Jane E Yang

US Patent:

7393522, Jul 1, 2008

Filed:

Sep 3, 2003

Appl. No.:

10/655493

Inventors:

Ramin Najafi - Novato CA, US
Lu Wang - Emeryville CA, US
Mansour Bassiri - Davis CA, US
Jane Yang - Emeryville CA, US

Assignee:

NovaBay Pharmaceuticals, Inc. - Emeryville CA

International Classification:

A61K 31/74
A61K 33/40
A61K 33/14

US Classification:

424 7804, 424 7806, 424 7807, 424613, 424661

Abstract:

Described herein is a physiologically-balanced, acidic solution. Typically the solution is prepared by a chemical reactions or by the electrolysis of a solution comprising a mixture of an inorganic salt to form a physiologically balanced solution. This invention also relates to methods for use of the solutions, including a specialized bandage which may be used in combination with the solutions, or optionally with other topically applied materials. A mixture of inorganic salts and, optionally minerals, is used in order to mimic the electrolyte concentration and mixture of body fluid in an isotonic state. The solution typically comprises of one halide salt of lithium, sodium, potassium, calcium, and other cations. Typically the halide is fluoride, chloride, bromide, or iodide, and most typically chloride. A typical electrolyzed solution of the present invention has a pH within the range of about 2 to about 5, an oxidation reduction potential within the range of about +600 mV to about +1200 mV, and hypohalous acid concentration in the range of about 10 ppm to about 200 ppm.

US Patent:

7462361, Dec 9, 2008

Filed:

Aug 17, 2004

Appl. No.:

10/920636

Inventors:

Mansour Bassiri - Davis CA, US
Ramin Najafi - Novato CA, US
Lu Wang - Emeryville CA, US
Jane Yang - Emeryville CA, US

Assignee:

Novabay Pharmaceuticals, Inc. - Emeryville CA

International Classification:

A61K 9/54
C07C 69/86

US Classification:

424400, 560 66

Abstract:

The present invention relates to active bactericidal, antibacterial, anti-infective, antimicrobial, sporicidal, disinfectant, antifungal and antiviral compounds and compositions and to new uses of these compositions in therapy. This specification also describes methods of use for the new compounds and compositions. The specification further describes methods for preparing these compounds.

US Patent:

7893109, Feb 22, 2011

Filed:

Sep 11, 2008

Appl. No.:

12/209002

Inventors:

Mansour Bassiri - Novato CA, US
Ramin Najafi - Novato CA, US
Lu Wang - Moraga CA, US
Jane Yang - Emeryville CA, US

Assignee:

Novabay Pharmaceuticals, Inc. - Emeryville CA

International Classification:

A61K 31/13
A61K 31/66
C07C 309/03

US Classification:

514612, 514578, 562104, 562105

Abstract:

The present invention relates to active bactericidal, antibacterial, anti-infective, antimicrobial, sporicidal, disinfectant, antifungal and antiviral compounds and compositions and to new uses of these compositions in therapy. This specification also describes methods of use for the new compounds and compositions. The specification further describes methods for preparing these compounds.

US Patent:

20080279963, Nov 13, 2008

Filed:

Mar 21, 2008

Appl. No.:

12/053536

Inventors:

Ramin Najafi - Novato CA, US
Lu Wang - Emeryville CA, US
Mansour Bassiri - Emeryville CA, US
Jane Yang - Emeryville CA, US

International Classification:

A61K 33/14
A61P 17/02

US Classification:

424661

Abstract:

Described herein is a physiologically-balanced, acidic solution. Typically the solution is prepared by a chemical reactions or by the electrolysis of a solution comprising a mixture of an inorganic salt to form a physiologically balanced solution. This invention also relates to methods for use of the solutions, including a specialized bandage which may be used in combination with the solutions, or optionally with other topically applied materials. A mixture of inorganic salts and, optionally minerals, is used in order to mimic the electrolyte concentration and mixture of body fluid in an isotonic state. The solution typically comprises of one halide salt of lithium, sodium, potassium, calcium, and other cations. Typically the halide is fluoride, chloride, bromide, or iodide, and most typically chloride. A typical electrolyzed solution of the present invention has a pH within the range of about 2 to about 5, an oxidation reduction potential within the range of about +600 mV to about +1200 mV, and hypohalous acid concentration in the range of about 10 ppm to about 200 ppm. The solution has bactericidal, fungicidal, and sporicidal properties. The composition of the invention is nontoxic and has antibacterial properties, and is useful in any application in which antimicrobial properties are desirable.