James T Forbes

US Patent:

6365551, Apr 2, 2002

Filed:

May 30, 2000

Appl. No.:

09/583809

Inventors:

Daniel R. Wright - St. Louis MO
James C. Forbes - Glenview IL
Paul D. Berger - Sugarland TX
Antonio M. Jimenez - Missouri TX

Assignee:

Monsanto Technology LLC - St. Louis MO

International Classification:

A01N 5702

US Classification:

504206

Abstract:

There are provided compositions of certain polyoxyalkylene alkylamine surfactants having eye irritation reduced by the addition of an effective amount of a sulfated polyoxyalkylene alkylphenol, alcohol sulfate, polyoxyalkylene alcohol sulfate, mono- or dialcohol phosphate, mono- or di-(polyoxyalkylene alcohol) phosphate, polyoxyalkylene alkylphenol carboxylate or polyoxyalkylene alcohol carboxylate surfactant. Also provided are pesticidal, particularly herbicidal, compositions comprising polyoxyalkylene alkylamine surfactants having eye irritation reduced by addition of these eye irritation reducing compounds.

US Patent:

6579895, Jun 17, 2003

Filed:

May 25, 2001

Appl. No.:

09/866165

Inventors:

Aziz Karim - Skokie IL
Andrew M. Brugger - Libertyville IL
Ping Gao - Portage MI
Fred Hassan - Peapack NJ
James C. Forbes - Glenview IL

Assignee:

Pharmacia Corporation - St. Louis MO

International Classification:

A61K 31415

US Classification:

514406, 514263, 514282, 514317

Abstract:

There is provided a method of rapidly relieving pain in a mammalian, preferably human, subject. The method comprises orally administering to the subject an effective pain-relieving amount of a composition comprising celecoxib formulated in such a way as to provide, when tested in fasting humans in accordance with standard pharmacokinetic practice, a blood plasma concentration profile of celecoxib in which a concentration of about 250 ng/ml is attained not later than about 30 minutes after oral administration.

US Patent:

6626678, Sep 30, 2003

Filed:

Apr 24, 2001

Appl. No.:

09/841377

Inventors:

Elinor Isobel Forbes - Glenview IL 60025
James Carnegie Forbes - Glenview IL 60025

International Classification:

G09B 1900

US Classification:

434247, 434259, 434258, 434236, 446 1, 273153 R, 273156

Abstract:

A new method is described of providing mental stimulus to a subject suffering significant cognitive and/or sensory impairment or deterioration, for example a subject having a medically diagnosed dementia such as Alzheimers disease, and thereby enhancing the subjects psychological condition. The method of the invention comprises causing the subject to handle an article comprising a plurality of pieces that (a) individually have a surface layer formed of a soft fabric, and (b) collectively exhibit differing tactility when handled by the subject.

US Patent:

20020107250, Aug 8, 2002

Filed:

Apr 17, 2001

Appl. No.:

09/836905

Inventors:

Madhusudan Hariharan - Evanston IL, US
Tugrul Kararli - Skokie IL, US
Fred Hassan - Peapack NJ, US
James Forbes - Glenview IL, US

International Classification:

A61K031/50
A61K031/415
A61K031/353
A61K031/122

US Classification:

514/247000, 514/406000, 514/456000, 514/690000

Abstract:

An orally deliverable pharmaceutical composition is provided comprising a selective cyclooxygenase-2 inhibitory drug of low water solubility, for example celecoxib, and a glycol ether, for example diethylene glycol monoethyl ether. At least a substantial part of the drug is in dissolved or solubilized form in a solvent liquid comprising the glycol ether. The composition has rapid-onset properties and is useful in treatment of cyclooxygenase-2 mediated conditions and disorders, particularly pain. For relief of pain in headache or migraine, the composition can optionally be administered together with a vasodilator.

US Patent:

20020122860, Sep 5, 2002

Filed:

May 2, 2002

Appl. No.:

10/136378

Inventors:

Richard Wildasin - Lockport IL, US
James Forbes - Lockport IL, US
Raymond Robey - Naperville IL, US
Armand Paradis - Naperville IL, US

International Classification:

A23L003/16

US Classification:

426/521000

Abstract:

A continuous method using gaseous carbon dioxide or a pressurized flow of liquefied carbon dioxide is described to reduce microbial and/or enzymatic activity in a liquid product. The carbon dioxide is combined with a pressurized flow of the liquid product, or the mixture is pressurized after the mixture is formed. The pressure and temperature in the flow regions are maintained at a level which is sufficient to keep the carbon dioxide in a continuous liquid state, but which does not freeze the liquid product. The pressurized mixture of the carbon dioxide and liquid product flows through a reaction zone for a sufficient time to reduce harmful microorganisms and/or inactivate enzymes and then enters one or more expansion stages wherein the pressure of the mixture flow is sufficiently decreased to vaporize the carbon dioxide for separation from the liquid product. If necessary, heat is applied in at least one of the expansion stages to prevent a freezing of the mixture.

US Patent:

20020142045, Oct 3, 2002

Filed:

Apr 1, 2002

Appl. No.:

10/113157

Inventors:

Tugrul Kararli - Skokie IL, US
Mark Kontny - Libertyville IL, US
Subhash Desai - Wilmette IL, US
Michael Hageman - Portage MI, US
Royal Haskell - Kalamazoo MI, US
Fred Hassan - Peapack NJ, US
James Forbes - Glenview IL, US

International Classification:

A61K031/522
A61K009/14

US Classification:

424/489000, 514/263310, 514/263320

Abstract:

Pharmaceutical compositions are provided comprising one or more orally deliverable dose units, each comprising a selective cyclooxygenase-2 inhibitory drug of low water solubility in a therapeutically effective amount, wherein the drug is present in the form of solid particles, about 25% to 100% by weight of which are smaller than 1 m. The compositions are useful in treatment or prophylaxis of cyclooxygenase-2 mediated conditions and disorders and have particular advantages where rapid onset of therapeutic effect is desired.

US Patent:

20030064098, Apr 3, 2003

Filed:

Jun 5, 2001

Appl. No.:

09/874504

Inventors:

Tugrul Kararli - Skokie IL, US
Mark Kontny - Libertyville IL, US
Subhash Desai - Wilmette IL, US
Michael Hageman - Portage MI, US
Royal Haskell - Kalamazoo MI, US
Fred Hassan - Peapack NJ, US
James Forbes - Glenview IL, US

International Classification:

A61K031/522
A61K009/20

US Classification:

424/465000, 514/263340

Abstract:

Pharmaceutical compositions are provided comprising one or more orally deliverable dose units, each comprising a selective cyclooxygenase-2 inhibitory drug of low water solubility in a therapeutically effective amount, wherein the drug is present in the form of solid particles, about 25% to 100% by weight of which are smaller than 1 m. The compositions are useful in treatment or prophylaxis of cyclooxygenase-2 mediated conditions and disorders and have particular advantages where rapid onset of therapeutic effect is desired.

US Patent:

20030134887, Jul 17, 2003

Filed:

Dec 27, 2002

Appl. No.:

10/330946

Inventors:

Aziz Karim - Skokie IL, US
Andrew Brugger - Libertyville IL, US
Ping Gao - Portage MI, US
Fred Hassan - Peapack NJ, US
James Forbes - Glenview IL, US

International Classification:

A61K031/415

US Classification:

514/406000

Abstract:

There is provided a method of rapidly relieving pain in a mammalian, preferably human, subject. The method comprises orally administering to the subject an effective pain-relieving amount of a composition comprising celecoxib formulated in such a way as to provide, when tested in fasting humans in accordance with standard pharmacokinetic practice, a blood plasma concentration profile of celecoxib in which a concentration of about 250 ng/ml is attained not later than about 30 minutes after oral administration.