Kerry Bradley - Glendale CA, US James R. Thacker - Eureka MO, US
Assignee:
Advanced Bionics Corporation - Valencia CA
International Classification:
A61N 1/00
US Classification:
607 2
Abstract:
Interelectrode impedance or electric field potential measurements are used to determine the relative orientation of one lead to other leads in the spinal column or other body/tissue location. Interelectrode impedance is determined by measuring impedance vectors. The value of the impedance vector is due primarily to the electrode-electrolyte interface, and the bulk impedance between the electrodes. The bulk impedance between the electrodes is, in turn, made up of (1) the impedance of the tissue adjacent to the electrodes, and (2) the impedance of the tissue between the electrodes. In one embodiment, the present invention makes both monopolar and bipolar impedance measurements, and then corrects the bipolar impedance measurements using the monopolar measurements to eliminate the effect of the impedance of the tissue adjacent the electrodes. The orientation and position of the leads may be inferred from the relative minima of the corrected bipolar impedance values. These corrected impedance values may also be mapped and stored to facilitate a comparison with subsequent corrected impedance measurement values.
Todd K Whitehurst - Santa Clarita CA, US Kelly H. McClure - Simi Valley CA, US James R Thacker - Eureka MO, US James P McGivern - Stevenson Ranch CA, US
Assignee:
Advanced Bionics Corporation - Valencia CA
International Classification:
A61N 1/18
US Classification:
607 44, 6048911, 607 3
Abstract:
Treatment of hypertension includes implantation of the discharge portion(s) of a catheter and/or electrical stimulation electrode(s) adjacent the tissue(s) to be stimulated. Stimulation pulses, i. e. , drug infusion pulses and/or electrical pulses, are supplied by one or more implanted stimulators, through the catheter and possibly also a lead, tunneled subcutaneously between the stimulator and stimulation site. A microstimulator(s) may also/instead deliver electrical stimulation pulses. Stimulation sites include the carotid sinus and carotid body, among other locations. Treatments include drugs used for acute and/or chronic treatment of hypertension. In a number of embodiments, a need for or response to treatment is sensed, and the electrical and/or infusion pulses adjusted accordingly.
Implantable System Having Rechargeable Battery Indicator
Carla Mann Woods - Los Angeles CA, US James R Thacker - Eureka MO, US David K. L Peterson - Saugus CA, US
Assignee:
Advanced Bionics Corporation - Sylmar CA
International Classification:
A61N 1/378
US Classification:
607 29, 607 33, 607 61
Abstract:
A system and method for detecting the status of a rechargeable battery included within an implantable medical device. The medical device can incorporate a status indicator which signals the user concerning the battery status, e. g. , low battery level. The signal may be audible or it may arise from an electrical stimulation that is perceptually distinguished from the operative, therapeutic stimulation. The external programmer may also incorporate a second battery status indicator that is visual, audible, or physically felt. Battery status data may be conveyed on visual displays on the external programmer by uploading this information from the medical device using a bi-directional telemetry link. Such battery status data are helpful to the user to indicate when the battery should be recharged and to the clinician to monitor patient compliance and to determine end-of-useful life of the rechargeable battery.
Neural Stimulation System Providing Auto Adjustment Of Stimulus Output As A Function Of Sensed Impedance
John D H King - Sherman Oaks CA, US James R Thacker - Eureka MO, US
Assignee:
Boston Scientific Scimed, Inc. - Maple Grove MN
International Classification:
A61N 1/00
US Classification:
607 62, 607 8, 607 11, 607 27, 600547
Abstract:
A neural stimulation system automatically corrects or adjusts the stimulus magnitude (stimulation energy) in order to maintain a comfortable and effective stimulation therapy. Because the changes in impedance associated with the electrode-tissue interface can indicate obstruction of current flow and positional lead displacement, lead impedance can indicate the quantity of electrical stimulation energy that should be delivered to the target neural tissue to provide corrective adjustment. Hence, a change in impedance or morphology of an impedance curve may be used in a feedback loop to indicate that the stimulation energy needs to be adjusted and the system can effectively auto correct the magnitude of stimulation energy to maintain a desired therapeutic effect.
Apparatus And Method For Determining The Relative Position And Orientation Of Neurostimulation Leads
Kerry Bradley - Glendale CA, US James R. Thacker - Eureka MO, US
Assignee:
Boston Scientific Neuromodulation Corporation - Valenica CA
International Classification:
A61N 1/00
US Classification:
607 62, 607117
Abstract:
Interelectrode impedance or electric field potential measurements are used to determine the relative orientation of one lead to other leads in the spinal column or other body/tissue location. Interelectrode impedance is determined by measuring impedance vectors. The value of the impedance vector is due primarily to the electrode-electrolyte interface, and the bulk impedance between the electrodes. The bulk impedance between the electrodes is, in turn, made up of (1) the impedance of the tissue adjacent to the electrodes, and (2) the impedance of the tissue between the electrodes. In one embodiment, the present invention makes both monopolar and bipolar impedance measurements, and then corrects the bipolar impedance measurements using the monopolar measurements to eliminate the effect of the impedance of the tissue adjacent the electrodes. The orientation and position of the leads may be inferred from the relative minima of the corrected bipolar impedance values. These corrected impedance values may also be mapped and stored to facilitate a comparison with subsequent corrected impedance measurement values.
Neural Stimulation System Providing Auto Adjustment Of Stimulus Output As A Function Of Sensed Impedance
John D. H. King - Sherman Oaks CA, US James R. Thacker - Eureka CA, US
Assignee:
Boston Scientific Neuromodulation Corporation - Valencia CA
International Classification:
A61N 1/08
US Classification:
607 62, 607 8, 607 11, 607 27, 600547
Abstract:
A neural stimulation system automatically corrects or adjusts the stimulus magnitude (stimulation energy) in order to maintain a comfortable and effective stimulation therapy. Because the changes in impedance associated with the electrode-tissue interface can indicate obstruction of current flow and positional lead displacement, lead impedance can indicate the quantity of electrical stimulation energy that should be delivered to the target neural tissue to provide corrective adjustment. Hence, a change in impedance or morphology of an impedance curve may be used in a feedback loop to indicate that the stimulation energy needs to be adjusted and the system can effectively auto correct the magnitude of stimulation energy to maintain a desired therapeutic effect.
Apparatus And Method For Determining The Relative Position And Orientation Of Neurostimulation Leads
Kerry Bradley - Glendale CA, US James Thacker - Eureka MO, US Michael Moffitt - Valencia CA, US
Assignee:
Boston Scientific Neuromodulation Corporation - Valencia CA
International Classification:
A61N 1/00
US Classification:
607 62, 607 2, 607117
Abstract:
A method for determining whether the relative position of electrodes used by a neurostimulation system has changed within a patient comprises determining the amplitude of a field potential at each of at least one of the electrodes, determining if a change in each of the determined electric field amplitudes has occurred, and analyzing the change in each of the determined electric field amplitudes to determine whether a change in the relative position of the electrodes has occurred. Another method comprises measuring a first monopolar impedance between a first electrode and a reference electrode, measuring a second monopolar impedance between second electrode and the reference electrode, measuring a bipolar impedance between the first and second electrodes, and estimating an amplitude of a field potential at the second electrode based on the first and second monopolar impedances and the bipolar impedance.
Todd K Whitehurst - Santa Clarita CA, US Kelly H McClure - Simi Valley CA, US James R Thacker - Eureka MO, US
Assignee:
Boston Scientific Neuromodulation Corporation - Valencia CA
International Classification:
A61N 1/08
US Classification:
607 3
Abstract:
Method and systems of treating a patient with at least one of a myocardial infarction, a stroke, and a pulmonary embolism include providing a stimulator coupled to at least one electrode and a catheter, configuring one or more stimulation parameters to treat at least one of a myocardial infarction, a stroke, and a pulmonary embolism, programming the stimulator with the one or more stimulation parameters, delivering with the stimulator via the catheter at least one drug to at least one tissue in accordance with the one or more stimulation parameters, and limiting perfusion of the at least one tissue by delivering electrical stimulation with the stimulator via the at least one electrode to the at least one tissue.
Stanley Weinberg, Dawn Moore, C Markley, Shirley Lloyd, Dennis Dyer, Barbara Mills, Betty Shelton, Carl Perdue, Jeannine Kittinger, Joyce Sink, David Barranger, Harold Hall
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