James D Ball

US Patent:

20110318820, Dec 29, 2011

Filed:

Jun 29, 2011

Appl. No.:

13/172048

Inventors:

Wolfgang Hinz - Killingworth CT, US
David Light - New Haven CT, US
Todd Rearick - Cheshire CT, US
James Ball - Ledyard CT, US

Assignee:

LIFE TECHNOLOGIES CORPORATION - Carlsbad CA

International Classification:

C12M 1/34

US Classification:

4352872

Abstract:

The disclosure relates to novel particle compositions and methods of making said compositions having applications in nucleic acid analysis, as well as apparatuses and systems for the same.

US Patent:

20220193576, Jun 23, 2022

Filed:

Dec 30, 2021

Appl. No.:

17/566511

Inventors:

- Carlsbad CA, US
James A. Ball - Ledyard CT, US

International Classification:

B01D 17/04
C07H 1/06
C07H 21/00
C12Q 1/6806

Abstract:

A method of recovering a bead support from an emulsion includes supplying an aqueous surfactant solution into a centrifuge tube; supplying a hydrophobic liquid over the surfactant solution in the centrifuge tube, wherein a ratio of the volume of the aqueous surfactant solution to the volume of the hydrophobic liquid is not greater than 0.5; and applying an emulsion over the hydrophobic liquid while centrifuging, the emulsion comprising a dispersed aqueous phase including the bead support, the emulsion breaking and material of the dispersed phase preferentially partitioning to the surfactant solution.

US Patent:

20230037531, Feb 9, 2023

Filed:

Aug 10, 2022

Appl. No.:

17/818869

Inventors:

- Carlsbad CA, US
James A. Ball - Ledyard CT, US
Wolfgang Hinz - Killingworth CT, US
Michael L. Minto - Colechester CT, US
Scott Parker - Madison CT, US
David M. Cox - Foster City CA, US
Alexander Mastroianni - Alameda CA, US
Jeremy Gray - Larkspur CA, US
Marc Glazer - San Jose CA, US
Kimberly Gorrell - Belmont CA, US

International Classification:

C12Q 1/6869
G01N 27/414

Abstract:

A sensor apparatus includes a substrate, a semiconductor device disposed over the substrate, the semiconductor device having a surface electrode structure, and a saccharide coating formed over the surface electrode structure. The saccharide coating can be removed prior to use. The semiconductor device can further include a well and optionally a bead disposed in the well.

US Patent:

20210130891, May 6, 2021

Filed:

Jan 11, 2021

Appl. No.:

17/146376

Inventors:

- Carlsbad CA, US
Todd ROSWECH - Westbrook CT, US
Jon A. HOSHIZAKI - Cupertino CA, US
Albert L. CARRILLO - South San Francisco CA, US
James A. BALL - Ledyard CT, US

International Classification:

C12Q 1/6869
G01N 27/414
C12Q 1/6806
B01F 5/06
B01F 11/00
B01L 3/00
B01F 1/00
G01N 35/10

Abstract:

A method of preparing reagents includes inserting a cartridge into an instrument. The cartridge includes a plurality of reagent enclosures disposed in a cavity of the cartridge and exposing a port to an exterior of the cartridge. Each reagent enclosure includes a reagent container including a reagent and an internal cavity defining a compressible volume, an opening defined through the reagent container to the internal cavity. The method further includes connecting a plurality of fluid ports to the openings of the plurality of reagent enclosures; applying a solution through the fluid ports to at least partially fill the plurality of reagent enclosures; and cycling a pressure of the cavity, whereby for each of the reagent enclosures, during increasing pressure, the solution enters the internal cavity of the reagent container, combines with the reagent, and compresses the compressible volume, and during decreasing pressure, the compressible volume decreases and the reagent is ejected through the opening.

US Patent:

20200282336, Sep 10, 2020

Filed:

Feb 10, 2020

Appl. No.:

16/786913

Inventors:

- Carlsbad CA, US
James A. BALL - Ledyard CT, US

International Classification:

B01D 17/04
C07H 1/06
C07H 21/00
C12Q 1/6806

Abstract:

A method of recovering a bead support from an emulsion includes supplying an aqueous surfactant solution into a centrifuge tube; supplying a hydrophobic liquid over the surfactant solution in the centrifuge tube, wherein a ratio of the volume of the aqueous surfactant solution to the volume of the hydrophobic liquid is not greater than 0.5; and applying an emulsion over the hydrophobic liquid while centrifuging, the emulsion comprising a dispersed aqueous phase including the bead support, the emulsion breaking and material of the dispersed phase preferentially partitioning to the surfactant solution.

US Patent:

20200216893, Jul 9, 2020

Filed:

Mar 20, 2020

Appl. No.:

16/824920

Inventors:

- Carlsbad CA, US
James A. Ball - Ledyard CT, US
Wolfgang Hinz - Killingworth CT, US
Michael L. Minto - Colechester CT, US
Scott Parker - East Haven CT, US
David M. Cox - Foster City CA, US
Alexander Mastroianni - Alameda CA, US
Jeremy Gray - Larkspur CA, US
Marc Glazer - San Jose CA, US
Kimberly Gorrell - Belmont CA, US

International Classification:

C12Q 1/6869
G01N 27/414

Abstract:

A sensor apparatus includes a substrate, a semiconductor device disposed over the substrate, the semiconductor device having a surface electrode structure, and a saccharide coating formed over the surface electrode structure. The saccharide coating can be removed prior to use. The semiconductor device can further include a well and optionally a bead disposed in the well.

US Patent:

20190264274, Aug 29, 2019

Filed:

Feb 28, 2019

Appl. No.:

16/289508

Inventors:

- Carlsbad CA, US
Todd Roswech - Westbrook CT, US
Jon A. Hoshizaki - Cupertino CA, US
Albert L. Carrillo - South San Francisco CA, US
James A, Ball - Ledyard CT, US

International Classification:

C12Q 1/6869
B01F 5/06
B01F 11/00
B01L 3/00
G01N 35/10
C12Q 1/6806
B01F 1/00
G01N 27/414

Abstract:

A method of preparing reagents includes inserting a cartridge into an instrument. The cartridge includes a plurality of reagent enclosures disposed in a cavity of the cartridge and exposing a port to an exterior of the cartridge. Each reagent enclosure includes a reagent container including a reagent and an internal cavity defining a compressible volume, an opening defined through the reagent container to the internal cavity. The method further includes connecting a plurality of fluid ports to the openings of the plurality of reagent enclosures; applying a solution through the fluid ports to at least partially fill the plurality of reagent enclosures; and cycling a pressure of the cavity, whereby for each of the reagent enclosures, during increasing pressure, the solution enters the internal cavity of the reagent container, combines with the reagent, and compresses the compressible volume, and during decreasing pressure, the compressible volume decreases and the reagent is ejected through the opening.

US Patent:

20190071723, Mar 7, 2019

Filed:

Nov 6, 2018

Appl. No.:

16/182384

Inventors:

- Carlsbad CA, US
James A. BALL - Ledyard CT, US
Wolfgang HINZ - Killingworth CT, US
Michael L. MINTO - Colechester CT, US
Scott PARKER - East Haven CT, US
David M. COX - Foster City CA, US
Alexander MASTROIANNI - Alameda CA, US
Jeremy GRAY - Larkspur CA, US
Marc GLAZER - San Jose CA, US
Kimberly GORRELL - Belmont CA, US

International Classification:

C12Q 1/6869
G01N 27/414

Abstract:

A sensor apparatus includes a substrate, a semiconductor device disposed over the substrate, the semiconductor device having a surface electrode structure, and a saccharide coating formed over the surface electrode structure. The saccharide coating can be removed prior to use. The semiconductor device can further include a well and optionally a bead disposed in the well.

Address:

2208 Steele St, Longmont, CO 80501

VIN:

1GTEK19Z17Z195846

Make:

GMC

Model:

SIERRA 1500 CLASSIC

Year:

2007