Jason M Montez

US Patent:

7674891, Mar 9, 2010

Filed:

Aug 1, 2008

Appl. No.:

12/184368

Inventors:

Stephen Anthony Gravina - Rutherford NJ, US
Jason M. Montez - Rumson NJ, US
Hailin Wang - East Brunswick NJ, US

Assignee:

International Flavors & Fragrances Inc. - New York NY

International Classification:

C07H 21/02
C07H 21/04
C12P 21/06
C12N 1/20
C12N 15/00
C12N 5/00
C12N 5/02
C12N 15/74

US Classification:

536 231, 435 691, 4352523, 4353201, 435325, 435471

Abstract:

The present invention is an isolated nucleic acid molecule encoding CD36, G, and G protein-coupled receptor 84 (GPR84) proteins as well as vectors and recombinant host cells which co-express CD36, G, and GPR84 proteins for use in identifying modulators of GPR84 activity.

US Patent:

20090106853, Apr 23, 2009

Filed:

Feb 17, 2005

Appl. No.:

10/589052

Inventors:

Kambiz Shekdar - New York NY, US
Dennis J. Sawchuk - Hoboken NJ, US
Jason M. Montez - Rumson NJ, US

International Classification:

C12N 15/00
C12N 5/00
C40B 50/06
C40B 40/02
C40B 30/06
C12N 5/02
C12Q 1/68

US Classification:

800 21, 435325, 506 26, 435375, 435 6, 506 14, 506 10

Abstract:

The present invention relates to methods of isolating cells or generating cell lines using signaling probes that produce a signal upon hybridization to a target sequence. Other methods that utilize the signaling probe include methods of quantifying the level of RNA expression, methods for identifying genetic recombinational events in living cells and methods of generating a transgenic animal using the isolated cells. The invention also provides protease probes. Signaling probes and protease probes that form stem-loop structures, three-arm junction structures, and dumbbell structures are provided.

US Patent:

20090148938, Jun 11, 2009

Filed:

Dec 6, 2007

Appl. No.:

11/951793

Inventors:

Stephen Anthony Gravina - Rutherford NJ, US
Jason Michael Montez - Rumson NJ, US
Vijyeta Kapur - Monroe NJ, US
Carrie Ann Maxwell - Brick NJ, US
Mark L. Dewis - Matawan NJ, US

International Classification:

C12N 5/06
G01N 33/566

US Classification:

435325, 436501

Abstract:

The Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1) protein has been identified as an ester cooler receptor and therefore is useful in screening assays for identifying ester coolers, in particular ester coolers with a relative cooling strength which exceeds (−)−menthol.

US Patent:

20150299782, Oct 22, 2015

Filed:

Nov 6, 2014

Appl. No.:

14/534896

Inventors:

- NORTH BRUNSWICK NJ, US
Dennis J. Sawchuk - Fanwood NJ, US
Jason M. Montez - Hoboken NJ, US

International Classification:

C12Q 1/68

Abstract:

Methods of isolating cells or generating cell lines comprising the step of exposing the cells to signaling probes that produce a signal upon hybridization to a target sequence, as well as methods of quantifying the level of expression of an RNA of interest, methods for identifying genetic recombinational events in living cells and methods of generating a transgenic animal using the isolated cells. Methods for isolating a plurality of cells encoding a plurality of different RNAs associated with a same nucleic acid tag sequence, comprising the step of exposing the cells to a same signaling probe that produces a detectable signal upon hybridization to the same nucleic acid tag sequence, are also provided. Signaling probes and protease probes that form stem-loop structures, three-arm junction structures, and dumbbell structures may be used in the above methods.