Janet Reber

US Patent:

6599331, Jul 29, 2003

Filed:

Jul 1, 2002

Appl. No.:

10/185869

Inventors:

Don J. Chandler - Austin TX
Beth A. Lambert - Austin TX
Janet J. Reber - Austin TX
Stacie L. Phipps - Midlothian TX

Assignee:

Luminex Corporation - Austin TX

International Classification:

D06P 190

US Classification:

8611, 8607, 8614, 8617, 8638, 8648

Abstract:

An improved method of making a series of bead or microsphere or particle populations characterized by subtle variation in a proportion or ratio of at least two fluorescent dyes distributed within a single bead of each population is provided. These beads, when excited by a single excitation light source are capable of giving off several fluorescent signals simultaneously. A set containing as many as 64 distinct populations of multicolored, fluorescent beads is provided and when combined with analytical reagents bound to the surface of such beads is extremely useful for multiplexed analysis of a plurality of analytes in a single sample. Thus, methods of staining polymeric particles, the particles themselves, and methods of using such particles are claimed.

US Patent:

6632526, Oct 14, 2003

Filed:

Oct 14, 1998

Appl. No.:

09/172174

Inventors:

Don J. Chandler - Austin TX
Van S. Chandler - Austin TX
Beth A. Lambert - Austin TX
Janet J. Reber - Austin TX
Stacie L. Phipps - Austin TX

Assignee:

Luminex Corporation - Austin TX

International Classification:

B32B 500

US Classification:

428402, 42840224, 428403, 428407, 428690, 8607, 8611, 8614, 8617, 8638, 8648, 436523, 436531, 436533, 436534, 25230116, 25230135

Abstract:

An improved method of making a series of bead or microsphere or particle populations characterized by subtle variation in a proportion or ratio of at least two fluorescent dyes distributed within a single bead of each population is provided. These beads, when excited by a single excitation light source are capable of giving off several fluorescent signals simultaneously. A set containing as many as 64 distinct populations of multicolored, fluorescent beads is provided and when combined with analytical reagents bound to the surface of such beads is extremely useful for multiplexed analysis of a plurality of analytes in a single sample. Thus, methods of staining polymeric particles, the particles themselves, and methods of using such particles are claimed.

US Patent:

6929859, Aug 16, 2005

Filed:

Jul 3, 2003

Appl. No.:

10/401549

Inventors:

Don J. Chandler - Austin TX, US
Van S. Chandler - Austin TX, US
Beth A. Lambert - Austin TX, US
Janet J. Reber - Austin TX, US
Stacie L. Phipps - Austin TX, US

International Classification:

B32B005/16

US Classification:

428403, 427222

Abstract:

An improved method of making a series of bead or microsphere or particle populations characterized by subtle variation in a proportion or ratio of at least two fluorescent dyes distributed within a single bead of each population is provided. These beads, when excited by a single excitation light source are capable of giving off several fluorescent signals simultaneously. A set containing as many as 64 distinct populations of multicolored, fluorescent beads is provided and when combined with analytical reagents bound to the surface of such beads is extremely useful for multiplexed analysis of a plurality of analytes in a single sample. Thus, methods of staining polymeric particles, the particles themselves, and methods of using such particles are claimed.

US Patent:

7445844, Nov 4, 2008

Filed:

Aug 2, 2005

Appl. No.:

11/195185

Inventors:

Don J. Chandler - Austin TX, US
Van S. Chandler - Austin TX, US
Beth A. Lambert - Austin TX, US
Janet J. Reber - Austin TX, US
Stacie L. Phipps - Austin TX, US

Assignee:

Luminex Corporation - Austin TX

International Classification:

B32B 5/16

US Classification:

428403, 427222

Abstract:

An improved method of making a series of bead or microsphere or particle populations characterized by subtle variation in a proportion or ratio of at least two fluorescent dyes distributed within a single bead of each population is provided. These beads, when excited by a single excitation light source are capable of giving off several fluorescent signals simultaneously. A set containing as many as 64 distinct populations of multicolored, fluorescent beads is provided and when combined with analytical reagents bound to the surface of such beads is extremely useful for multiplexed analysis of a plurality of analytes in a single sample. Thus, methods of staining polymeric particles, the particles themselves, and methods of using such particles are claimed.

US Patent:

6514295, Feb 4, 2003

Filed:

Apr 13, 1999

Appl. No.:

09/290248

Inventors:

Don J. Chandler - Austin TX
Beth A. Lambert - Austin TX
Janet J. Reber - Austin TX
Stacie L. Phipps - Austin TX

Assignee:

Luminex Corporation - Austin TX

International Classification:

D06P 190

US Classification:

8607, 8611, 8614, 8617, 8638, 8648

Abstract:

An improved method of making a series of bead or microsphere or particle populations characterized by subtle variation in a proportion or ratio of at least two fluorescent dyes distributed within a single bead of each population is provided. These beads, when excited by a single excitation light source are capable of giving off several fluorescent signals simultaneously. A set containing as many as 64 distinct populations of multicolored, fluorescent beads is provided and when combined with analytical reagents bound to the surface of such beads is extremely useful for multiplexed analysis of a plurality of analytes in a single sample. Thus, methods of staining polymeric particles, the particles themselves, and methods of using such particles are claimed.