Jacob L Gibson

US Patent:

42603935, Apr 7, 1981

Filed:

Jan 15, 1979

Appl. No.:

6/003260

Inventors:

Jacob J. Gibson - Alexandria VA

Assignee:

Technology Resources, Inc. - Washington DC

International Classification:

G01N 3352
G01N 3372

US Classification:

23230B

Abstract:

A diagnostic method and indicator for heme in controlled sensitivity is provided by impregnating a bibulous body, such as a test strip with a solution of a color indicator in leuco form and drying and storing in stable active form, and in use applying to the strip a test sample containing heme. The test color is then developed in the strip by wetting the test sample and strip in contact therewith with a peroxide solution of a solvent for the leuco dye carrying the oxygen released from the peroxide by the heme peroxidase in the test sample, such as blood or body tissue or residues containing occult blood whose presence is to be determined.