James Landro - Cheshire CT, US David Osterman - Glastonbury CT, US Walter Pickett - Madison CT, US
Assignee:
Bayer Pharmaceuticals Corporation - West Haven CT
International Classification:
C12Q001/48
US Classification:
435015000
Abstract:
The present invention relates to methods for assessing enzyme activity utilizing a phase partition system. In addition, the present invention also relates to methods for screening and identifying compounds that may be used, for example, for the treatment of diabetes, diabetes-related disorders, obesity, cardiovascular disease, cancer, and other diseases or disorders, using this phase partition system.
James Landro - Cheshire CT, US David Osterman - Glastonbury CT, US Walter Pickett - Madison CT, US
Assignee:
Bayer Pharmaceuticals Corporation - West Haven CT
International Classification:
C12Q 1/48
US Classification:
435015000
Abstract:
The present invention relates to methods for assessing enzyme activity utilizing a phase partition system. In addition, the present invention also relates to methods for screening and identifying compounds that may be used, for example, for the treatment of diabetes, diabetes-related disorders, obesity, cardiovascular disease, cancer, and other diseases or disorders, using this phase partition system.
- Nijmegen, NL Hans de Haard - Oudelande, NL James A. Landro - Cheshire CT, US
International Classification:
C07K 16/18 A61P 3/06 A61P 9/10 A61K 31/397
Abstract:
The instant disclosure provides antibodies that specifically bind to ApoC3 (e.g., human ApoC3) and antagonize ApoC3 function. Also provided are pharmaceutical compositions comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies.