Thermo Fisher Scientific
Senior Manager, Project Management
Thermo Fisher Scientific
Manager, Project Management
Patheon
Manager of Applied Technologies
Agere Pharmaceuticals, Inc. Jul 2014 - Mar 2015
Manager of Applied Technologies
Arrowhead Pharmaceuticals, Inc. Nov 2010 - Feb 2014
Director, Research and Development
Education:
Northwestern University 1999 - 2004
Doctorates, Doctor of Philosophy, Materials Science, Engineering
Cornell University 1995 - 1999
Bachelors, Bachelor of Science, Materials Science, Engineering
Skills:
Nanotechnology Chemistry Biotechnology R&D Materials Science Spectroscopy Technology Transfer Biomaterials Nanomaterials Scanning Electron Microscopy Hplc Powder X Ray Diffraction Uv/Vis Microscopy Tem Thin Films Tissue Engineering Optical Microscopy Xps Surface Chemistry Polymer Characterization Organic Chemistry Electron Microscopy Biomedical Engineering Mass Spectrometry Afm Fluorescence Electrochemistry Polymers Nanofabrication Pre Clinical Studies Experimental Design Analytical Chemistry Drug Delivery Spray Drying Amorphous Drug Dispersions Entrepreneurship Grant Writing Technical Writing Drug Development Glp Fda Gmp Liquid Crystals Polarized Light Microscopy Peptides Solid Phase Synthesis Nmr Toxicology Intellectual Property Ftir
Us Patents
Oligo(P-Phenylene Vinylene) Amphiphiles And Methods For Self-Assembly
Samuel I. Stupp - Chicago IL, US Kanya Rajangam - Wilmette IL, US James F. Hulvat - Chicago IL, US
Assignee:
Northwestern University - Evanston IL
International Classification:
A61K 38/10
US Classification:
514 14, 530326
Abstract:
Peptide amphiphiles and related compositions comprising sulfated polysaccharides, such as but not limited to sulfated glycosaminoglycans, and methods of use relating to the encapsulation and/or controlled release of angiogenic growth factor(s).
Peptide Amphiphiles Having Improved Solubility And Methods Of Using Same
Disclosed herein are novel peptide amphiphile molecules and compositions discovered to possess improved solubility in aqueous buffers which, in turn, facilitates purification required for pharmaceutical applications, particularly for in vivo administration to human patients. In addition, gels of such peptide amphiphile compositions are shown herein to possess unexpectedly superior gelation kinetics and rheological properties, including an increased mechanical stiffness, which better mimics the mechanical properties of natural central nervous system tissues.
Samuel Stupp - Chicago IL, US James Hulvat - Chicago IL, US
International Classification:
H01L021/302
US Classification:
438/745000
Abstract:
A method of preparing a conductive polymeric film, includes providing a liquid crystal phase comprising a plurality of hydrophobic cores, the phase on a substrate, introducing a hydrophobic component to the phase, the component a conductive polymer precursor, and applying an electric potential across the liquid crystal phase, the potential sufficient to polymerize the said precursor.
The application provides synthetic peptide conjugates capable of targeting and causing ablation of adipose tissue in mammal comprising at least one targeting peptide and at least one therapeutic peptide. The synthetic peptide conjugates are envisaged to have decreased physiological toxicity and/or enhanced in situ cytotoxicity compared to the peptide CKGGRAKDC-GG-(KLAKLAKKLAKLAK) (SEQ ID NO: 2).
Pharmaceutical Compositions For The Treatment Of Hbv
- San Francisco CA, US George Koan WONG - Belle Mead NJ, US Kirk HENNE - Belmont CA, US James Francis HULVAT - Cincinnati OH, US Sanjay KONAGURTHU - Bend OR, US Ian Scott MCINTOSH - Bend OR, US Matthew David WESSEL - Sisters OR, US Thomas REYNOLDS - Bend OR, US Richard J. COLONNO - San Francisco CA, US Uri A. LOPATIN - San Francisco CA, US
The present disclosure provides, in part, pharmaceutical compositions that comprise a spray dried dispersion which contains the disclosed compound, and optionally, pharmaceutical excipients. The pharmaceutical compositions of the disclosure may be used in the treatment of Hepatitis B (HBV).
Novel Formulations Of A Bruton's Tyrosine Kinase Inhibitor
- Sunnyvale CA, US Ching Wah Chong - Fremont CA, US Robert Kuehl - San Francisco CA, US Cassandra Shu - Belmont CA, US Pearl Shwe-Cho Tay - Union City CA, US James Francis Hulvat - Bend OR, US Alexander Jacob McVey - Bend OR, US Ryan Mitchell Minikis - Bend OR, US
Described herein is the Bruton's tyrosine kinase (Btk) inhibitor 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one, including novel pharmaceutical formulations thereof. Also disclosed are pharmaceutical compositions that include the Btk inhibitor, as well as methods of using the Btk inhibitor, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.
Novel Formulations Of A Bruton's Tyrosine Kinase Inhibitor
- Sunnyvale CA, US Ching Wah Chong - Fremont CA, US Robert Kuehl - San Francisco CA, US Cassandra Shu - Belmont CA, US Pearl Shwe-Cho Tay - Union City CA, US James Francis Hulvat - Bend OR, US Alexander Jacob McVey - Bend OR, US Ryan Mitchell Minikis - Bend OR, US
Described herein is the Bruton's tyrosine kinase (Btk) inhibitor 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one, including novel pharmaceutical formulations thereof. Also disclosed are pharmaceutical compositions that include the Btk inhibitor, as well as methods of using the Btk inhibitor, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.
James Hulvat, head of research and development for Ablaris Therapeutics, said the decision to test the agent first in obese prostate-cancer patients reflected in part the interests M.D. Anderson, which is paying for the initial study, and the agent's potential for demonstrating an important benefit