James Reese Matson

US Patent:

6730266, May 4, 2004

Filed:

Jul 25, 2001

Appl. No.:

09/912904

Inventors:

James R. Matson - Dallas TX
Patrice A. Lee - Erie CO

Assignee:

Immunocept, L.L.C. - Dallas TX

International Classification:

A61M 136

US Classification:

422 44, 604 401, 604 501, 604 504, 604 609, 604 611, 210650, 2101952, 210260, 210790

Abstract:

A hemofiltration system for a mammal is provided with a hemofilter and an adsorbent device. The hemofilter removes ultrafiltrate from a blood stream extracted from the mammal to create a filtered blood stream and an ultrafiltrate stream. The adsorbent device has one or more adsorbent materials and is used to adsorb inflammatory mediators from the ultrafiltrate stream received from the hemofilter removing inflammatory mediators that cause inflammatory mediator related disease, sepsis, and SIRS/MODS/MOSF to create a post adsorption ultrafiltrate stream. The post adsorption ultrafiltrate stream is selectively combined with the filtered blood stream and together with the filtered blood stream is returned to the mammal.

US Patent:

6736972, May 18, 2004

Filed:

Mar 23, 2001

Appl. No.:

09/815675

Inventors:

James R. Matson - Dallas TX

Assignee:

Immunocept, L.L.C. - Dallas TX

International Classification:

B01D 6100

US Classification:

210650, 2103216, 210651, 422 44, 514 1, 514 2, 604 401, 604 501, 604 504

Abstract:

The present invention relates to a method and system for providing hemofiltration for reducing inflammatory mediator related diseases. In one form, a hemofiltration system for treating inflammatory mediator related diseases is disclosed. The system includes a hemofilter to receive blood from a specimen, the hemofilter removing selective inflammatory mediators from the blood and at least one therapeutic agent used in association with the hemofilter, the therapeutic agent to reduce adverse inflammatory mediator effects.

US Patent:

6787040, Sep 7, 2004

Filed:

May 15, 2001

Appl. No.:

09/858210

Inventors:

David Radunsky - Dallas TX
James R. Matson - Dallas TX
Patrice A. Lee - Erie CO

Assignee:

Immunocept, L.L.C. - Dallas TX

International Classification:

A61M 134

US Classification:

210651, 210650, 435 2, 604 401, 604 501, 604 504

Abstract:

The present invention relates to a method and system for using a hemofilter to treat IMRD, hepatic failure, exogenous intoxication and other conditions associated with toxins in a patients blood. One treatment includes the use of a very large pore hemofilter to remove target complex molecules and/or target molecules from a patients blood and to infuse a replacement fluid into the patients blood to maintain a prescribed albumin concentration in the patients blood.

US Patent:

7291122, Nov 6, 2007

Filed:

May 12, 2004

Appl. No.:

10/843933

Inventors:

James R. Matson - Dallas TX, US

Assignee:

Immunocept, L.L.C. - Dallas TX

International Classification:

A61M 1/34
B01D 61/00
B01D 61/14

US Classification:

604 609, 210650, 210651, 210660, 604 401, 604 501, 604 504, 604 611

Abstract:

A hemofiltration system and method to treat an Inflammatory Mediator Related Disease in a mammal, including chronic and acute diseases, include a hemofilter and an adsorptive device. The hemofilter removes ultrafiltrate from a blood stream extracted from the mammal to create a filtered blood stream and an ultrafiltrate stream. The adsorptive device may include one or more adsorbent materials and may be used to adsorb inflammatory mediators from the ultrafiltrate stream received from the hemofilter to create a post adsorption ultrafiltrate stream. The post adsorption ultrafiltrate stream may be selectively combined with the filtered blood stream and together with the filtered blood stream may be returned to the mammal.

US Patent:

7520992, Apr 21, 2009

Filed:

Mar 23, 2006

Appl. No.:

11/387556

Inventors:

David Radunsky - Dallas TX, US
James R. Matson - Dallas TX, US
Patrice A. Lee - Erie CO, US

Assignee:

Imunocept, L.L.C. - Plano TX

International Classification:

B01D 61/00

US Classification:

210645, 2101952, 2103216, 210651, 210805, 604 501, 604 504, 604 609, 604 19

Abstract:

The present invention relates to a method and system for using a hemofilter to treat IMRD, hepatic failure, exogenous intoxication and other conditions associated with toxins in a patient's blood. One treatment includes the use of a very large pore hemofilter to remove target complex molecules and/or target molecules from a patient's blood and to infuse a replacement fluid into the patient's blood to maintain a prescribed albumin concentration in the patient's blood.

US Patent:

7524420, Apr 28, 2009

Filed:

Mar 8, 2004

Appl. No.:

10/796882

Inventors:

David Radunsky - Dallas TX, US
James R. Matson - Dallas TX, US
Patrice A. Lee - Erie CO, US

Assignee:

Immunocept, L.L.C. - Dallas TX

International Classification:

B01D 61/00

US Classification:

210645, 2101952, 210651, 210805, 2103216, 604 501, 604 504, 604 609, 604 19

Abstract:

The present invention relates to a method and system for using a hemofilter to treat IMRD, hepatic failure, exogenous intoxication and other conditions associated with toxins in a patient's blood. One treatment includes the use of a very large pore hemofilter to remove target complex molecules and/or target molecules from a patient's blood and to infuse a replacement fluid into the patient's blood to maintain a prescribed albumin concentration in the patient's blood. The replacement fluid may include pharmaceutical grade balanced salt solution containing albumin and/or other target receptor molecules and/or other physiological molecules in a sufficient concentration to adequately replenish ongoing losses.

US Patent:

7758533, Jul 20, 2010

Filed:

Nov 5, 2007

Appl. No.:

11/934978

Inventors:

James R. Matson - Dallas TX, US

Assignee:

Immunocept, L.L.C. - Dallas TX

International Classification:

B01D 61/00
A61M 1/34
A61M 1/14
A61K 38/00

US Classification:

604 609, 2101952, 2103216, 210650, 210651, 210660, 422 44, 514 1, 514 2, 604 401, 604 501, 604 504, 604 611

Abstract:

A hemofiltration system and method to treat an Inflammatory Mediator Related Disease in a mammal, including chronic and acute diseases, include a hemofilter and an adsorptive device. The hemofilter removes ultrafiltrate from a blood stream extracted from the mammal to create a filtered blood stream and an ultrafiltrate stream. The adsorptive device may include one or more adsorbent materials and may be used to adsorb inflammatory mediators from the ultrafiltrate stream received from the hemofilter to create a post adsorption ultrafiltrate stream. The post adsorption ultrafiltrate stream may be selectively combined with the filtered blood stream and together with the filtered blood stream may be returned to the mammal.

US Patent:

7837878, Nov 23, 2010

Filed:

Apr 17, 2009

Appl. No.:

12/425895

Inventors:

David Radunsky - Dallas TX, US
James R. Matson - Dallas TX, US
Patrice A. Lee - Erie CO, US

Assignee:

Immunocept, L.L.C. - Plano TX

International Classification:

B01D 61/00
A61K 38/38

US Classification:

210645, 210651, 4241301, 424529, 604 501, 604 601, 604 609, 604 19, 530362, 514 21, 514776

Abstract:

The present invention relates to a method and system for using a hemofilter to treat IMRD, hepatic failure, exogenous intoxication and other conditions associated with toxins in a patient's blood. One treatment includes the use of a very large pore hemofilter to remove target complex molecules and/or target molecules from a patient's blood and to infuse a replacement fluid into the patient's blood to maintain a prescribed albumin concentration in the patient's blood.