20/02

US Classification:

506 3, 435 6

Abstract:

This invention provides high unit density arrays of microparticles and methods of assembling such arrays. The microparticles in the arrays may be functionalized with chemical or biological entities specific to a given target analyte. The high unit density arrays of this invention are formed on chips which may be combined to form multichip arrays according to the methods described herein. The chips and/or multichip arrays of this invention are useful for chemical and biological assays.

US Patent:

7452565, Nov 18, 2008

Filed:

Jun 13, 2004

Appl. No.:

10/868451

Inventors:

Sukanta Banerjee - North Brunswick NJ, US
Hui Huang - Piscataway NJ, US

International Classification:

B05D 3/00

US Classification:

427 21, 435 6, 435 71, 435 792

Abstract:

Disclosed are two different approaches for immobilization of beads on a substrate, one of which involves forming a bead-nanoparticle composite by cross-linking of the bead mixture with nanoparticles. The other method involves surface modification of the substrate, using multi-layered polyelectrolytes. With either method, the beads are immobilized on the substrate in a manner suitable for viewing, as when the beads are used in assays and need to be analyzed following the assay. Different designs of depressions are also disclosed, some of which are suitable for holding beads in place without any deposition of nanoparticles or polyelectrolytes.

US Patent:

7550474, Jun 23, 2009

Filed:

Apr 1, 2004

Appl. No.:

10/816544

Inventors:

Kevin D. Kreutter - Plainsboro NJ, US
Lily Lee - New York NY, US
Tianbao Lu - Churchville PA, US
Venkatraman Mohan - Plainsboro NJ, US
Sharmila Patel - Jamison PA, US
Hui Huang - Monroe NJ, US
Guozhang Xu - Langhorne PA, US
Mark Fitzgerald - Atco NJ, US

Assignee:

Johnson & Johnson Pharmaceuticals Research & Development, L.L.C. - Raritan NJ

International Classification:

A61K 31/435
C07D 221/02
C07D 335/00
C07D 309/00
C07C 321/00

US Classification:

514277, 546112, 546152, 549 13, 549356, 564162

Abstract:

Phenyl acetamide compounds are described, including compounds of Formula I:.

US Patent:

7642270, Jan 5, 2010

Filed:

Sep 12, 2006

Appl. No.:

11/519611

Inventors:

Mark R. Player - Phoenixville PA, US
Hui Huang - Monroe Township NJ, US
Daniel A. Hutta - Belle Mead NJ, US
Renee L. DesJarlais - Saint Davids PA, US

Assignee:

Janssen Pharmaceutica N.V. - Beerse

International Classification:

A61K 31/44
C07D 471/06

US Classification:

514303, 544279

Abstract:

The invention addresses the current need for selective and potent protein tyrosine kinase inhibitors by providing potent inhibitors of c-fms kinase. The invention is directed to the novel compounds of Formula I:.

US Patent:

7728003, Jun 1, 2010

Filed:

Sep 12, 2006

Appl. No.:

11/519662

Inventors:

Mark R. Player - Phoenixville PA, US
Hui Huang - Monroe Township NJ, US
Hu Huaping - Pennington NJ, US
Renee L. DesJarlais - Saint Davids PA, US

Assignee:

Janssen Pharmaceutica N.V. - Beerse

International Classification:

A61K 31/44
C07D 471/04

US Classification:

514303, 544279

Abstract:

The invention addresses the current need for selective and potent protein tyrosine kinase inhibitors by providing potent inhibitors of c-fms kinase. The invention is directed to the novel compounds of Formula I:.

US Patent:

7842649, Nov 30, 2010

Filed:

Oct 18, 2007

Appl. No.:

11/874355

Inventors:

Michael Seul - Fanwood NJ, US
Chiu Wo Chau - Edison NJ, US
Hui Huang - Piscataway NJ, US
Sukanta Banerjee - North Brunswick NJ, US
Jiacheng Yang - Hillsboro NJ, US
Ye Hong - Piscataway NJ, US

Assignee:

BioArray Solutions, Ltd. - Warren NJ

International Classification:

C40B 50/00

US Classification:

506 23, 506 7, 506 13

Abstract:

This invention provides high unit density arrays of microparticles and methods of assembling such arrays. The microparticles in the arrays may be functionalized with chemical or biological entities specific to a given target analyte. The high unit density arrays of this invention are formed on chips which may be combined to form multichip arrays according to the methods described herein. The chips and/or multichip arrays of this invention are useful for chemical and biological assays.

US Patent:

20110098201, Apr 28, 2011

Filed:

Oct 22, 2010

Appl. No.:

12/910468

Inventors:

Michael Seul - Fanwood NJ, US
Chiu Wo Chau - Edison NJ, US
Hui Huang - Piscataway NJ, US
Sukanta Banerjee - Pennington NJ, US
Jiacheng Yang - Hillsboro NJ, US
Ye Hong - Piscataway NJ, US

Assignee:

BioArray Solutions, Ltd. - Warren NJ

International Classification:

C40B 50/18

US Classification:

506 32

Abstract:

This invention provides high unit density arrays of microparticles and methods of assembling such arrays. The microparticles in the arrays may be functionalized with chemical or biological entities specific to a given target analyte. The high unit density arrays of this invention are formed on chips which may be combined to form multichip arrays according to the methods described herein. The chips and/or multichip arrays of this invention are useful for chemical and biological assays.