Recombinant proteins have been developed for the immunization of animals against cryptosporidiosis. The proteins are effective for the immunization of a variety of animals against , particularly for the production of hyperimmune colostrum that may be used to confer passive immunity against the parasite. Isolated DNA sequences which encode these proteins have also been developed. The DNA sequences may be inserted into recombinant DNA molecules such as cloning vectors or expression vectors for the transformation of cells and the production of the proteins.
Recombinant proteins have been developed for the immunization of animals against cryptosporidiosis. The proteins are effective for the immunization of a variety of animals against , particularly for the production of hyperimmune colostrum that may be used to confer passive immunity against the parasite. Isolated DNA sequences which encode these proteins have also been developed. The DNA sequences may be inserted into recombinant DNA molecules such as cloning vectors or expression vectors for the transformation of cells and the production of the proteins.
Cloning And Expression Of A Dna Sequence Encoding A 41 Kda Cryptosporidium Parvum Oocyst Wall Protein
Mark C. Jenkins - Davidsonville MD Ron Fayer - Columbia MD James Trout - Columbia MD
Assignee:
The United States of America as represented by the Secretary of Agriculture - Washington DC
International Classification:
C07H 2102
US Classification:
536 231
Abstract:
Recombinant proteins have been developed for the immunization of animals against cryptosporidiosis. The proteins are effective for the immunization of a variety of animals against Cryptosporidium parvum, particularly for the production of hyperimmune colostrum that may be used to confer passive immunity against the parasite. Isolated DNA sequences which encode these proteins have also been developed. The DNA sequences may be inserted into recombinant DNA molecules such as cloning vectors or expression vectors for the transformation of cells and the production of the proteins.
Office of Research Oversight U.s Department of Veterans Affairs Jun 2008 - Nov 2015
Health Science Specialist
Office of Research Oversight U.s Department of Veterans Affairs Jun 2008 - Nov 2015
Director, Research Safety and Animal Welfare
Usda Aug 1993 - May 2008
Research Scientist
Education:
Penn State University 1985 - 1992
Master of Science, Doctorates, Masters, Doctor of Philosophy, Physiology
Penn State University 1979 - 1983
Bachelors, Bachelor of Science, Biology
Mike Shepherd, Delynne Miller, Susan Hood, Kristi Jenkins, Stephanie Pryor, Susan Dobrisky, Nick Henning, Brock Williams, Melinda Gibson, David Walker, Amanda Rogers