A composition and method for the treatment of drug abuse which comprises the administration by means of inhalation of an effective amount of a therapeutic smoke from a composition derived from a mixture of natural ingredients, primarily from grain products. The smoke from a composition consisting of whole ground rye, cornstarch, corn silk, and red clover can be breathed in from the surrounding atmosphere of an enclosed environment. A milder composition consisting of whole ground rye, cornstarch, corn silk, red clover, and wheat bran in unit form is particularly suitable for administration by smoking. The compositions produce a therapeutic smoke upon burning which when inhaled or smoked are effective for the treatment of cocaine habituation by blocking the reinforcing properties of the drug and for alleviating the unpleasant symptoms accompanying withdrawal from cocaine dependency.