Val S. Goodfellow - Westminster CO Donald A. McLeod - Westminster CO James Ivan Gerrity - Arvada CO Christopher P. Laudeman - Aurora CO Michael R. Burkard - Broomfield CO
Assignee:
Cortech, Inc. - Denver CO
International Classification:
G01N 3353 G01N 33566 G01N 33543
US Classification:
435 71
Abstract:
The invention provides a method of synthesizing N-substituted 1,4-piperazines and N-substituted 1,4-piperazinediones. The invention also provides a method for synthesing combinatorial libraries of piperazine derivatives which can be assayed for biological activity in pre-specified ligand binding or enzymatic activity screens.