Janice L Nagy

US Patent:

56458290, Jul 8, 1997

Filed:

Jun 18, 1993

Appl. No.:

8/080474

Inventors:

Ty Robert Shockley - Highland Park IL
Robert William Jackman - Brookline MA
Janice Ann Nagy - Brookline MA

Assignee:

Beth Israel Hospital Association - Brookline MA

International Classification:

C12N 1500
C12N 500
A61K 4800
A01N 6300

US Classification:

424 9321

Abstract:

Methods and pharmaceutical compositions for modifying the mesothelial cells of a mammalian recipient in situ are provided. The methods include forming a mesothelial cell expression system in vivo or ex vivo and administering the expression system to the mammalian recipient (by way of the body cavities normally lined by mesothelial cells). The mesothelial cell expression system is useful for the localized and systemic delivery of therapeutic agents in situ.

US Patent:

60688378, May 30, 2000

Filed:

Dec 3, 1997

Appl. No.:

8/984103

Inventors:

Ty Robert Shockley - Highland Park IL
Robert William Jackman - Brookline MA
Janice Ann Nagy - Brookline MA

Assignee:

Beth Israel Hospital Association - Boston MA

International Classification:

C12N 1500
C12N 500
A61K 4800
A01N 6300

US Classification:

424 9321

Abstract:

Methods and pharmaceutical compositions for modifying the mesothelial cells of a mammalian recipient in situ are provided. The methods include forming a mesothelial cell expression system in vivo or ex vivo and administering the expression system to the mammalian recipient (by way of the body cavities normally lined by mesothelial cells). The mesothelial cell expression system is useful for the localized and systemic delivery of therapeutic agents in situ.