James Patrick Matthews

US Patent:

48788910, Nov 7, 1989

Filed:

Jun 25, 1987

Appl. No.:

7/067237

Inventors:

Millard M. Judy - Dallas TX
James L. Matthews - Dallas TX
Joseph T. Newman - Dallas TX

Assignee:

Baylor Research Foundation - Dallas TX

International Classification:

A61K 3900

US Classification:

604 5

Abstract:

A method for externally eradicating infectious pathogenic contaminants, such as enveloped viruses, bacteria, trypanosomal and malarial parasites, present in body tissues, such as blood, blood components, semen, skin, and cornea, before the treated body tisues are introduced into, or transplanted onto, the body of a human or an animal. Such method includes the steps of: (1) admixing an effective, non-toxic amount of photoactive compound, whch has a selectivity for binding to the infectious pathogenic biological contaminants present therein, with the body tissues outside the body to produce a resulting body tissues; (2) passing the resulting body tissues through an irradiating cell assembly, and (3) irradiating the resulting body tissues in the irradiating path of the cell assembly for an effective period of time with an effective level of radiation such that the radiation penetrates the resulting body tissues and eradicates the photoactive-compound-bound contaminants present in the resulting body tissues and produces a decontaminated body tissue suitable for introducing into, or transplanting onto, the body of a human or animal.

US Patent:

42139376, Jul 22, 1980

Filed:

Sep 22, 1976

Appl. No.:

5/726018

Inventors:

Francois A. Padovani - Dallas TX
Michael B. Miller - Richardson TX
James A. Moore - Dallas TX
James H. Fowler - both of, Plano TX
Malcom N. June - both of, Plano TX
James D. Matthews - Denver CO
T. R. Morton - Denver CO
Norbert A. Stotko - Denver CO
Lewis B. Palmer - Denver CO

Assignee:

Texas Instruments Incorporated - Dallas TX

International Classification:

B01J 818
C01B 3300

US Classification:

422142

Abstract:

A balanced, closed cycle silicon refinery system has been developed for producing electronic grade silicon from industrial grade silicon. Impurities comprising approximately 1% of the industrial grade silicon are removed in the refinery system to produce the purified silicon, while only a relatively small percentage of make-up chemicals are added to the system. In the refinery, hydrogen chloride is reacted with the impure silicon in a halide reactor to provide trichlorosilane and silicon tetrachloride and hydrogen. The trichlorosilane and/or silicon tetrachloride are passed through purification means, and then reacted with the hydrogen from the halide reactor in a fluidized bed reactor to produce the purified silicon and an effluent comprised of unreacted trichlorosilane, silicon tetrachloride, hydrogen, and the by-product hydrogen chloride. These materials are passed through a separator and the trichlorosilane and silicon tetrachloride and hydrogen are returned to the silicon reactor while the hydrogen chloride is returned to the halide reactor to be reacted with additional industrial grade silicon.

US Patent:

58073892, Sep 15, 1998

Filed:

Oct 18, 1994

Appl. No.:

8/324888

Inventors:

William W. Gardetto - Bedford TX
Millard M. Judy - Dallas TX
James L. Matthews - Dallas TX

Assignee:

MyriadLase, Inc. - Forest Hill TX

International Classification:

A61B 1732

US Classification:

606 17

Abstract:

An operating assembly for use in a liquid operating environment includes a flexible elongated light transmitting fiber having a light reflecting tip mounted thereon for reflecting the light beam laterally. The tip includes a number of features which minimize undesired heating of the tip. The tip is preferably made of solid gold and has a reflecting mirror surface coined on the gold tip. A lateral flushing passageway is disposed through the tip and allows surrounding ambient liquid to flow across the surface of the mirror to aid in cooling the tip and to aid in keeping the mirror clean. The tip is preferably mounted on the fiber by crimping. The tip includes a sufficient volume of material having a sufficient thermal conductivity located between the reflecting mirror and the crimped connection so as to dissipate heat energy which may be generated in the tip and to avoid sufficient heat energy reaching the crimped connection to cause a thermally induced failure of the mechanical attachment of the tip to the fiber at the crimp.

US Patent:

50302000, Jul 9, 1991

Filed:

Nov 6, 1989

Appl. No.:

7/433024

Inventors:

Millard M. Judy - Dallas TX
James L. Matthews - Dallas TX
Joseph T. Newman - Dallas TX

Assignee:

Baylor Research Foundation - Dallas TX

International Classification:

A61M 3700

US Classification:

604 5

Abstract:

A method for externally eradicating infectious pathogenic contaminants, such as enveloped viruses, bacteria, trypanosomal and malarial parasites, present in body tissues, such as blood, blood components, semen, skin, and cornea, before the treated body tissues are introduced into, or transplanted onto, the body of a human or an animal. Such method includes the steps of: (1) admixing an effective, non-toxic amount of photoactive compound, which has a selectively for binding to the infectious pathogenic biological contaminants present therein, with the body tissues outside the body to produce resulting body tissues; (2) maintaining the resulting body tissues in a suitable container in which there is no net mass transfer, and (3) irradiating the resulting body tissues in the container for an effective period of time with an effective level of radiation such that the radiation penetrates the resulting body tissues and eradicates the photoactive-compound-bound contaminants present in the resulting body tissues and produces a decontaminated body tissue suitable for introducing into, or transplanting onto, the body of a human or animal.

US Patent:

40924467, May 30, 1978

Filed:

Jul 31, 1974

Appl. No.:

5/494005

Inventors:

Francois A. Padovani - Dallas TX
Michael Brant Miller - Richardson TX
James A. Moore - Dallas TX
James H. Fowler - Plano TX
Malcolm Neville June - Plano TX
James D. Matthews - Denver CO
T. R. Morton - Denver CO
Norbert A. Stotko - Denver CO
Lewis B. Palmer - Denver CO

Assignee:

Texas Instruments Incorporated - Dallas TX

International Classification:

C01B 3300

US Classification:

427213

Abstract:

A balanced closed cycle silicon refinery has been developed for producing electronic silicon from industrial grade silicon. Impurities comprising approximately 1% of the industrial grade silicon are removed during the refinery process to produce the purified silicon, while only a relatively small percentage of make-up chemicals are added to the system. In the refinery, hydrogen chloride is reacted with the impure silicon in a halide reactor to provide trichlorosilane and silicon tetrachloride and hydrogen. The trichlorosilane and/or silicon tetrachloride are purified to remove the impurities, and then reacted with the hydrogen from the halide reactor in a fluidized bed reactor to produce the purified silicon and an effluent comprised of unreacted trichlorosilane, silicon tetrachloride, hydrogen, and the by-product hydrogen chloride. These materials are separated and the trichlorosilane and silicon tetrachloride and hydrogen are returned to the silicon reactor while the hydrogen chloride is returned to the halide reactor to be reacted with additional industrial grade silicon in a closed cycle process.

US Patent:

53706498, Dec 6, 1994

Filed:

Jan 13, 1994

Appl. No.:

8/180652

Inventors:

William W. Gardetto - Bedford TX
Millard M. Judy - Dallas TX
James L. Matthews - Dallas TX

Assignee:

MyriadLase, Inc. - Forest Hill TX

International Classification:

A61B 1736

US Classification:

606 17

Abstract:

An operating assembly for use in a liquid operating environment includes a flexible elongated light transmitting fiber having a light reflecting tip mounted thereon for reflecting the light beam laterally. The tip includes a number of features which minimize undesired heating of the tip. The tip is preferably made of solid gold and has a reflecting mirror surface coined on the gold tip. A lateral flushing passageway is disposed through the tip and allows surrounding ambient liquid to flow across the surface of the mirror to aid in cooling the tip and to aid in keeping the mirror clean. The tip is preferably mounted on the fiber by crimping. The tip includes a sufficient volume of material having a sufficient thermal conductivity located between the reflecting mirror and the crimped connection so as to dissipate heat energy which may be generated in the tip and to avoid sufficient heat energy reaching the crimped connection to cause a thermally induced failure of the mechanical attachment of the tip to the fiber at the crimp.

US Patent:

59654333, Oct 12, 1999

Filed:

May 29, 1996

Appl. No.:

8/652696

Inventors:

William W. Gardetto - Bedford TX
John K. Heacox - Mesquite TX
James L. Matthews - Dallas TX

Assignee:

Trans D.A.T.A. Service, Inc. - Houston TX

International Classification:

C12M 300

US Classification:

4352841

Abstract:

A portable perfusion/oxygenation module includes respiratory gas driven dual positive displacement pumps coupled to a stacked membrane oxygenator unit for perfusion fluid oxygenation, a valving manifold to control perfusate flow-direction coupled to an organ chamber designed to enable easy installation of organ and maintenance of intra and extra organ fluid pressure. All of the components and oxygen cylinders are fitted into an insulated chest capable of sustaining perfusion and oxygenation for 24 hours. The perfusion/oxygenation apparatus requires no electrical power, is compact with the total weight including the perfusion fluids and organ weighing less than 50 pounds. With low cumulative weight and the extremely low flow rate of gas required to pump the perfusate, the oxygen supply is capable of sustaining pumping operation for 24 hours without gas cylinder change. The dual pumps have axially aligned, commonly connected pistons using adjustable linkages that provide a simple and robust means of adjusting perfusate volume and pumping rate. No movable membranes, diaphragms or electrical power are required to deliver oxygenated perfusate.