Jean Gudas - Pacific Palisades CA, US Aya Jakobovits - Beverly Hills CA, US Xiao-Chi Jia - Los Angeles CA, US Robert Kendall Morrison - Santa Monica CA, US Karen Jane Meyrick Morrison - Santa Monica CA, US Hui Shao - Los Angeles CA, US Pia M. Challita-Eid - Encino CA, US Arthur B. Raitano - Los Angeles CA, US
Assignee:
Agensys, Inc. - Santa Monica CA
International Classification:
C07K 16/00 C07K 16/30 C12P 21/08
US Classification:
5303881, 5303888, 5303911, 5303913, 5303917
Abstract:
Antibodies and molecules derived therefrom that bind to novel PSCA protein, and variants thereof, are described wherein PSCA exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, PSCA provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The PSCA gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with PSCA can be used in active or passive immunization.
Antibodies And Related Molecules That Bind To Psca Proteins
Jean Gudas - Los Angeles CA, US Aya Jakobovits - Beverly Hills CA, US Xiao-chi Jia - Los Angeles CA, US Robert Kendall Morrison - Santa Monica CA, US Karen Jane Meyrick Morrison - Santa Monica CA, US Hui Shao - Los Angeles CA, US Pia M. Challita-Eid - Encino CA, US Arthur B. Raitano - Los Angeles CA, US
Antibodies and molecules derived therefrom that bind to novel PSCA protein, and variants thereof, are described wherein PSCA exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, PSCA provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The PSCA gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with PSCA can be used in active or passive immunization.
Antibodies That Bind To Psca Proteins For Diagnosis Of Cancer
Jean Gudas - Los Angeles CA, US Aya Jakobovits - Beverly Hills CA, US Xiao-chi Jia - Los Angeles CA, US Robert Kendall Morrison - Santa Monica CA, US Karen Jane Meyrick Morrison - Santa Monica CA, US Hui Shao - Los Angeles CA, US Pia M. Challita-Eid - Encino CA, US Arthur B. Raitano - Los Alamitos CA, US
Antibodies and molecules derived therefrom that bind to novel PSCA protein, and variants thereof, are described wherein PSCA exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, PSCA provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The PSCA gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with PSCA can be used in active or passive immunization.
Antibodies That Bind To Psca Proteins For Diagnosis Of Cancer
Jean GUDAS - Los Angeles CA, US Aya Jakobovits - Beverly Hills CA, US Xiao-chi Jia - Los Angeles CA, US Robert Kendall Morrison - Santa Monica CA, US Karen Jane Meyrick Morrison - Santa Monica CA, US Hui Shao - Los Angeles CA, US Pia M. Challita-Eid - Encino CA, US Arthur B. Raitano - Los Alamitos CA, US
International Classification:
C07K 16/30
US Classification:
5303879
Abstract:
Antibodies and molecules derived therefrom that bind to novel PSCA protein, and variants thereof, are described wherein PSCA exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, PSCA provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The PSCA gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with PSCA can be used in active or passive immunization.
Samuel Roberts Noble since Jan 2009
Senior Research Associate
The University of Texas Medical School Jan 2007 - Jan 2009
Research Associate
Samuel Roberts Noble Jan 2004 - Jan 2007
Postdoctoral Fellow
Education:
Molecular Biology and Biochemistry, Institute of Biophysics, Chinese Academy of Sciences
PhD, Molecular Biology and Biochemistry
Polymer Science and engineering
B.S, Chemistry
Skills:
Biochemistry Protein Chemistry Biophysics X-ray crystallography Isothermal Titration Calorimetry (ITC) Immunoblot assay AKTA purification system Protein structure determination Protein–ligand docking PCR and RT-PCR amplification Subcloning and TA cloning Site-directed mutagenesis DNA/RNA extraction and purification Western Blotting Site-directed Mutagenesis Protein Purification Cell Culture Molecular Biology Genetics Protein Expression
Name / Title
Company / Classification
Phones & Addresses
Hui Qing Shao President
KINGART INC
16618 Mosscreek St, Tustin, CA 92782
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