James Fort (Irish: Dn R Shamuis) is located on Castlepark peninsula in Kinsale harbour, downstream on the River Bandon from Kinsale and overlooking the ...
James J. Fort - Midlothian VA, US Steven L. Krill - Chatham NJ, US Devalina Law - Libertyville IL, US Yihong Qiu - Gurnee IL, US William R. Porter - Vernon Hills IL, US Eric A. Schmitt - Libertyville IL, US
A pharmaceutical composition is disclosed which comprises a solid dispersion of an HIV protease inhibitor in a water soluble carrier, such as PEG, having enhanced bioavailability and improved dissolution properties. The solid dispersion may optionally be encapsulated in hard gelatin capsules, compressed into a tablet, or may be granulated with a pharmaceutically acceptable granulating agent. Also disclosed are methods of making said solid dispersion and methods of treating an HIV infection employing said solid dispersion.
Graham D. Cook - Midlothian VA, US Todd S. Koch - Powhatan VA, US David H. Giamalva - Gleen Allen VA, US Justin Bianco - Vineland VA, US James J. Fort - Midlothian VA, US Geraldine Doyle - Chatham NJ, US Steven Cooper - Denville NJ, US
Assignee:
Wyeth LLC - Madison NJ
International Classification:
A61K 31/192 A61K 9/00 A61K 31/36 A61K 31/19
US Classification:
514464, 514557, 514570, 424400
Abstract:
The present invention provides a new composition for treating pain-associated sleep disturbances, especially shortened sleep duration, comprising ibuprofen and diphenhydramine. The composition is further prepared as a bilayer tablet or caplet, or alternatively as a soft gelatin capsule composition, to prevent interaction between the active ingredients.
Graham Cook - Midlothian VA, US Todd Koch - Powhatan VA, US David Giamalva - Glen Allen VA, US Justin Bianco - Vineland NJ, US James Fort - Midlothian VA, US Geraldine Doyle - Chatham NJ, US Steven Cooper - Denville NJ, US
International Classification:
A61K031/19 A61K031/135
US Classification:
514/570000, 514/658000
Abstract:
The present invention provides a new composition for treating pain-associated sleep disturbances, especially shortened sleep duration, comprising ibuprofen and diphenhydramine. The composition is further prepared as a bilayer tablet or caplet, or alternatively as a soft gelatin capsule composition, to prevent interaction between the active ingredients.
Inhibitors Of Crystallization In A Solid Dispersion
James Fort - Midlothian VA, US Steven Krill - Gurnee IL, US Devalina Law - Libertyville IL, US Yihong Qiu - Gurnee IL, US Eric Schmitt - Libertyville IL, US
International Classification:
A61K 31/426
US Classification:
514365000
Abstract:
A pharmaceutical composition is disclosed which comprises a solid dispersion of a pharmaceutical compound in a water soluble carrier, such as polyethylene glycol (PEG), and a crystallization inhibitor, such as polyvinylpyrrolidone or hydroxypropylmethylcellulose. The solid dispersion may optionally be encapsulated in hard gelatin capsules, compressed into a tablet, or may be granulated with a pharmaceutically acceptable granulating agent. Also disclosed are methods of making said solid dispersion and methods of treatment employing said solid dispersion.
Graham D. Cook - Midlothian VA, US Todd S. Koch - Powhatan VA, US Justin Bianco - Vineland NJ, US James J. Fort - Midlothian VA, US Geraldine Doyle - Chatham NJ, US Steven Cooper - Denville NJ, US
The present invention provides a new composition for treating pain-associated sleep disturbances, especially shortened sleep duration, comprising ibuprofen and diphenhydramine. The composition is further prepared as a bilayer tablet or caplet, or alternatively as a soft gelatin capsule composition, to prevent interaction between the active ingredients.