Janice L Brissette

US Patent:

7687265, Mar 30, 2010

Filed:

Nov 24, 2004

Appl. No.:

10/997202

Inventors:

Janice Brissette - Charlestown MA, US
Lorin Weiner - Charlestown MA, US
Rong Han - Malden MA, US
Rebecca Campen - Savannah GA, US

Assignee:

The General Hospital Corporation - Boston MA

International Classification:

C12N 5/00
G01N 33/53

US Classification:

435375, 435 72

Abstract:

The present invention provides methods and compositions for modulating skin pigmentation.

US Patent:

20020192738, Dec 19, 2002

Filed:

Apr 29, 2002

Appl. No.:

10/134919

Inventors:

Janice Brissette - Charlestown MA, US
Rong Han - Boston MA, US
Lorin Weiner - Charlestown MA, US

International Classification:

G01N033/53
C12Q001/26

US Classification:

435/025000, 435/007500

Abstract:

A novel assay for tyrosinase.

US Patent:

20040110203, Jun 10, 2004

Filed:

Sep 19, 2003

Appl. No.:

10/664795

Inventors:

Seishiro Fujii - Boston MA, US
Paolo Dotto - Boston MA, US
Rong Han - Boston MA, US
Janice Brissette - Charlestown MA, US

International Classification:

C12Q001/00
C12Q001/68

US Classification:

435/006000, 435/004000

Abstract:

The invention features methods of screening for compounds that prevent and/or reduce UVB-induced skin damage, e.g., wrinkles. The method includes identifying an agent that increases or induces the expression, activity or levels of a component of the p21 signal transduction pathway. Also included are methods and compositions for treating UVB-induced skin damage.

US Patent:

20100247627, Sep 30, 2010

Filed:

Mar 30, 2010

Appl. No.:

12/750135

Inventors:

Janice Brissette - Charlestown MA, US
Lorin Weiner - Charlestown MA, US
Rong Han - Malden MA, US
Rebecca Campen - Savannah GA, US

International Classification:

A61K 9/127
A61K 36/00
A61K 36/02
A61K 31/7088
A61K 39/395
A61K 38/18
A61K 38/34
A61P 17/00

US Classification:

424450, 424725, 42419517, 514 44 R, 4241301, 514 91, 514 107, 514 89, 514 186

Abstract:

The present invention provides methods and compositions for modulating skin pigmentation.

US Patent:

20110076303, Mar 31, 2011

Filed:

Jun 25, 2010

Appl. No.:

12/823606

Inventors:

Tokuro Iwabuchi - Kanagawa, JP
Lorin Weiner - Brooklyn NY, US
Janice Brissette - Brooklyn NY, US
Jian Li - Beijing, CN

International Classification:

A61K 8/99
A61K 8/97
A61Q 5/00
A61P 17/00
A61K 36/06
A61K 36/258
A61K 36/899
A61K 36/00
C12Q 1/02
C12Q 1/68

US Classification:

42419515, 424728, 424750, 424725, 435 29, 435 6

Abstract:

An objective of the present invention is to provide an anti-graying agent. The present invention provides a method for screening an anti-graying agent whereby a substance that increases expression of AFF-4 in cells is selected by applying a candidate substance to cells in vitro; and, an anti-graying agent containing at least one type of herbal extract selected from the group consisting of (Fr.) Karst. extract, Nees extract, (Rice) Bran extract and extract selected with this method in an amount effective for increasing expression of AFF-4.