Amgen since Aug 2005
Principal Scientist
Fred Hutchinson Cancer Research Center Jun 2001 - Aug 2005
Research Scientist
University of California at San Diego Sep 1991 - Aug 1994
Research Associate
Education:
University of Washington 1994 - 2001
PhD, Protein Biochemistry, X-ray Crystallography
University of California, San Diego 1988 - 1991
BS, Biology
Skills:
Protein Chemistry Cell Culture Monoclonal Antibodies Protein Purification Biopharmaceuticals Project Management Hplc Molecular Biology Research Protein Chromatography Protein Engineering Biochemistry Biotechnology Industry Oncology Drug Development Purification Biophysics Antibodies Pcr Cell Biology Protein Expression Chromatography Management Operations Management Protein Characterization X Ray Crystallography
Jennifer E. Towne - Seattle WA, US Janet D. Cheng - Seattle WA, US Jason C. O'Neill - Brier WA, US Yu Zhang - Shoreline WA, US Yu Sun - Seattle WA, US Heather Cerne - Seattle WA, US Derek E. Piper - Santa Clara CA, US Randal R. Ketchem - Snohomish WA, US
Antigen binding proteins that bind to human IL-23 protein are provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same as well as use of IL-23 antigen binding proteins for diagnostic and therapeutic purposes are also provided.
Activin Receptor Type Ii Chimeras And Methods Of Use Thereof
- Lexington MA, US Jennifer LACHEY - Lincoln MA, US Claire TSENG - Newton MA, US Jason O'NEILL - Lake Forest Park WA, US Henning THØGERSEN - Farum, DK Elissa FURUTANI - Belmont MA, US
The invention features polypeptides that include an extracellular ActRII chimera. In some embodiments, a polypeptide of the invention includes an extracellular ActRII chimera fused to an Fc domain monomer or moiety. The invention also features pharmaceutical compositions and methods of using the polypeptides to treat diseases and conditions involving weakness and atrophy of muscles, bone damage, low red blood cell levels (e.g., anemia or blood loss), low platelet levels (e.g., thrombocytopenia), low neutrophil levels (e.g., neutropenia), fibrosis, metabolic disorders, and/or pulmonary hypertension.
- Thousand Oaks CA, US Janet D. Cheng - Montclair CA, US Jason C. O'Neill - Brier WA, US Yu Zhang - Shoreline WA, US Yu Sun - Seattle WA, US Heather Cerne - Seattle WA, US Derek E. Piper - Santa Clara CA, US Randal R. Ketchem - Snohomish WA, US
International Classification:
C07K 16/24 A61K 47/68 A61K 39/395
Abstract:
Antigen binding proteins that bind to human IL-23 protein are provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same as well as use of IL-23 antigen binding proteins for diagnostic and therapeutic purposes are also provided.
- Thousand Oaks CA, US Janet D. Cheng - Seattle WA, US Jason C. O'Neill - Brier WA, US Yu Zhang - Shoreline WA, US Yu Sun - Seattle WA, US Heather Cerne - Seattle WA, US Derek E. Piper - Santa Clara CA, US Randal R. Ketchem - Snohomish WA, US
International Classification:
C07K 16/24 A61K 39/395 A61K 47/68
Abstract:
Antigen binding proteins that bind to human IL-23 protein are provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same as well as use of IL-23 antigen binding proteins for diagnostic and therapeutic purposes are also provided.
- Thousand Oaks CA, US Janet D. Cheng - Seattle WA, US Jason C. O'Neill - Brier WA, US Yu Zhang - Shoreline WA, US Yu Sun - Seattle WA, US Heather Cerne - Seattle WA, US Derek E. Piper - Santa Clara CA, US Randal R. Ketchem - Snohomish WA, US
International Classification:
C07K 16/24 A61K 39/395 A61K 47/68
Abstract:
Antigen binding proteins that bind to human IL-23 protein are provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same as well as use of IL-23 antigen binding proteins for diagnostic and therapeutic purposes are also provided.
Variants Of Tissue Inhibitor Of Metalloproteinase Type Three (Timp-3), Compositions And Methods
- Thousand Oaks CA, US Jason Charles O'Neill - Brier WA, US Randal R. Ketchem - Snohomish WA, US Randy Ira Hecht - Raleigh NC, US Edward J. Belouski - Thousand Oaks CA, US Mark Leo Michaels - Encino CA, US
International Classification:
C07K 14/81 C12N 9/64 A61K 38/00
Abstract:
There are disclosed TIMP-3 muteins, variants and derivatives, nucleic acids encoding them, and methods of making and using them.
- Thousand Oaks CA, US Janet D. Cheng - Seattle WA, US Jason C. O'Neill - Brier WA, US Yu Zhang - Shoreline WA, US Yu Sun - Seattle WA, US Heather Cerne - Seattle WA, US Derek E. Piper - Santa Clara CA, US Randal R. Ketchem - Snohomish WA, US
International Classification:
C07K 16/24 A61K 39/395 A61K 47/68 A61K 39/00
Abstract:
Antigen binding proteins that bind to human IL-23 protein arc provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same as well as use of IL-23 antigen binding proteins for diagnostic and therapeutic purposes arc also provided.
- Thousand Oaks CA, US Michelle BLAKE - Arlington MA, US Jason Charles O'NEILL - Brier WA, US Gunasekaran KANNAN - Newbury Park CA, US Jiangchun XU - San Diego CA, US Mark Edward TOMETSKO - Seattle WA, US
The present invention relates to BCMA (B-Cell Maturation Antigen) antigen binding proteins, such as antibodies, polynucleotide sequences encoding said antigen binding proteins, and compositions and methods for diagnosing and treating diseases. The present invention also relates to BCMA antibody drug conjugates.
Youtube
Jason O'Neill (Pencil Bugs) KNSD TV Interview
Right before Christmas 2008, I was interviewed on live news at KNSD-TV...
Category:
People & Blogs
Uploaded:
21 Oct, 2009
Duration:
3m 53s
TEDxRedmond - Jason O'Neill - Goals vs. Plans
TEDxRedmond is "by kids, for kids" with a theme of "Power to the Stude...
Category:
Travel & Events
Uploaded:
06 Oct, 2010
Duration:
5m 26s
Jason O'Neill-Pencil Bugs speaking at Champio...
Jason O'Neill speaking at Champions Against Bullying charity concert o...
Category:
Entertainment
Uploaded:
03 Apr, 2010
Duration:
2m 22s
Jason O'Neill & Katie Gilbert
"Mega Book Marketing" event 2009 13 year old, Jason O'Neill shares his...
Category:
People & Blogs
Uploaded:
10 Jun, 2009
Duration:
1m 35s
Jason O'Neill v Pearse Ogs.flv
Granemore captain speaks after Granemore shock Pearse gs in the Armagh...
Category:
Sports
Uploaded:
04 Sep, 2010
Duration:
1m 41s
TEDxRedmond - Interview with Jason O'Neill Th...
Amazing-Kids Reporter Olivia interviews Jason O'Neill, creator/founder...
Category:
Travel & Events
Uploaded:
14 Oct, 2010
Duration:
4m 47s
Googleplus
Jason O'neill
Work:
Clearnet Communications TELUS
Education:
University of Western Ontario
Jason O'neill
Education:
William Paterson University - Undecided
About:
MetsRefugees
Jason O'neill
Work:
National Physical Laboratory - Higher Research Scientist (2012)