Jason M Mcclure

US Patent:

7999933, Aug 16, 2011

Filed:

Aug 14, 2009

Appl. No.:

12/541586

Inventors:

Jason McClure - Acton MA, US

Assignee:

Princeton Instruments - Acton MA

International Classification:

G01J 3/00

US Classification:

356300

Abstract:

Disclosed is a method for calibrating optical spectrographs, and in particular optical spectrographs having focal plane array detectors. The method comprises the steps of detecting a spectrum of a known source, referencing a table of known spectral wavelengths and relative intensities, and deriving a spectrograph model based on the spectrograph's physical properties to approximate the observed spectrum, wherein non-linear optimization techniques refine the theoretical model parameters, thereby minimizing the residual difference between observed and calculated spectral intensities in an iterative process producing a set of physical model parameters that best describe the modeling spectrograph for calibration of subsequent spectral acquisitions.

US Patent:

8050731, Nov 1, 2011

Filed:

Nov 16, 2005

Appl. No.:

11/280672

Inventors:

Mark A. Tapsak - San Diego CA, US
Rathbun K. Rhodes - Madison WI, US
Mark C. Shults - Madison WI, US
Jason D. McClure - San Diego CA, US

Assignee:

DexCom, Inc. - San Diego CA

International Classification:

G01N 27/26
A61B 5/00
A61B 5/05

US Classification:

600347, 20440305, 20440311, 20440313, 424424, 21050021, 427 212, 6048911, 600365

Abstract:

The invention provides an implantable membrane for regulating the transport of analytes therethrough that includes a matrix including a first polymer; and a second polymer dispersed throughout the matrix, wherein the second polymer forms a network of microdomains which when hydrated are not observable using photomicroscopy at 400× magnification or less. In one aspect, the homogeneous membrane of the present invention has hydrophilic domains dispersed substantially throughout a hydrophobic matrix to provide an optimum balance between oxygen and glucose transport to an electrochemical glucose sensor.

US Patent:

8436423, May 7, 2013

Filed:

Jan 20, 2011

Appl. No.:

13/010328

Inventors:

William Edward Asher - Leominster MA, US
Michael Alan Case - Stow MA, US
Jason McClure - Acton MA, US

Assignee:

Roper Scientific, Inc. - Tucson AZ

International Classification:

H01L 29/00

US Classification:

257341, 257342

Abstract:

A backside-illuminated image sensor is disclosed having improved quantum efficiency (QE) in the near infrared wavelengths (NIR: 750-1100 nm) with minimal optical interference fringes produced by multiple reflected rays within the photosensitive Si region of the sensor, which may be a charge-coupled device, a complementary metal oxide sensor or an electron-multiplication sensor. The invention comprises a fringe suppression layer applied to the backside surface of the photosensitive Si region of a detector (Si substrate) whereby the fringe suppression layer functions in concert with the Si substrate to reduce the occurrence of interference fringes in the NIR while maintaining a high QE over a broad range of wavelengths (300-1100 nm). The combination of a fringe suppression layer applied to a Si substrate provides a new class of back illuminated solid state detectors for imaging.

US Patent:

20030217966, Nov 27, 2003

Filed:

May 22, 2002

Appl. No.:

10/153356

Inventors:

Mark Tapsak - San Diego CA, US
Rathbun Rhodes - Madison WI, US
Mark Shults - Madison WI, US
Jason McClure - San Diego CA, US

Assignee:

Dexcom, Inc. - San Diego CA

International Classification:

A61K031/00

US Classification:

210/500210, 210/500270, 210/500340

Abstract:

The invention provides an implantable membrane for regulating the transport of analytes therethrough that includes a matrix including a first polymer; and a second polymer dispersed throughout the matrix, wherein the second polymer forms a network of microdomains which when hydrated are not observable using photomicroscopy at 400× magnification or less. In one aspect, the homogeneous membrane of the present invention has hydrophilic domains dispersed substantially throughout a hydrophobic matrix to provide an optimum balance between oxygen and glucose transport to an electrochemical glucose sensor.

US Patent:

20060068208, Mar 30, 2006

Filed:

Nov 16, 2005

Appl. No.:

11/280102

Inventors:

Mark Tapsak - San Diego CA, US
Rathbun Rhodes - Madison WI, US
Mark Shults - Madison WI, US
Jason McClure - San Diego CA, US

International Classification:

B32B 27/40

US Classification:

428423100, 525296000, 525420000

Abstract:

The invention provides an implantable membrane for regulating the transport of analytes therethrough that includes a matrix including a first polymer; and a second polymer dispersed throughout the matrix, wherein the second polymer forms a network of microdomains which when hydrated are not observable using photomicroscopy at 400× magnification or less. In one aspect, the homogeneous membrane of the present invention has hydrophilic domains dispersed substantially throughout a hydrophobic matrix to provide an optimum balance between oxygen and glucose transport to an electrochemical glucose sensor.

US Patent:

20100041971, Feb 18, 2010

Filed:

Oct 29, 2009

Appl. No.:

12/608872

Inventors:

Arnold L. Holmquist - San Diego CA, US
Mark A. Tapsak - Orangeville PA, US
Mark Shults - Madison WI, US
Victoria Carr-Brendel - San Diego CA, US
James H. Brauker - Cement City MI, US
Paul V. Neale - San Diego CA, US
Jason D. McClure - San Diego CA, US
Mark Brister - Encinitas CA, US
Peter C. Simpson - Encinitas CA, US
Rathbun K. Rhodes - Madison WI, US

Assignee:

DexCom, Inc. - San Diego CA

International Classification:

A61B 5/1468
H01R 43/00

US Classification:

600345, 29825

Abstract:

An implantable analyte sensor including a sensing region for measuring the analyte and a non-sensing region for immobilizing the sensor body in the host. The sensor is implanted in a precisely dimensioned pocket to stabilize the analyte sensor in vivo and enable measurement of the concentration of the analyte in the host before and after formation of a foreign body capsule around the sensor. The sensor further provides a transmitter for RF transmission through the sensor body, electronic circuitry, and a power source optimized for long-term use in the miniaturized sensor body.

US Patent:

20130196337, Aug 1, 2013

Filed:

Jul 31, 2012

Appl. No.:

13/563542

Inventors:

Peter Yan-Guo Ren - San Diego CA, US
Jason McClure - San Diego CA, US
Kevin S. Richardson - San Diego CA, US

Assignee:

Quidel Corporation - San Diego CA

International Classification:

G01N 33/569

US Classification:

435 71, 4352872

Abstract:

Methods, compositions and kits for detecting Group A in a biological sample are described. More particularly, the present disclosure provides an immunoassay in which the specificity of detection of Group A is enhanced by addition of N-acetyl-D-glucosamine. These methods, compositions and kits are useful in convenient, reliable and early diagnosis of streptococcal infection in a human subject.

US Patent:

20220184605, Jun 16, 2022

Filed:

Mar 4, 2022

Appl. No.:

17/687413

Inventors:

- San Diego CA, US
Jason McClure - San Diego CA, US
Robert Reed - Carlsbad CA, US
Irene Sinn Blandy - San Diego CA, US
Robert Weiller - Encinitas CA, US
Christian Bobritchi - San Diego CA, US

International Classification:

B01L 3/00
G01N 33/558
G01N 33/543

Abstract:

A substrate structured to define thereon a fluid flow channel and/or a fluid control feature is described. The substrate may additionally comprise a capture zone and/or a test zone, for use as a test strip for determining presence or absence of an analyte of interest, such as an infectious agent or a biomarker. Reagents are deposited in the capture zone and/or test zone as an array of drops.