James M. Tour - Bellaire TX, US Jared L. Hudson - Houston TX, US Ramanan Krishnamoorti - Bellaire TX, US Koray Yurekli - Cengelkoy, TR Cynthia A. Mitchell - Houston TX, US
Assignee:
William Marsh Rice University - Houston TX
International Classification:
B60C 1/00 C08F 4/46
US Classification:
524495, 526173
Abstract:
The present invention is directed to aryl halide (such as aryl bromide) functionalized carbon nanotubes that can be utilized in anionic polymerization processes to form polymer-carbon nanotube materials with improved dispersion ability in polymer matrices. In this process the aryl halide is reacted with an alkyllithium species or is reacted with a metal to replace the aryl-bromine bond with an aryl-lithium or aryl-metal bond, respectively. It has further been discovered that other functionalized carbon nanotubes, after deprotonation with a deprotonation agent, can similarly be utilized in anionic polymerization processes to form polymer-carbon nanotube materials. Additionally or alternatively, a ring opening polymerization process can be performed. The resultant materials can be used by themselves due to their enhanced strength and reinforcement ability when compared to their unbound polymer analogs. Additionally, these materials can also be blended with pre-formed polymers to establish compatibility and enhanced dispersion of nanotubes in otherwise hard to disperse matrices resulting in significantly improved material properties.
James Tour - Bellaire TX, US Jared Hudson - McLean VA, US Koray Yurekli - Istanbul, TR Cynthia Mitchell - Houston TX, US
Assignee:
William Marsh Rice University - Houston TX The University of Houston - Houston TX
International Classification:
C08K 7/06 C01B 31/02
US Classification:
523333000, 524847000, 977742000
Abstract:
The present invention is directed to carbon nanotube-elastomer composites, methods for making such carbon nanotube-elastomer composites, and articles of manufacture made with such carbon nanotube-elastomer composites. In general, such carbon nanotube-elastomer (CNT-elastomer) composites display an enhancement in their tensile modulus (over the native elastomer), but without a large concomitant reduction in their strain-at-break.
Functionalization Of Carbon Nanotubes In Acidic Media
James Tour - Houston TX, US Jared Hudson - Houston TX, US Christopher Dyke - Humble TX, US Jason Stephenson - McLean VA, US
Assignee:
William Marsh Rice University - Houston TX
International Classification:
C01B 31/02
US Classification:
423460000
Abstract:
The present invention is generally directed to methods of functionalizing carbon nanotubes (CNTs) in acidic media. By first dispersing CNTs in an acidic medium, bundled CNTs can be separated as individual CNTs, affording exposure of the CNT sidewalls, and thereby facilitating the functionalization of such CNTs, wherein functional groups are attached to the subsequently exposed sidewalls of these individualized CNTs. Once dispersed in this substantially unhundled state, the CNTs are functionalized according to one or more of a variety of functionalization processes. Typically, ultrasonication or non-covalent wrapping is not needed to afford such dispersion and subsequent functionalization. Additionally, such methods are easily scalable and can provide for sidewall-functionalized CNTs in large, industrial-scale quantities.
Water-Soluble Carbon Nanotube Compositions For Drug Delivery And Medicinal Applications
James M. Tour - Bellaire TX, US Valerie C. Moore - Houston TX, US Jeffrey N. Myers - Bellaire TX, US Zvonimir L. Milas - Houston TX, US Kathy A. Mason - Houston TX, US Luka Milas - Houston TX, US Brandl Katherine Price - Houston TX, US Jared L. Hudson - Hamilton VA, US Ashley Leonard - Houston TX, US Dmitry V. Kosynkin - Houston TX, US
Assignee:
William Marsh Rice University - Houston TX
International Classification:
A61K 38/18 A61K 31/337 A61K 47/04
US Classification:
514 12, 514449, 514769, 977746, 977750, 977906
Abstract:
Compositions comprising a plurality of functionalized carbon nanotubes and at least one type of payload molecule are provided herein. The compositions are soluble in water and PBS in some embodiments. In certain embodiments, the payload molecules are insoluble in water. Methods are described for making the compositions and administering the compositions. An extended release formulation for paclitaxel utilizing functionalized carbon nanotubes is also described.