Jason B. O'Connor - South Boston MA, US Luis Malave - Reading MA, US
Assignee:
INSULET CORPORATION - Bedford MA
International Classification:
A61M 5/142
US Classification:
604151
Abstract:
A prefilled syringe may be interfaced with and used to fill an infusion pump with therapeutic liquid. The dispensing end of the prefilled syringe may be coupled (either directly or indirectly using a syringe cap) to a syringe coupling region of the infusion pump, for example, using a threaded engagement or snap fit engagement. As the dispensing end of the prefilled syringe is coupled to the syringe coupling region of the pump housing, a needle passes through the pump housing and/or a needle passage region of the dispensing end such that the prefilled syringe is fluidly coupled to a reservoir in the pump. In various embodiments, the needle may be located in the syringe coupling region or in a syringe cap coupled to the dispensing end of the prefilled syringe.
Medicament Delivery Device With An Adjustable And Piecewise Analyte Level Cost Component To Address Persistent Positive Analyte Level Excursions
- Acton MA, US Eric BENJAMIN - Cambridge MA, US Jason O'CONNOR - Acton MA, US Yibin ZHENG - Hartland WI, US
International Classification:
G16H 20/13 A61M 5/172
Abstract:
The exemplary embodiments may modify a glucose cost component of the cost function of the control loop of an insulin delivery device to compensate for persistent positive low level glucose excursions relative to a target glucose level. The exemplary embodiments may enable use of different glucose cost component functions for different glucose levels of the user. These glucose cost component functions may be employed in piecewise fashion with a different piece being applied for each respective range of glucose level values for the user. The final glucose cost function for calculating the glucose cost component may be a weighted combination of a piecewise glucose cost function and a weighted standard cost function (such as a quadratic function). The weights may reflect the magnitude and/or persistence of glucose excursions relative to a target glucose level.
Techniques And Devices For Adaptation Of Maximum Drug Delivery Limits
- Acton MA, US Joon Bok LEE - Acton MA, US Jason O'CONNOR - Acton MA, US
International Classification:
A61M 5/172 G16H 20/17 A61B 5/145 A61M 5/142
Abstract:
Disclosed are techniques, a system and devices that enable the setting of an upper boundary constraint that may be a multiple of a total daily dosage setting for a liquid drug being administered to a user to control a condition, such as type 1 or type 2 diabetes mellitus. An automatic drug delivery algorithm may be configured to obtain a glucose control metric. A controller executing the automatic drug delivery algorithm may ascertain, based on the glucose control metric, an upper boundary constraint for the liquid drug that limits an amount of a dose of the liquid drug that may be delivered by the automatic drug delivery system or components thereof.
Automated Insulin Delivery System Using Pramlintide
Disclosed herein are systems and methods for the delivery of insulin and pramlintide using an automated insulin delivery system. In a first embodiment, a drug delivery system is configured to deliver independent doses of insulin and pramlintide. The system monitors the user's blood glucose level and determines when a meal is been ingested and, in response, delivers the dose of pramlintide which, in turn alters the required delivery of insulin. In the second embodiment, the drug delivery system is configured to deliver a co-formulation of insulin and pramlintide as basal doses. The total amount of pramlintide delivered in a most recent pre-determine period of time, for example, 24 hours, is used to alter the aggressiveness of the algorithm which determines the basal doses of the co-formulation.
Systems And Methods For Incorporating Co-Formulations Of Insulin In An Automatic Insulin Delivery System
- Acton MA, US Jason O'CONNOR - Acton MA, US Yibin ZHENG - Hartland WI, US Ashutosh ZADE - San Diego CA, US
International Classification:
A61M 5/172 G16H 20/17
Abstract:
Disclosed herein are systems and methods for the delivery of a co-formulation of insulin and a second drug, such as GLP-1, using an automated insulin delivery system. In a first embodiment, a dose of insulin is calculated by a medication delivery algorithm and a reduction factor is applied to account for the effect of second drug on the user's daily insulin requirement. In a second embodiment of the invention, a total amount of the second drug administered to the user during the past 24 hours is used to modify the correction factor and the insulin-to-carbohydrate ratio used by the medication delivery algorithm to cause a reduction in the insulin delivered to the user to account for the effect of the administration of the second drug portion of the co-formulation.
Compensation For Missing Readings From A Glucose Monitor In An Automated Insulin Delivery System
- Acton MA, US Joon Bok LEE - Acton MA, US Ashutosh ZADE - San Diego CA, US Jason O'CONNOR - Acton MA, US
International Classification:
A61M 5/172 G06F 17/17
Abstract:
Exemplary embodiments may address the problem of missing blood glucose concentration readings from a glucose monitor that transmits blood glucose concentration readings over a wireless connection due to problems with the wireless connection. In the exemplary embodiments, an automated insulin delivery (AID) device uses an estimate in place of a missing blood glucose concentration reading in determining a predicted future blood glucose concentration reading for a user. Thus, the AID device is able to operate normally in generating insulin delivery settings despite not receiving a current blood glucose concentration reading for a current cycle. There is no need to suspend delivery of insulin to the user due to the missing blood glucose concentration reading.
Scheduling Of Medicament Bolus Deliveries By A Medicament Delivery Device At Future Dates And Times With A Computing Device
Exemplary embodiments may enable a user to schedule medicament bolus deliveries, such as insulin boluses, for future dates and times. The exemplary embodiments may provide the ability to delay a scheduled medicament bolus delivery by short periods of time. The user may reschedule a scheduled medicament bolus delivery by entering a new date and/or time for the medicament bolus delivery. Still further, a user may cancel a scheduled medicament bolus delivery. In addition, exemplary embodiments may enable multiple medicament bolus deliveries to be viewed and managed.
Techniques For Recommending Rescue Carbohydrate Ingestion In Automatic Medication Delivery Systems
- Acton MA, US Matthew ALLES - Winchester MA, US Yibin ZHENG - Hartland WI, US Jason O'CONNOR - Acton MA, US
International Classification:
A61M 5/172
Abstract:
Provided are techniques, devices and systems that include monitoring a trend of blood glucose measurement values over a series of measurement cycles. A processor may identify a potential excursion outside a range of a target blood glucose measurement value setting of a user based on the monitored trend. In response to the identified potential excursion, an alert may be generated to the user to consume rescue carbohydrates. In addition, the disclosed techniques may include a processor that assesses the factors related to a potential impending hypoglycemic event for a user. Based on a result of the assessment of the factors, the processor may determine whether the user is approaching the potential impending hypoglycemic event for the user. In response to a determination that the user is approaching the potential impending hypoglycemic event for the user, a number of rescue carbohydrates to suggest for consumption by the user may be determined.
Jun 2013 to 2000 Director of Business DevelopmentKaplan Publishing New York, NY Jan 2008 to Sep 2012 Associate Director of Sales and MarketingMcGraw-Hill Medical New York, NY Jul 2006 to Jan 2008 Outside Sales RepresentativeElsevier Publishing New York, NY Jul 2003 to Jul 2006 Outside Sales RepresentativePearson Education Boston, MA 1998 to 2001 Outside Sales Representative
Education:
University of Massachusetts Boston, MA 1997 Bachelor of Arts in Economics
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Jason O'connor
J. O'CONNOR LANDSCAPING LLC
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