The present disclosure relates to N-benzyl pyrrole compounds of formula (I) useful as inhibitors of the enzyme Fatty Acid Amide Hydrolase (FAAH). The disclosure also provides pharmaceutically acceptable compositions comprising the compounds of the disclosure and methods of using the compositions in the treatment or prevention of various disorders.
Joel Moore - Lexington MA, US James Jia - Somerville MA, US Takashi Nakai - Newton MA, US Charles Kim - Cambridge MA, US Thomas Wai-Ho Lee - Lexington MA, US Jane Yang - Andover MA, US
Compounds of Formula I are described. They are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds may be useful for treating, preventing or managing various disorders that are herein disclosed.
Colleen Hudson - Malden MA, US Timothy C. Barden - Salem MA, US James Jia - Somerville MA, US Ara Mermerian - Melrose MA, US Bo Peng - Arlington MA, US Jane Yang - Boxborough MA, US Xiang Y. Yu - Acton MA, US Kevin Sprott - Needham MA, US Angelika Fretzen - Somerville MA, US
The present disclosure relates to compounds useful as inhibitors of the enzyme Fatty Acid Amide Hydrolase (FAAH). The disclosure also provides pharmaceutically acceptable compositions comprising the compounds of the disclosure and methods of using the compositions in the treatment or prevention of various disorders. Compounds of the invention are described in Table 1.
Jan 2012 to 2000 Finance AssociateAHG RECYCLING, INC Cupertino, CA Jan 2012 to Jun 2012 KRIS WANG FOR SANTA CLARA COUNTY SUPERVISORDEPARTMENT OF RESIDENTIAL LIFE Baton Rouge, LA Aug 2010 to May 2011 Business Office Assistant of the Edward Gay Apartment ComplexDEPARTMENT OF RESIDENTIAL LIFE Baton Rouge, LA Aug 2010 to Jan 2011 Lab Teaching Assistant / TutorDEPARTMENT OF THE TREASURY, INTERNAL REVENUE SERVICE Baton Rouge, LA Mar 2010 to May 2010 VITA and TCE Programs Volunteer
Education:
LOUISIANA STATE UNIVERSITY Baton Rouge, LA 2007 to 2011 B.S. in Accounting
Skills:
MS Word, Excel, PowerPoint, Quickbooks, Microsoft Dynamics Great Plains, Basic SAS program, Real estate valuation,Bilingual
Medicine Doctors
Dr. Jane Y Yang, San Francisco CA - MD (Doctor of Medicine)
2200 Ofarrell St, San Francisco, CA 94115 4158332000 (Phone)
Valley Radiologists Medical Grp 2581 Samaritan Dr Suite 415, San Jose, CA 95124 4083586881 (Phone)
2238 Geary Blvd, San Francisco, CA 94115 4158332000 (Phone)
450 6Th Ave, San Francisco, CA 94118 4158332202 (Phone)
Certifications:
Otolaryngology, 2000
Awards:
Healthgrades Honor Roll
Languages:
English Spanish
Hospitals:
2200 Ofarrell St, San Francisco, CA 94115
2238 Geary Blvd, San Francisco, CA 94115
450 6Th Ave, San Francisco, CA 94118
Valley Radiologists Medical Grp 2581 Samaritan Dr Suite 415, San Jose, CA 95124
Good Samaritan Hospital 2425 Samaritan Drive, San Jose, CA 95124
John Muir Medical Center - Concord 2540 East Street, Concord, CA 94520
Kaiser Permanente San Francisco Medical Center 2425 Geary Boulevard, San Francisco, CA 94115
Education:
Medical School University of Missouri / Columbia Campus Graduated: 1993 Medical School University Of California, Davis Graduated: 1993 Medical School University Of Washington Graduated: 1993
Dr. Jane M Yang, Boston MA - MD (Doctor of Medicine)
UCLA Medical GroupUCLA Gonda Goldschmeid Vascular Center 200 Ucla Medical Plz, Los Angeles, CA 90095 3102066294 (phone), 3107949603 (fax)
Education:
Medical School Columbia University College of Physicians and Surgeons Graduated: 2006
Languages:
English Spanish
Description:
Dr. Yang graduated from the Columbia University College of Physicians and Surgeons in 2006. She works in Los Angeles, CA and specializes in Vascular Surgery. Dr. Yang is affiliated with Ronald Reagan UCLA Medical Center and Santa Monica UCLA Medical Center.
Otolaryngology Plastic Surgery within the Head & Neck Plastic Surgery Within the Head and Neck
Work:
San Francisco Veterans Affairs Medical Center
450 6Th Ave, San Francisco, CA 94118 UC Davis Professional Services
2221 Stockton Blvd, Sacramento, CA 95817
Jane Yang (2000-2003), Matt Parrish (2004-2007), Davis Park (2000-2003), Mary Ann Horcher (1978-1981), Ray Maiello (1993-1996), Michael Homison (2003-2006)