The Brigham and Women's Hospital, Inc. - Boston MA
International Classification:
C12Q 168 G01N 3567 C07H 1204
US Classification:
435 6, 436504, 536 231, 536 241
Abstract:
The present invention is directed to a DNA element that enhances the translation of the human amyloid precursor protein (APP) gene. The enhancer may be incorporated into expression vectors to enhance recombinant protein production. In addition, the invention is directed to an assay that utilizes vectors containing the translation enhancer element for the purpose of identifying agents that modulate the expression of the human amyloid precursor protein. These agents will ultimately be used to suppress APP expression in patients with Alzheimer's disease.
Peptides Derived From The Human Amyloid Precursor Protein
The Brigham and Women's Hospital, Inc. - Boston MA
International Classification:
A61K 38/17 C07K 14/435
US Classification:
514 13, 530326
Abstract:
The present invention is directed to certain peptides that correspond to sequence elements within the human Alzheimer's amyloid precursor protein (APP). These peptides may be used to protect cells from iron catalyzed oxidative damage.
Translation Enhancer Elements Of Genes Encoding Human Tau Protein And Human Alpha-Synuclein Protein
The invention relates to translation enhancer elements that enhance translation of the gene encoding the human microtubule-associated tau protein and nucleic acid molecules that enhance translation of the gene encoding the human α-synuclein protein. The translation enhancer elements of the invention are useful in compositions and methods for identifying compounds for the prevention and/or treatment of neurodegenerative disease. The invention also includes in some aspects, vectors that include a translation enhancer element of the invention. The invention also includes the use of enhancer element containing vectors in methods to produce recombinant protein and in assays to identify compounds that modulate expression of tau protein or α-synuclein protein.
Translation Enhancer Elements Of Genes Encoding Human Tau Protein And Human Alpha-Synuclein Protein
Jack Rogers - Arlington MA, US Avi Friedlich - Charlestown MA, US
International Classification:
C12P 21/02 C07H 21/00 C12N 15/74 C12N 5/10
US Classification:
435 691, 536 231, 4353201, 435325
Abstract:
The invention relates to translation enhancer elements that enhance translation of the gene encoding the human microtubule-associated tau protein and nucleic acid molecules that enhance translation of the gene encoding the human α-synuclein protein. The translation enhancer elements of the invention are useful in compositions and methods for identifying compounds for the prevention and/or treatment of neurodegenerative disease. The invention also includes in some aspects, vectors that include a translation enhancer element of the invention. The invention also includes the use of enhancer element containing vectors in methods to produce recombinant protein and in assays to identify compounds that modulate expression of tau protein or α-synuclein protein.
Translation Enhancer Element Of The Human Amyloid Precursor Protein Gene
The Brigham and Women's Hospital, Inc. - Boston MA
International Classification:
C07H 2104 C12N 1509 C12N 510 C12N 1503
US Classification:
536 241
Abstract:
The present invention is directed to a DNA element that enhances the translation of the human amyloid precursor protein (APP) gene. The enhancer may be incorporated into expression vectors to enhance recombinant protein production. In addition, the invention is directed to an assay that utilizes vectors containing the translation enhancer element for the purpose of identifying agents that modulate the expression of the human amyloid precursor protein. These agents will ultimately be used to suppress APP expression in patients with Alzheimer's disease.
Hussey Corporation Food Production · Sales And Installation Of Spectator Seating · Mfg Public Building Furniture · Institutional Furniture Mfg
38 Dyer St Ext, North Berwick, ME 03906 Dyer St, North Berwick, ME 03906 875 Ave Of The Americas SUITE 501, New York, NY 10001 323 Ctr St STE 1202, Little Rock, AR 72201 2076762271, 2076762222
UBS Jersey City, NJ Apr 2012 to Oct 2012 Equity and Options Trade Support SpecialistUBS Jersey City, NJ Jan 2011 to Oct 2012 Client Services AssociateAIG VALIC Fresno, CA Jan 2009 to Jun 2010 Financial AdvisorWADDELL & REED Fresno, CA Oct 2007 to Jan 2009 Financial Advisor
Education:
BARUCH COLLEGE, ZICKLIN SCHOOL OF BUSINESS New York, NY Sep 2014 Master of Science in Financial Statement Analysis and Securities ValuationCALIFORNIA STATE UNIVERSITY Fresno, CA 2007 Bachelor of Science in Business Administration in Finance
Skills:
Computer: Proficient in MS Office Suite (Excel, Word, PowerPoint, Outlook)
Both of us identified that all the apps out there at the moment are very much casual dating apps which focus on facilitating hookups, co-founder Jack Rogers told The Independent in an interview.
Date: Feb 17, 2018
Category: Sci/Tech
Source: Google
Source Of Fungal Illness Discovered In Eastern Washington Soil
You know, I have been interested in the fungus for years and years, said Washington State University mycologist Jack Rogers. But I only found out last week that actually [we] had the fungus in this state. [It] apparently established here.
Date: May 05, 2014
Category: Health
Source: Google
Some Tea Party activists say supporters would eventually back Mitt Romney
Jack Rogers, a lay Baptist minister in suburb outside Minneapolis and a co-coordinator of the North Metro Tea Party Patriots, had favored Bachmann. In reality, the Tea Party people I know . . . are going to support any candidate who stands against Barack Obama, he said.
Date: Feb 05, 2012
Source: Google
Youtube
Rocket Raceway Helmet Cam - Jack Rogers (Alle...
MXPTV caught the 50cc racing action as Cycle Effex/Limited Decal/Cobra...
Category:
Sports
Uploaded:
20 Sep, 2010
Duration:
4m 55s
Not Fair On Me - Jack Rogers
Jack From Live! From The Crime Scene plays there *NEW* acoustic song. ...
Category:
Music
Uploaded:
18 Apr, 2008
Duration:
2m 28s
Jack Rogers - Rawtenstall Annual Fair
Jack Rogers, aged 7, performing in the Laneshaw Bridge Primary School ...
Category:
Comedy
Uploaded:
13 Jul, 2008
Duration:
2m 36s
Dr. Jack Rogers on the Bible and Homosexuality
First Presbyterian Church in Cedar Rapids hosted author and theologian...
Category:
People & Blogs
Uploaded:
28 Sep, 2007
Duration:
3m 32s
Jack Rogers at Pendle Hippodrome
Jack Rogers, aged 8, performing in the Laneshaw Bridge Primary School ...