James E Freeman

US Patent:

20130059825, Mar 7, 2013

Filed:

Apr 27, 2012

Appl. No.:

13/458847

Inventors:

Niver Panosian Sahakian - Encino CA, US
Bruce A. Campbell - Calabasas CA, US
Spencer Hsiang-Hsi Lin - Yorktown Heights NY, US
James Vincent Freeman - Sandy Hook CT, US
Qimu Liao - Alhambra CA, US
Ramon A. Evangelista - Laguna Hills CA, US

Assignee:

Siemens Healthcare Diagnostics Inc. - Tarrytown NY

International Classification:

C07K 16/44
C07H 21/04
G01N 33/566
C12N 15/06
C12P 21/08
G01N 21/76
G01N 33/53
C12N 5/18
A61K 31/59

US Classification:

514167, 5303889, 5303873, 5303898, 435345, 536 2353, 436501, 435 696, 435 792, 435 71, 435452

Abstract:

Provided herein are antigenic molecules that can be used to generate antibodies capable of binding to a vitamin D derivative, such as 25-hydroxyvitamin D2 and/or 25-hydroxyvitamin D3, or a 25-hydroxyvitamin D analog, such as a vitamin D-C22 immunogenic molecule or compound. Antibodies produced using these antigenic molecules, and related antigenic compounds, are also described. In addition, disclosed herein are methods for detecting vitamin D deficiency in a subject, methods for treating a subject suspected of having a vitamin D deficiency, methods for monitoring progression of vitamin D deficiency in a subject, and methods for monitoring treatment of vitamin D deficiency in a subject in need thereof. Also provided are methods and reagents for the detection or quantification of 25-hydroxyvitamin D2 and D3, methods for stabilizing vitamin D analogs, and methods for separating 25-hydroxyvitamin D2 and D3 from vitamin D binding protein in a biological sample.

US Patent:

41956729, Apr 1, 1980

Filed:

May 24, 1978

Appl. No.:

5/909037

Inventors:

James F. Freeman - Long Beach CA

International Classification:

B65B 3100

US Classification:

141 91

Abstract:

A portable liquid pesticide transfer assembly capable of being removably mounted on a side wall that extends upwardly from a bed portion of a conventional pickup truck. The assembly when so mounted permits liquid pesticide to be transferred through a closed system from the container in which it is marketed to a tank for dispensing purposes without danger of the pesticide contacting the user or the user being subjected to the fumes thereof. The container after the pesticide is removed therefrom is capable of being washed together with the assembly, without the user being subjected to inadvertent contact with the pesticide containing wash water. The assembly includes a closure for removably sealing the container when the container has a quantity of pesticide remaining therein.

US Patent:

40349438, Jul 12, 1977

Filed:

Jul 19, 1976

Appl. No.:

5/706807

Inventors:

James F. Freeman - Long Beach CA

International Classification:

B43L 700
B31L 700

US Classification:

248 1

Abstract:

An assembly capable of removably engaging a first leg of a welder's square, and supporting the welder's square on a substantially horizontal pipe or structural member, with the second leg of the welder's square normally disposed to the longitudinal center line of the pipe or structural member. When the welder's square and assembly are so mounted as a unit on the pipe, the second leg may be used to align a flange relative to an end of the pipe, determine whether an end edge of the pipe is normal to the longitudinal center line of the pipe, and indicate a transverse cutting line on the pipe. Two of the units when disposed back-to-back may be used to longitudinally align two lengths of pipe that have adjacent ends thereof in abutting contact. The assembly may be used to support a welder's square on a substantially horizontal structural member, such as a channel or eye beam, to achieve like results.