James Matthew Jacobs

US Patent:

20030061348, Mar 27, 2003

Filed:

Sep 24, 2001

Appl. No.:

09/960320

Inventors:

James Jacobs - Suwanee GA, US

International Classification:

G06F015/173
G06F015/16

US Classification:

709/225000, 709/203000

Abstract:

A system for providing specific information to a user includes a subscription server. The subscription server collects metric information from a plurality of metric publication providers. A user may log into the subscription server and subscribe to receive a specific set of metric data from a variety of the metric publication providers. The user may define a user's view that presents only the metric data selected. A publication provider wishing to provide metric data via the subscription service send a message to the subscription server indicating which metric information it publishes. The publication provider provides the metric information in a standardized form to the subscription server. The publication provider may include an adapter that puts the metric information into standardized form.

US Patent:

50104730, Apr 23, 1991

Filed:

Aug 31, 1989

Appl. No.:

7/401996

Inventors:

James R. Jacobs - Durham NC

Assignee:

Duke University - Durham NC

International Classification:

G05B 1304
A61M 5172

US Classification:

364150

Abstract:

A method and apparatus for controlling a model based open-loop process and more specifically, the concentration of a drug delivered intravenously to a patient as a function of the rate of infusion. A three-compartment pharmacokinetic model is preferably used to determine the plasma drug concentrations corresponding to two arbitrarily selected rates of infusion. Based upon the linear relationship between corresponding data pairs, each pair comprising a rate of infusion and a corresponding plasma drug concentration, an interpolated rate is determined by a microprocessor (100) as a function of a specified plasma drug concentration, in accordance with program steps stored in a read only memory (ROM) 104. The actual infusion rate of the drug during successive time intervals is repetitively used to compute the plasma drug concentration at the end of each time interval. In each successive iteration, state variables from the previous computation of the plasma drug concentration are used to determine the next interpolated infusion rate.