Disclosed herein are compounds that inhibit Hsp90 interactions with IAP proteins, such as Survivin, XIAP, cIAP1, or cIAP2, and methods for identifying and using such compounds.
Detection Of Survivin In The Biological Fluids Of Cancer Patients
Dario C. Altieri - Worcester MA, US Robert M. Weiss - North Haven CT, US Shannon D. Smith - Guilford CT, US Marcia A. Wheeler - Branford CT, US Janet Plescia - Meriden CT, US
The present invention includes a method for diagnosing cancer and predicting recurrent cancer comprising detecting the presence of survivin in the biological fluid of a patient. The present invention also provides kits comprising one or more agents that detect survivin polypeptide or survivin nucleic acid and a container for collecting biological fluid for testing.
Detection Of Survivin In The Biological Fluids Of Cancer Patients
Dario Altieri - Worcester MA, US Robert Weiss - North Haven CT, US Shannon Smith - Guilford CT, US Victor Morris, legal representative - Guilford CT, US Marcia Wheeler - Branford CT, US Janet Plescia - Meriden CT, US
The present invention includes a method for diagnosing cancer comprising detecting the presence of survivin in the biological fluid of a patient. The present invention also provides kits comprising one or more agents that detect survivin polypeptide or survivin nucleic acid and a container for collecting biological fluid for testing.
Compounds That Inhibit Hsp90 Protein-Protein Interactions With Iap Proteins
Disclosed herein are compounds that inhibit Hsp90 interactions with IAP proteins, such as Survivin, XIAP, cIAP1, or cIAP2, and methods for identifying and using such compounds.
Detection Of Survivin In The Biological Fluids Of Cancer Patients
Dario Altieri - Hamden CT, US Robert Weiss - North Haven CT, US Shannon Smith - , US Victor Morris - Guilford CT, US Marcia Wheeler - Branford CT, US Janet Plescia - Meriden CT, US
International Classification:
C12Q001/68 G01N033/574
US Classification:
435/006000, 435/007230
Abstract:
The present invention includes a method for diagnosing cancer comprising detecting the presence of survivin in the biological fluid of a patient. The present invention also provides kits comprising one or more agents that detect survivin polypeptide or survivin nucleic acid and a container for collecting biological fluid for testing.
Compounds That Inhibit Hsp90 Protein-Protein Interactions With Iap Proteins
Disclosed herein are compounds that inhibit Hsp90 interactions with IAP proteins, such as Survivin, XIAP, cIAP1, or cIAP2, and methods for identifying and using such compounds.
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