James B Little

US Patent:

6349170, Feb 19, 2002

Filed:

Jan 11, 2000

Appl. No.:

09/481454

Inventors:

Jean-Louis Fressinet - St. Jean de Touslas, FR
Alain Frugier - Tignieu, FR
David B. Greene - Lakewood CO
James Little - Bailey CO

Assignee:

Gambro Inc. - Lakewood CO

International Classification:

A61F 700

US Classification:

392470, 210232, 604 504

Abstract:

An integrated CRRT method and apparatus incorporates steps and means for compensating for heat loss from blood in an extracorporeal circuit. A blood warmer is designed to engage and hold a disposable blood tube segment to transfer heat at a closely controlled temperature to blood flowing in the disposable blood tube segment. Another significant aspect of the present invention is a blood tube segment for engagement with the blood warmer is located in downstream of a dialyzer and upstream of a venous pressure monitor, an air bubble detector and a venous line clamp. The disposable blood tube segment may be selectively connected when heat loss compensation is required and left disconnected when heat loss compensation is not required.

US Patent:

6629946, Oct 7, 2003

Filed:

Jan 16, 2002

Appl. No.:

10/051431

Inventors:

Jean-Louis Fressinet - F69700 St. Jean de Touslas, FR
Alain Frugier - F-38230 Tignieu, FR
David B. Greene - Lakewood CO 80228
James Little - Bailey CO 80421

International Classification:

A61M 3700

US Classification:

604 501, 392470, 604 613

Abstract:

An integrated CRRT method and apparatus incorporates steps and means for compensating for heat loss from blood in an extracorporeal circuit. A blood warmer is designed to engage and hold a disposable blood tube segment to transfer heat at a closely controlled temperature to blood flowing in the disposable blood tube segment. Another significant aspect of the present invention is a blood tube segment for engagement with the blood warmer is located in downstream of a dialyzer and upstream of a venous pressure monitor, an air bubble detector and a venous line clamp. The disposable blood tube segment may be selectively connected when heat loss compensation is required and left disconnected when heat loss compensation is not required.

US Patent:

51078546, Apr 28, 1992

Filed:

Oct 17, 1990

Appl. No.:

7/600003

Inventors:

Sarah A. Knotts - Boulder CO
James D. Little - Longmont CO
Brett R. Skelton - Louisville CO

Assignee:

Boulder Impact Monitors, Inc. - Boulder CO

International Classification:

A61B 5103

US Classification:

128779

Abstract:

An orthopedic exercise chamber such as a slipper including a light-weight, self-contained limb load monitor is disclosed. The limb load sensor circuit provides extended service life for the miniature power supply that is included in the slipper, thereby making the slipper suitable for out-patient use. A fluid-filled plantar chamber that supports the entire load borne by the patient's foot is connected to the sensor circuit, thereby providing improved monitoring of the load being carried by the leg or foot that must be protected from excessive loading.

US Patent:

20190366089, Dec 5, 2019

Filed:

Jul 18, 2019

Appl. No.:

16/516031

Inventors:

- Sylmar CA, US
Kelly Hobart McClure - Simi Valley CA, US
James S. Little - Arvada CO, US
Rongqing Dai - Valencia CA, US
Arup Roy - Los Angeles CA, US
Richard Agustin Castro - Santa Monica CA, US
John Reinhold - Tarzana CA, US
Kea-Tiong Tang - Hsinchu, TW
Sumit Yadav - Lake Forest CA, US
Chunhong Zhou - San Diego CA, US
David Daomin Zhou - Valencia CA, US
Pishoy Maksy - Newport Beach CA, US

Assignee:

Second Sight Medical Products, Inc. - Sylmar CA

International Classification:

A61N 1/36
A61N 1/05

Abstract:

In electrically stimulating neural tissue it is important to prevent over stimulation and unbalanced stimulation, which would cause damage to the neural tissue, the electrode, or both. It is critical that neural tissue is not subjected to any direct current or alternating current above a safe threshold. Further, it is important to identify defective electrodes, as continued use may result in neural damage and further electrode damage. The present invention presents system and stimulator control mechanisms to prevent damage to neural tissue.

US Patent:

20190366091, Dec 5, 2019

Filed:

Jul 18, 2019

Appl. No.:

16/516058

Inventors:

- Sylmar CA, US
Kelly Hobart McClure - Simi Valley CA, US
James S. Little - Arvada CO, US
Rongqing Dai - Valencia CA, US
Arup Roy - Los Angeles CA, US
Richard Agustin Castro - Santa Monica CA, US
John Reinhold - Tarzana CA, US
Kea-Tiong Tang - Hsinchu, TW
Sumit Yadav - Lake Forest CA, US
Chunhong Zhou - San Diego CA, US
David Daomin Zhou - Valencia CA, US
Pishoy Maksy - Newport Beach CA, US

Assignee:

Second Sight Medical Products, Inc. - Sylmar CA

International Classification:

A61N 1/36
A61N 1/05

Abstract:

In electrically stimulating neural tissue it is important to prevent over stimulation and unbalanced stimulation, which would cause damage to the neural tissue, the electrode, or both. It is critical that neural tissue is not subjected to any direct current or alternating current above a safe threshold. Further, it is important to identify defective electrodes, as continued use may result in neural damage and further electrode damage. The present invention presents system and stimulator control mechanisms to prevent damage to neural tissue.

US Patent:

20190336769, Nov 7, 2019

Filed:

Jul 18, 2019

Appl. No.:

16/516078

Inventors:

- Sylmar CA, US
Kelly Hobart McClure - Simi Valley CA, US
James S. Little - Arvada CO, US
Rongqing Dai - Valencia CA, US
Arup Roy - Los Angeles CA, US
Richard Agustin Castro - Santa Monica CA, US
John Reinhold - Tarzana CA, US
Kea-Tieng Tang - Hsinchu, TW
Sumit Yadav - Lake Forest CA, US
Chunhong Zhou - San Diego CA, US
David Daomin Zhou - Valencia CA, US
Pishoy Maksy - Newport Beach CA, US

Assignee:

Second Sight Medical Products, Inc. - Sylmar CA

International Classification:

A61N 1/36
A61N 1/05

Abstract:

In electrically stimulating neural tissue it is important to prevent over stimulation and unbalanced stimulation, which would cause damage to the neural tissue, the electrode, or both. It is critical that neural tissue is not subjected to any direct current or alternating current above a safe threshold. Further, it is important to identify defective electrodes, as continued use may result in neural damage and further electrode damage. The present invention presents system and stimulator control mechanisms to prevent damage to neural tissue.

US Patent:

20180178002, Jun 28, 2018

Filed:

Nov 27, 2017

Appl. No.:

15/823459

Inventors:

- Sylmar CA, US
Eugene de Juan - San Francisco CA, US
Mark S Humayun - Glendale CA, US
Kelly McClure - Simi Valley CA, US
Neil Hamilton Talbot - La Crescenta CA, US
Jordan Matthew Neysmith - Mountain View CA, US
Brian V Mech - Santa Clarita CA, US
James Singleton Little - Arvada CO, US
Mohamed Khaldi - Los Angeles CA, US

Assignee:

Second Sight Medical Products, Inc. - Sylmar CA

International Classification:

A61N 1/05
H05K 1/11
H05K 1/03

Abstract:

The disclosure relates to a flexible circuit electrode array comprising: a polymer base layer; metal traces deposited on said polymer base layer, including electrodes suitable to stimulate neural tissue; a polymer top layer deposited on said polymer base layer and said metal traces; and at least one support embedded in said array. The disclosure further relates to a flexible circuit electrode array comprising: a polymer base layer; metal traces deposited on said polymer base layer, including electrodes suitable to stimulate neural tissue; a polymer top layer deposited on said polymer base layer and said metal traces; and a folded flexible circuit cable connecting the electrode array with an interconnection pad. The disclosure further relates to a method of making a flexible circuit electrode array comprising: depositing a polymer base layer; depositing metal on said polymer base layer; patterning said metal to form metal traces; depositing a polymer top layer on said polymer base layer and said metal traces; heating said flexible circuit electrode array in a mold to form a three dimensional shape in said flexible circuit electrode array, embedding a support at least in the base layer, top layer or between the base and top layer, and/or folding a flexible circuit cable at least once connecting the electrode array with an interconnection pad on the array.

US Patent:

20180169413, Jun 21, 2018

Filed:

Feb 1, 2018

Appl. No.:

15/886522

Inventors:

- Sylmar CA, US
Kelly Hobart McClure - Simi Valley CA, US
James S. Little - Arvada CO, US
Rongqing Dal - Valencia CA, US
Arup Roy - Valencia CA, US
Richard Augustin Castro - Sanita Monica CA, US
John Reinhold - Tarzana CA, US
Kea-Tiong Tang - Hsinchu, TW
Sumit Yadav - Lake Forest CA, US
Chunhong Zhou - Encinitas CA, US
David Daomin Zhou - Valencia CA, US
Pishoy Maksy - Newport Beach CA, US

Assignee:

Second Sight Medical Products, Inc. - Sylmar CA

International Classification:

A61N 1/36
A61N 1/05
A61N 1/08

Abstract:

In electrically stimulating neural tissue it is important to prevent over stimulation and unbalanced stimulation which would cause damage to the neural tissue, the electrode, or both. It is critical that neural tissue is not subjected to any direct current or alternating current above a safe threshold. Further, it is important to identify defective electrodes as continued use may result in neural damage and further electrode damage. The present invention presents system and stimulator control mechanisms to prevent damage to neural tissue.