James M Mcfarland

US Patent:

39975274, Dec 14, 1976

Filed:

Feb 17, 1976

Appl. No.:

5/658384

Inventors:

James W. McFarland - Lyme CT
Colin Thomson - Groton CT

Assignee:

Pfizer Inc. - New York NY

International Classification:

C07D49958

US Classification:

2602391

Abstract:

6-(Aminomethyl substituted phenyl- and thienylacetamido)-penicillanic acid and esters, and synthetic methods for the preparation thereof.

US Patent:

47974869, Jan 10, 1989

Filed:

Oct 14, 1987

Appl. No.:

7/108172

Inventors:

Edward A. Glazer - Waterford CT
James W. McFarland - Lyme CT

Assignee:

Pfizer Inc. - New York NY

International Classification:

C07D49504
C07D491048

US Classification:

544250

Abstract:

Certain trans-3-[3-(3-hydroxy-2-piperidyl)-2-oxopropyl]thieno[3,2-d]pyrimidin-4(3H )-one and furo[3,2-d]pyrimidin-4(3H)-one derivatives, a method of using same as anticoccidial agents, intermediates therefor, and a process for certain intermediates therefor.

US Patent:

39338436, Jan 20, 1976

Filed:

Dec 13, 1974

Appl. No.:

5/532496

Inventors:

Marwan J. Abu-El-Haj - Groton CT
James W. McFarland - Lyme CT

Assignee:

Pfizer Inc. - New York NY

International Classification:

C07D24906
C07D47104
C07D51304

US Classification:

260308A

Abstract:

A process for inhibiting plant growth comprising contacting a plant or its growth area with an effective amount of certain para-halophenyl substituted triazolines. A series of novel mesoionic para-halophenyl substituted triazolines. A novel process for preparing 3-phenyl-4-oxo-1,2,3-triazoline by contacting benzenediazoniumchloride and an. alpha. -amino carboxylic acid and cyclodehydrating the triazene produced using acetic anhydride and pyridine.

US Patent:

47255994, Feb 16, 1988

Filed:

Sep 8, 1986

Appl. No.:

6/913884

Inventors:

Edward A. Glazer - Waterford CT
James W. McFarland - Lyme CT

Assignee:

Pfizer Inc. - New York NY

International Classification:

C07D49504
C07D49704
A61K 31505

US Classification:

514258

Abstract:

Certain trans-3-[3-(3-hydroxy-2-piperidyl)-2-oxopropyl]thieno[3,2-d]pyrimidin-4(3H )-one and furo[3,2-d]pyrimidin-4(3H)-one derivatives, a method of using same as anticoccidial agents, intermediates therefor, and a process for certain intermediates therefor.

US Patent:

39391744, Feb 17, 1976

Filed:

Dec 13, 1974

Appl. No.:

5/532495

Inventors:

Marwan J. Abu-El-Haj - Groton CT
James W. McFarland - Lyme CT

Assignee:

Pfizer Inc. - New York NY

International Classification:

C07D24906
C07D47104
C07D51304

US Classification:

260308A

Abstract:

A process for inhibiting plant growth comprising contacting a plant or its growth area with an effective amount of certain para-halophenyl substituted triazolines. A series of novel mesoionic para-halophenyl substituted triazolines. A novel process for preparing 3-phenyl-4-oxo-1,2,3-triazoline by contacting benzenediazoniumchloride and an. alpha. -amino carboxylic acid and cyclodehydrating the triazene produced using acetic anhydride and pyridine.

US Patent:

40091600, Feb 22, 1977

Filed:

Feb 17, 1976

Appl. No.:

5/658489

Inventors:

James W. McFarland - Lyme CT
Colin Thomson - Groton CT

Assignee:

Pfizer Inc. - New York NY

International Classification:

C07D49958

US Classification:

2602391

Abstract:

6-(Aminomethyl substituted phenyl- and thienylacetamido)penicillanic acid and esters, and synthetic methods for the preparation thereof.

US Patent:

40026361, Jan 11, 1977

Filed:

Dec 13, 1974

Appl. No.:

5/532497

Inventors:

Marwan J. Abu-El-Haj - Groton CT
James W. McFarland - Lyme CT

Assignee:

Pfizer Inc. - New York NY

International Classification:

C07D51304

US Classification:

2603067T

Abstract:

A process for inhibiting plant growth comprising contacting a plant or its growth area with an effective amount of certain para-halophenyl substituted triazolines. A series of certain novel substituted tetrahydro-oxothiazolo-triazolium compounds useful as herbicides. A novel process for preparing 3-phenyl-4-oxo-1,2,3-triazoline by contacting benzenediazoniumchloride and an. alpha. -amino carboxylic acid and cyclodehydrating the triazene produced using acetic anhydride and pyridine.

US Patent:

39489116, Apr 6, 1976

Filed:

Nov 19, 1974

Appl. No.:

5/525183

Inventors:

James W. McFarland - Lyme CT

Assignee:

Pfizer Inc. - New York NY

International Classification:

C07D24144

US Classification:

260250QN

Abstract:

Compounds of the formula ##SPC1## Wherein X is a 6- or 7-position substituent selected from the group consisting of formyl, acetyl, hydroxymethyl, 1-hydroxyethyl and ##EQU1## wherein Y is selected from the group consisting of hydrogen and methyl; R. sub. 1 is hydrogen or methyl; R. sub. 2, when taken separately, is hydrogen or alkyl having 1 to 4 carbon atoms; R. sub. 3, when taken separately, is hydrogen, alkyl having 1 to 4 carbon atoms, --(CH. sub. 2). sub. n OH, --(CH. sub. 2). sub. n OCH. sub. 3, --(CH. sub. 2). sub. n NH. sub. 2, ##EQU2## or ##EQU3## wherein n is 2 or 3 and R. sub. 2 and R. sub. 3, when taken together with the nitrogen atom to which they are attached, form a member selected from the group consisting of pyrrolo, pyrrolidino, piperidino, morpholino, thiomorpholino, piperazino, N-(lower alkyl)piperazino, N-hydroxy(lower alkyl)piperazino, N-(lower alkanoyl)piperazino and N-carbo(lower alkoxy)piperazino and the pharmaceutically acceptable acid addition salts of those compounds wherein R. sub. 2 has an. omega. -aminoalkyl moiety; methods for their preparation; and their use as antibacterial agents and as agents for promoting growth and improving feed efficiency of animals.