Jason Eric Donald from 7 Blinn Rd, Lexington, MA 02421, age 45

Jason Mac Donald

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Jason Donald

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Location:

United States

Jas Dald (baseball)

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Jason Thomas Donald (born September 4, 1984) is an Olympian for the United States and a Major League Baseball utility player who currently plays for the ...

Jason Donald (Baseball)

Jason Donald (Cyclist)

Us Patents

Metabolic Engineering For Microbial Production Of Terpenoid Products
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US Patent:

20220364127, Nov 17, 2022
Filed:

Apr 26, 2022
Appl. No.:

17/729056
Inventors:

- CAMBRIDGE MA, US
Souvik GHOSH - Walnut Creek CA, US
Christopher PIRIE - Seattle WA, US
Jason DONALD - Lexington MA, US
Aaron LOVE - Boston MA, US
Hong NAN - Daly City CA, US
Hsien-Chung TSENG - Cambridge MA, US
Christine Nicole S. SANTOS - Newton MA, US
Ryan PHILIPPE - Somerville MA, US
International Classification:

C12P 5/00
C12N 9/02
C12N 9/04
C12N 9/10
Abstract:

In various aspects and embodiments, the invention relates to bacterial strains and methods for making terpene and terpenoid products. The invention provides bacterial strains with improved carbon flux through the MEP pathway, to thereby increase terpene and/or terpenoid product yield by fermentation with carbon sources such as glucose.

Metabolic Engineering For Microbial Production Of Terpenoid Products
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US Patent:

20220251607, Aug 11, 2022
Filed:

Apr 26, 2022
Appl. No.:

17/729096
Inventors:

- Cambridge MA, US
Ryan LIM - Cambridge MA, US
Jason DONALD - Lexington MA, US
Hsien-Chung TSENG - Cambridge WA, US
Christine Nicole S. SANTOS - Newton MA, US
Ryan PHILIPPE - Somerville MA, US
International Classification:

C12P 5/00
C12N 9/02
C12N 15/52
C12P 7/04
Abstract:

The invention relates to methods and bacterial strains for making terpene and terpenoid products, the bacterial strains having improved carbon pull through the MEP pathway and to a downstream recombinant synthesis pathway.

Microbial Production Of Mogrol And Mogrosides
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US Patent:

20230042171, Feb 9, 2023
Filed:

Dec 16, 2020
Appl. No.:

17/785488
Inventors:

- Cambridge MA, US
Ryan N. PHILIPPE - Orleans, CA
Ajikumar Parayil KUMARAN - Cambridge MA, US
Christine Nicole S. SANTOS - Cambridge MA, US
Jason Eric DONALD - Cambridge MA, US
Christopher FREI - Cambridge MA, US
Aaron LOVE - Cambridge MA, US
Kaitlin CHAMBERS - Cambridge MA, US
Joyce SAMSON - Cambridge MA, US
Christopher TOOMEY - Cambridge MA, US
International Classification:

C12P 17/02
C12N 9/02
C12N 9/14
C12P 19/18
C12P 19/56
C12P 5/00
Abstract:

The present invention provides host cells and methods for making mogrol glycosides, including Mogroside V (Mog.V), Mogroside VI (Mog.VI), Iso-Mogroside V (Isomog.V), siamenoside, and glycosylation products that are minor products in . The invention provides engineered enzymes and engineered host cells for producing mogrol glycosylation products, such as Mog.V, Mog.VI, and Isomog.V, at high purity and/or yield. The present technology further provides methods of making products containing mogrol glycosides, such as Mog.V, Mog.VI, and Isomog.V, including food products, beverages, oral care products, sweeteners, and flavoring products.

Microbial Production Of Rotundone
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US Patent:

20210254107, Aug 19, 2021
Filed:

Sep 6, 2019
Appl. No.:

17/273567
Inventors:

- Cambridge MA, US
AJIKUMAR PARAYIL KUMARAN - Cambridge MA, US
CHRISTINE NICOLE S. SANTOS - Cambridge MA, US
JASON DONALD - Cambridge MA, US
STEPHEN SARRIA - Cambridge MA, US
International Classification:

C12P 7/26
C12N 15/52
C12N 9/04
C12N 9/02
C12N 9/10
C12N 9/88
Abstract:

The present disclosure provides methods and compositions for producing rotundone. In various aspects, the present disclosure provides enzymes, polynucleotides encoding said enzymes, and recombinant microbial host cells (or microbial host strains) for the production of rotundone. In some embodiments, the present disclosure provides microbial host cells for producing rotundone at high purity and/or yield, from either enzymatic transformation of α-guaiene, or from sugar or other carbon source. The present disclosure further provides methods of making products containing rotundone, including flavor or fragrance products, among others.

Biosynthesis And Recovery Of Secondary Metabolites
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US Patent:

20210207078, Jul 8, 2021
Filed:

Jan 19, 2021
Appl. No.:

17/151871
Inventors:

- Cambridge MA, US
Adel GHADERI - Cambridge MA, US
Jason Eric DONALD - Cambridge MA, US
Christine Nicole S. SANTOS - Cambridge MA, US
Ajikumar Parayil KUMARAN - Cambridge MA, US
International Classification:

C12N 1/20
C12N 1/16
C12N 1/26
C12P 5/00
Abstract:

Aspects of the invention provide methods for producing one or more secondary metabolites from microbial culture. In various embodiments, the method comprises culturing a microbial cell producing a secondary metabolite for recovery from a bioreactor medium, the medium comprising an aqueous phase and an extraction phase. The composition of the extraction phase, and the relevant amount with respect to the aqueous phase, enhances production of the secondary metabolite from microbial cells and/or enhances extracellular transfer of the metabolite.

Microbial Production Of Steviol Glycosides
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US Patent:

20210022373, Jan 28, 2021
Filed:

Apr 29, 2020
Appl. No.:

16/862214
Inventors:

- Cambridge MA, US
Ajikumar Parayil KUMARAN - Cambridge MA, US
Jason DONALD - Cambridge MA, US
Krishna PATEL - Cambridge MA, US
Swati GUPTA - Cambridge MA, US
Ryan LIM - Cambridge MA, US
Liwei LI - Cambridge MA, US
International Classification:

A23L 2/60
A23L 27/30
C12P 19/56
C12N 9/10
C12N 9/02
Abstract:

The invention provides methods for making steviol glycosides, including RebM and glycosylation products that are minor products in leaves, and provides enzymes, encoding polynucleotides, and host cells for use in these methods. The invention provides engineered enzymes and engineered host cells for producing steviol glycosylation products, such as RebM, at high purity and/or yield. The invention further provides methods of making products containing steviol glycosides, such as RebM, including food products, beverages, oral care products, sweeteners, and flavoring products.

Metabolic Engineering For Microbial Production Of Terpenoid Products
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US Patent:

20210002672, Jan 7, 2021
Filed:

Aug 13, 2020
Appl. No.:

16/992773
Inventors:

- Cambridge MA, US
Ryan LIM - Cambridge MA, US
Jason DONALD - Cambridge MA, US
Hsien-Chung TSENG - Cambridge MA, US
Christine Nicole S. SANTOS - Cambridge MA, US
Ryan PHILIPPE - Cambridge MA, US
International Classification:

C12P 5/00
C12N 9/02
C12N 15/52
C12P 7/04
Abstract:

The invention relates to methods and bacterial strains for making terpene and terpenoid products, the bacterial strains having improved carbon pull through the MEP pathway and to a downstream recombinant synthesis pathway.

Metabolic Engineering For Microbial Production Of Terpenoid Products
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US Patent:

20200299735, Sep 24, 2020
Filed:

Apr 29, 2020
Appl. No.:

16/862209
Inventors:

- Cambridge MA, US
Souvik GHOSH - Walnut Creek CA, US
Christopher PIRIE - Seattle WA, US
Jason DONALD - Lexington MA, US
Aaron LOVE - Boston MA, US
Hong NAN - Daly City CA, US
Hsien-Chung TSENG - Cambridge MA, US
Christine Nicole S. SANTOS - Newton MA, US
Ryan PHILIPPE - Somerville MA, US
International Classification:

C12P 5/00
C12N 9/02
C12N 9/04
C12N 9/10
Abstract:

In various aspects and embodiments, the invention relates to bacterial strains and methods for making terpene and terpenoid products. The invention provides bacterial strains with improved carbon flux through the MEP pathway, to thereby increase terpene and/or terpenoid product yield by fermentation with carbon sources such as glucose.