Janet E Talbot

US Patent:

55589871, Sep 24, 1996

Filed:

Nov 18, 1994

Appl. No.:

8/341846

Inventors:

Thomas N. Thomas - Palm Harbor FL
David V. Sheehan - Lutz FL
Janet D. Talbot - Lutz FL

Assignee:

University of South Florida - Tampa FL

International Classification:

C12Q 100
C12Q 137
G01N 3100
A61K 3800

US Classification:

435 4

Abstract:

A method of treating a patient having a panic disorder, the patient having an elevated CCK peptide plasma level, by lowering the plasma CCK peptide level of the patient. A further method provides a diagnosis of panic disorder in a patient by detecting if that patient's plasma contains elevated CCK peptide levels. A further method determines the efficacy of the drug for the treatment of panic disorder by detecting the ability of the drug to lower elevated CCK peptide levels in a model for panic disorder. Additionally, a method of dosing a patient having elevated CCK peptide levels with an antipanic disorder drug is characterized by administering the drug to a patient and monitoring the lowering of the elevated plasma CCK peptide levels of the patient.