James B Patrick

US Patent:

6677322, Jan 13, 2004

Filed:

Jan 16, 2002

Appl. No.:

10/050396

Inventors:

Joel A. Sequeira - Scotch Plains NJ
Francis M. Cuss - Basking Ridge NJ
Keith B. Nolop - Millburn NJ
Imtiaz A. Chaudry - North Caldwell NJ
Nagamani Nagabhushan - Parsippany NJ
James E. Patrick - Belle Mead NJ
Mitchell Cayen - Bedminster NJ

Assignee:

Schering Corporation - Kenilworth NJ

International Classification:

A61K 3156

US Classification:

514169, 514172, 514176, 514182, 514826, 514958

Abstract:

The administration of aerosolize particles of mometasone furoate in the form of dry powders, solutions, or aqueous suspension for treating corticosteroid-responsive diseases of the surfaces of upper and/or lower airway passages and/or lungs, e. g. , allergic rhinitis and asthma is disclosed.

US Patent:

6982251, Jan 3, 2006

Filed:

Jun 11, 2002

Appl. No.:

10/166942

Inventors:

Anima Ghosal - Edison NJ, US
Shmuel Zbaida - East Brunswick NJ, US
Swapan K. Chowdhury - Warren NJ, US
Robert M. Iannucci - Hampton NJ, US
Wenqing Feng - Chatham NJ, US
Kevin B. Alton - Cedar Knolls NJ, US
James E. Patrick - Belle Mead NJ, US
Harry R. Davis - Berkeley Heights NJ, US

Assignee:

Schering Corporation - Kenilworth NJ

International Classification:

A61K 31/7056
A61K 31/397
A61K 31/675
C07H 17/02
C07D 25/08

US Classification:

514 23, 514 79, 51421002, 536 174, 540200

Abstract:

Hypocholesterolemic substituted 2-azetidinone compounds of the formula: are disclosed, as well as a methods of lowering cholesterol by administering said compounds, pharmaceutical compositions containing them, and the combination of a substituted 2-azetidinone cholesterol-lowering agent and a cholesterol biosynthesis inhibitor for the treatment and prevention of atherosclerosis.

US Patent:

7312223, Dec 25, 2007

Filed:

Jul 29, 2004

Appl. No.:

10/901574

Inventors:

Anima Ghosal - Edison NJ, US
Wei Tong - New City NY, US
Swapan K. Chowdhury - Warren NJ, US
Shmuel Zbaida - East Brunswick NJ, US
Mark A. Wirth - Neshanic Station NJ, US
Kevin B. Alton - Cedar Knolls NJ, US
James E. Patrick - Aiken SC, US
Craig D. Boyle - Branchburg NJ, US
Andrew Stamford - Chatham Township NJ, US

Assignee:

Schering Corporation - Kenilworth NJ

International Classification:

C07D 473/06
A61K 31/522
A61P 9/10
A61P 9/12

US Classification:

51426334, 544271, 544272, 51426335, 51426336

Abstract:

The present invention is directed to a metabolite of a xanthine Phosphodiesterase type 5 inhibitor having the following structureFurther disclosed are methods of treating a physiological disorder, symptom or disease in a patient, comprising administering to the patient an effective amount of the above compound, wherein the physiological disorder, symptom or disease is a urogenital, cardiovascular, cerebrovascular or peripheral vascular disorder, angina pectoris, hypertension, restenosis post angioplasty, endarterectomy, stent introduction, cerebral stroke, a respiratory tract disorder such as an allergic condition associated with atopy, pulmonary hypertension, an ischemic heart disorder, impaired glucose tolerance, diabetes and its related complication, insulin resistance syndrome, hyperglycemia, polycystic ovarian syndrome, a glomerular disorder, renal insufficiency, nephritis, a tubular interstitial disorder, an autoimmune disorder, glaucoma, intestinal motility, cachexia or cancer.

US Patent:

20020127187, Sep 12, 2002

Filed:

Jan 16, 2002

Appl. No.:

10/053204

Inventors:

Joel Sequeira - Scotch Plains NJ, US
Francis Cuss - Basking Ridge NJ, US
Keith Nolop - Millburn NJ, US
Imtiaz Chaudry - North Caldwell NJ, US
Nagamani Nagabhushan - Parsippany NJ, US
James Patrick - Belle Mead NJ, US
Mitchell Cayen - Bedminster NJ, US

International Classification:

A61L009/04
A61K009/14
A61K031/58

US Classification:

424/046000, 514/172000

Abstract:

The administration of aerosolize particles of mometasone furoate in the form of dry powders, solutions, or aqueous suspension for treating corticosteroid-responsive diseases of the surfaces of upper and/or lower airway passages and/or lungs, e.g., allergic rhinitis and asthma is disclosed.

US Patent:

20020137690, Sep 26, 2002

Filed:

Dec 17, 2001

Appl. No.:

10/023295

Inventors:

Anima Ghosal - Edison NJ, US
Shmuel Zbaida - East Brunswick NJ, US
Swapan Chowdhury - Warren NJ, US
Robert Iannucci - Hampton NJ, US
Wenqing Feng - Chatham NJ, US
Kevin Alton - Cedar Knolls NJ, US
James Patrick - Belle Mead NJ, US
Harry Davis - Berkeley Heights NJ, US

Assignee:

Schering Corporation

International Classification:

A61K031/7056
C07H017/02

US Classification:

514/023000, 536/017400

Abstract:

please check closely-very confusing Hypocholesterolemic sugar-substituted 2-azetidinone compounds of the formula: are disclosed, as well as a method of lowering cholesterol by administering said compounds, pharmaceutical compositions containing them, and the combination of a sugar-substituted 2-azetidinone cholesterol-lowering agent and a cholesterol biosynthesis inhibitor for the treatment and prevention of atherosclerosis.

US Patent:

20030216365, Nov 20, 2003

Filed:

Apr 30, 2003

Appl. No.:

10/426329

Inventors:

Joel Sequeira - Scotch Plains NJ, US
Francis Cuss - Basking Ridge NJ, US
Keith Nolop - Millburn NJ, US
Imtiaz Chaudry - North Caldwell NJ, US
Nagamani Nagabhushan - Parsippany NJ, US
James Patrick - Belle Mead NJ, US
Mitchell Cayen - Bedminster NJ, US

International Classification:

A61K031/573
A61L009/04

US Classification:

514/179000, 424/045000

Abstract:

The administration of aerosolize particles of mometasone furoate in the form of dry powders, solutions, or aqueous suspension for treating corticosteroid-responsive diseases of the surfaces of upper and/or lower airway passages and/or lungs, e.g., allergic rhinitis and asthma is disclosed.